Cancer: Principles and Practice of Oncology / Edition 6

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Acclaimed by the worldwide medical community as the standard-setting oncology reference, Cancer: Principles and Practice of Oncology is now in its Sixth Edition. This thoroughly revised and updated classic reflects the latest breakthroughs in every aspect of oncology, from molecular biology, to multimodality treatment, to new data on cancer prevention by drugs and diet.This edition places increased emphasis on the role of molecular biology in cancer diagnosis and treatment. In light of the growing clinical importance of biological therapy, a new section on Pharmacology of Cancer Biotherapeutics has been added. Chapters describe new radiotherapy techniques such as intensity-modulated radiation therapy and innovative surgical techniques such as radiofrequency ablation of tumors, isolation-perfusion for visceral cancers, and image-guided surgery. Rehabilitation is integrated into each of this edition's chapters on organ-specific cancers. Also included are new chapters on information systems in oncology, particularly on accessing information from the World Wide Web.This edition now includes a CD-ROM bound into the book. The CD-ROM has advanced search capabilities and gives you full text, high-quality video and color slides not found in the book, direct links to PubMed, and links to our new oncology portal, The CD-ROM is also available separately.

The sixth edition is a revision that lives up to its sterling reputation. In this edition, there is greater emphasis on the role of molecular biology in cancer diagnosis and treatment; a new section on the pharmacology of cancer biotherapeutics; the latest on cancer prevention; new chapters on innovative surgical and radiotherapeutic techniques; a focus on rehabilitation; and much more. The accompanying CD-ROM provides full text, illustrations, and color slides not found in the book, and direct links to PubMed, and to Lippincott's new oncology portal.

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Editorial Reviews

British Journal of Surgery
A worthy successor to the previous editions ... Will maintain its pre-eminent position.
Journal of the National Cancer Institute
I cannot live without my Cancer: Principles and Practice of Oncology.
ASCO Online
Editions of this book are to be found on the shelves of every practicing oncologist in both Europe and the United States and rightly so. It is well indexed and comprehensive, allowing clinicians to quickly dip into its pages and sound knowledgeable on the treatment of rare fascinations.
Annals of Internal Medicine
Comprehensive...a coordinated, balanced, multimethod approach to the management of patients with cancer.
This famous classic has gained a worldwide reputation as the source of definitive clinical information in the treatment of cancer. Four sections present the essentials of molecular biology, signal transduction, and immunology; updated information on the cell cycle, cytogenetics, the metastatic process, causes of cancer, and the principles of chemotherapy, radiation therapy, and surgery, as well as those related to molecular pathology, cancer genetics, and biologic therapy; chapters on cancers of individual organ systems, cancer prevention, imaging techniques, and supportive and palliative care; and newer approaches in cancer treatment, including cancer vaccines, gene therapy, and immunotoxin therapy. Annotation c. by Book News, Inc., Portland, Or.
<:st> Earlier editions are cited in as an initial choice and a core work for the smallest of medical libraries. This is the new edition of a text that describes underlying recent clinical developments in oncology as well as complete information to aid the clinician in the panorama of clinical care ranging from cancer prevention to the care of the terminally ill patient. The initial contributions present a summary of the major areas of modern bioscience necessary for an understanding of recent developments in oncology. Subsequent sections discuss the specific scientific areas of greatest relevance to the oncologist, including new chapters on cytogenetics, the cell cycle, apoptosis, angiogenesis, the etiology of cancer, modern epidemiologic methods, and the incidence of and mortality from cancer; the specific, practical information needed for the management of each cancer patient; and future developments with special sections on gene and molecular therapy, vaccines, image-guided surgery, and proton beam radiation therapy. Each major treatment section is co-authored by a surgeon, a medical oncologist, and a radiation oncologist; and treatments are described in terms of the stage of presentation of the patient and the role of each modality. Edited by DeVita (director, Yale Cancer Center), Samuel Hellman (radiation and cellular oncology, U. of Chicago) and Steven A. Rosenberg (surgery, National Cancer Institute). Includes a CD-ROM version. Annotation c. Book News, Inc., Portland, OR (
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Product Details

