Cancer Prevention and Management through Exercise and Weight Control

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“ is increasingly clear that cancer is also a disease of inertia. In this book, a broadly multidisciplinary group presents the evidence and provides the recommendations. … The antidote to diseases of inertia is movement — let’s move!”

John Potter, M.D.,Ph.D., from the Foreword

The American Cancer Society estimates that a third of all cancer deaths could be prevented through avoidance of obesity and the rejection of sedentary lifestyles. The World Health Organization also supports this claim. Additionally, these and other organizations now recognize the role that activity can play in improving the quality of life for cancer patients.

Cancer Prevention and Management through Exercise and Weight Control provides us with the support necessary to make a call to action. Itbrings together the contributions of world-class researchers to lay out the evidence and a plan of attack for coping with this crisis. The text begins by focusing on the research methods used in assessing the complex associations between activity, energy balance, and risk and prognosis. In comprehensive literature reviews, the authors consider the role of physical activity in the incidence of individual cancers, then explore the mechanisms that might explain this connection. They continue with a look at the relation between weight and cancer incidence, including a consideration of genetics.

Research is also provided linking physical activity and weight control to a cancer patient’s quality of life and prognosis. The work concludes with ideas on how a plan of action might be implemented at the individual, clinical, and public health levels. It also provides guidance on incorporating exercise and diet recommendations into clinical oncology practice.

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Editorial Reviews

From the Publisher
“… This volume is one of the only of its kind dedicated to helping healthcare providers establish a concrete plan allowing patients to control weight gain through exercise in order to forestall cancer. Expert researchers do an outstanding job delineating this material within a logical framework, looking at ways that physical activity impacts the incidence of cancer in the breast, prostate and colorectal regions … it promotes a step away from drug-based therapies in favor of a more holistic approach to mitigating cancer risks. Bluntly, it’s a message [to] those practicing medicine in the Western world'should pay close and careful attention to. … Recommended to all primary care physicians (in addition to dieticians and nurse practitioners) who serve as a patient’s first-line of defense against disease. In addition, this volume is highly recommended to all Health Science libraries because of its well-detailed and erudite examination of the influence physical activity has on the processes of cancer.”
— John Aiello, in The Electric Review

“… is a collection of 35 chapters organized into 8 sections, each covering different aspects of the complex relationships among body weight, physical activity, cancer incidence, and cancer prognosis. … Each chapter provides a short review and summary of research studies that have addressed a variety of methodological, epidemiological, experimental, and clinical issues related to the prevention and management of different cancers through physical activity and body-weight management. … The organization of the chapters into section is logical, and each chapter includes a list of contents at the beginning. … would be of value to any clinicians who works with patients who have cancer and those who have survived it. It would be an especially helpful resource to anyone who wants to learn more about the current state of knowledge in the relatively new linkage of cancer management, obesity, genetics, and physical activity.”
—Anthony E. Kincaid, Associate Professor, Department of Physical Therapy, Creighton University, Nebraska, in Physical Therapy, Vol. 87, No. 5, p. 615, May 2007

“… The present volume is not a rehash of some long-past symposium. Rather, it contains 35 invited contributions, each with 50-200 references. … In all, this text provides a very thorough, evidence-based summary of current knowledge in a rapidly growing area of research, and it will be an important resource for those working on exercise, obesity and cancer.”
—Roy J. Shephard in Canadian Journal of Applied Physiology, June 2007

"The research presented in McTiernan’s text is truly ground-breaking… Bluntly, it’s a message those practicing medicine in the Western world'should pay close and careful attention to… Recommended to all primary care physicians (in addition to dieticians and nurse practitioners) who serve as a patient’s first-line of defense against disease. In addition, this volume is highly recommended to all Health Science libraries because of its well-detailed and erudite examination of the influence physical activity has on the processes of cancer."

The Electric Review

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Product Details

Table of Contents

Research Methods
Observational Studies and Intervention Trials in Exercise, Diet, and Cancer
Prevention Research: Ross L. Prentice
Physical Activity Measurement: Barbara E. Ainsworth and Karen J. Coleman
Measurement of Body Fat and Energy Balance: Melinda Irwin
Physical Activity and Cancer Incidence
Physical Activity and Cancer Incidence: Breast Cancer: Alpa V. Patel and Leslie Bernstein
Physical Activity and Colorectal Cancer: Martha L. Slattery
Physical Activity and Prostate Cancer Risk: Christine M. Friedenreich
Mechanisms Associating Physical Activity with Cancer Incidence
Physical Activity Effects on Sex Hormones: Anne McTiernan
Exercise and Insulin Resistance: Laura Lewis Frank
Exercise and Immune Function: Catherine M. Wetmore and Cornelia M. Ulrich
Exercise and Prostaglandins: María Elena Martínez
Mechanisms Associating Obesity with Cancer Incidence: Animal Models: Henry J. Thompson, Weiqin Jiang, and Zongjian Zhu
Physical Activity Intervention Studies in Humans: Anne McTiernan
Genetics, Physical Activity, and Cancer: Tuomo Rankinen
Overweight/Obesity and Cancer Incidence
Obesity, Weight Change, and Breast Cancer Incidence: Rachel Ballard–Barbash
Body Size, Obesity, and Colorectal Cancer: Martha L. Slattery
Endogenous Hormone Metabolism and Endometrial Cancer: Rudolf Kaaks and Annekatrin Lukanova
Obesity and Pancreatic Cancer: Dominique S. Michaud and Edward Giovannucci
Obesity and Overweight in Relation to Adenocarcinoma of the Esophagus: Cathrine Hoyo and Marilie D. Gammon
Mechanisms Associating Obesity with Cancer Incidence
Obesity and Sex Hormones: Rudolph Kaaks and Anne McTiernan
Obesity and Insulin Resistance: George Blackburn and Belinda Waltman
Obesity, Cytokines, and Other Inflammatory Markers: Elisa L. Priest and Timothy S. Church
Mechanisms Associating Physical Activity with Cancer Incidence: Animal
Models: Lisa H. Colbert
Genetics, Obesity, and Cancer: Shelley Tworoger and Monica McGrath
Physical Activity and Cancer Prognosis
Quality of Life and Fatigue in Breast Cancer : Kerri Winters-Stone and Anna L. Schwartz
Exercise and Quality of Life in Survivors of Cancer Other Than Breast: Kerry S. Courneya, Kristin L. Campbell, Kristina H. Karvinen, and Aliya B. Ladha
Physical Activity and Physiological Effects Relevant to Prognosis: Page E. Abrahamson and Marilie D. Gammon
Energy Balance and Cancer Prognosis
Breast Cancer: Pamela J. Goodwin
Colon, Prostate, and Other Cancers: Cheryl L. Rock
Physical Activity and Energy Balance: Mikael Fogelholm
Diet and Other Means of Energy Balance Control: David Heber and Susan Bowerman
Population-Based Approaches to Increasing Physical Activity: Fiona Bull
Incorporating Exercise and Diet Recommendations into Primary Care Practice: Nicolaas P. Pronk
Promoting Physical Activity in Cancer Survivors: Anna L. Schwartz and Kerri Winters-Stone
Obesity and Early Stage Breast Cancer Outcome: Rowan T. Chlebowski and Michelle L. Geller
Incorporating Weight Control into Management of Patients with Early
Breast Cancer in the U.K.: Michelle Harvie and Anthony Howell

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