Carcinogenicity and Pesticides: Principles, Issues, and Relationships

Carcinogenicity and Pesticides: Principles, Issues, and Relationships

by Nancy N. Ragsdale
     
 

ISBN-10: 0841217033

ISBN-13: 9780841217034

Pub. Date: 05/05/1989

Publisher: American Chemical Society

This new volume examines the relationship between pesticides and carcinogenicity, presenting some of the current thinking behind the decisions that are made with respect to their use. Progressing from theoretical to practical considerations, this book addresses: mechanisms of carcinogenesis; dietary inhibition of carcinogenesis; biological issues of

Overview

This new volume examines the relationship between pesticides and carcinogenicity, presenting some of the current thinking behind the decisions that are made with respect to their use. Progressing from theoretical to practical considerations, this book addresses: mechanisms of carcinogenesis; dietary inhibition of carcinogenesis; biological issues of extrapolation, and pesticide regulatory issues. Of special interest is a chapter by Bruce Ames, originator of the Ames Test for carcinogenicity, on ranking of possible carcinogenic hazards.

Product Details

ISBN-13:
9780841217034
Publisher:
American Chemical Society
Publication date:
05/05/1989
Series:
ACS Symposium Series, #414
Pages:
237
Product dimensions:
9.00(w) x 6.10(h) x 1.00(d)

Table of Contents

Pesticide Carcinogenicity: Introduction and Background
Pesticide Regulation Related to Carcinogenicity
Pathogenesis of Neoplasia and Influences of Pesticides
Mechanisms of Chemical Carcinogenicity
Critical Events and Determinants in Multistage Skin Carcinogenesis
Pesticide-Induced Modulation of the Immune System
Dietary Inhibition of Cancer
Impact of Chemical Interactions on the Development of Cancer
Biological Issues in Extrapolation
Quantitative Risk Assessment
Role of Structure-Activity Relationship Analysis in Evaluation of Pesticides for Potential Carcinogenicity
Sequential Assessment of Hazard and Risk
Epidemiological Studies of Cancer and Pesticide Exposure
Pesticide Residues and Cancer Causation

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