  • ISBN-13: 9780781723879
  • Publisher: Lippincott Williams & Wilkins
  • Publication date: 1/28/2001
  • Edition description: Sixth Edition
  • Edition number: 6
  • Pages: 3504
  • Product dimensions: 11.82 (w) x 9.85 (h) x 5.28 (d)

Table of Contents

1 Essentials of Molecular Biology: Basic Principles 3
2 Essentials of Molecular Biology: Genomics and Cancer 17
3 Essentials of Signal Transduction 31
4 Essentials of Immunology 43
5 Molecular Biology of Cancer: Cytogenetics 77
6 Molecular Biology of Cancer: The Cell Cycle 91
7 Molecular Biology of Cancer: Apoplosis 111
8 Molecular Biology of Cancer: Invasion and Metastases 123
9 Biology of Cancer: Angiogenesis 137
10 Etiology of Cancer: Viruses 149
11 Etiology of Cancer: Chemical Factors 179
12 Etiology of Cancer: Physical Factors 195
13 Etiology of Cancer: Cancer Genetics 207
14 Epidemiology of Cancer 219
15 Principles of Cancer Management: Surgical Oncology 253
16 Principles of Cancer Management: Radiation Therapy 265
17 Principles of Cancer Management: Chemotherapy 289
18 Principles of Cancer Management: Biologic Therapy 307
19 Pharmacology of Cancer Chemotherapy 335
20 Pharmacology of Cancer Biotherapeutics 461
21 Clinical Trials in Cancer 521
22 Cancer Prevention: Preventing Tobacco-Related Cancers 549
23 Cancer Prevention: Diet and Chemopreventive Agents 561
24 Cancer Prevention: Role of Surgery in Cancer Prevention 617
25 Cancer Screening 627
26 Cancer Diagnosis: Molecular Pathology 641
27 Cancer Diagnosis: Imaging 659
28 Cancer Diagnosis: Endoscopy 721
29 Specialized Techniques in Cancer Management 739
30 Cancer of the Head and Neck 789
31 Cancer of the Lung 917
32 Neoplasms of the Mediastinum 1019
33 Cancers of the Gastrointestinal Tract 1037
34 Cancers of the Genitourinary System 1343
35 Cancer of the Testis 1491
36 Gynecologic Cancers 1519
37 Cancer of the Breast 1633
38 Cancer of the Endocrine System 1727
39 Sarcomas of the Soft Tissue and Bone 1841
40 Benign and Malignant Mesothelioma 1937
41 Cancer of the Skin 1971
42 Melanoma 2003
43 Neoplasms of the Central Nervous System 2091
44 Cancers of Childhood 2161
45 Lymphomas 2215
46 Leukemias 2389
47 Paraneoplastic Syndromes 2511
48 Cancer of Unknown Primary Site 2537
49 Peritoneal Carcinomatosis 2561
50 Immunosuppression-Related Malignancies 2575
51 Oncologic Emergencies 2609
52 Treatment of Metastatic Cancer 2655
53 Hematopoietic Therapy 2753
54 Infections in the Cancer Patient 2815
55 Adverse Effects of Treatment 2869
56 Supportive Care and Quality of Life 2977
57 Rehabilitation of the Cancer Patient 3089
58 Advanced Practice Nurses and Physician Assistants in Oncology Care 3111
59 Ethical Issues in Oncology and Clinical Trials 3119
60 Information Systems in Oncology 3135
61 Complementary: Alternative, and Unproven Methods of Cancer Treatment 3147
62 Genetic Therapy 3161
63 Cancer Vaccines 3189
64 Image-Guided Surgery 3219
65 Proton Beam Radiation Therapy 3229
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