Cardiac Markers / Edition 2

Cardiac Markers / Edition 2

by Alan H. B. Wu
     
 

ISBN-10: 1588290360

ISBN-13: 9781588290366

Pub. Date: 10/18/2007

Publisher: Springer-Verlag New York, LLC

In this greatly enlarged and thoroughly updated edition of his much praised Cardiac Markers, Alan Wu and his contributors focus on the use of markers in the practice of cardiology and-for the first time-on the use of natriuretic peptides for congestive heart failure. Here, leading international authorities in clinical chemistry and laboratory medicine, cardiology,

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Overview

In this greatly enlarged and thoroughly updated edition of his much praised Cardiac Markers, Alan Wu and his contributors focus on the use of markers in the practice of cardiology and-for the first time-on the use of natriuretic peptides for congestive heart failure. Here, leading international authorities in clinical chemistry and laboratory medicine, cardiology, emergency medicine, and the in vitro diagnostics industry describe the state-of-the-art uses of cardiac markers when treating coronary artery disease, and discuss in detail how they may be optimally used in a clinical setting. Comprehensive and cutting-edge, Cardiac Markers, Second Edition offers physicians a complete guide to the use of cardiac markers in clinical practice and clinical laboratorians a close-up view of the new markers now becoming standard.

Product Details

ISBN-13:
9781588290366
Publisher:
Springer-Verlag New York, LLC
Publication date:
10/18/2007
Series:
Pathology and Laboratory Medicine Series
Edition description:
2nd ed. 2003
Pages:
486
Product dimensions:
10.00(w) x 7.00(h) x 1.06(d)

Table of Contents

Foreword
Preface
Contributors
1Early Detection of Myocardial Necrosis in the Emergency Setting and Utility of Serum Biomarkers in Chest Pain Unit Protocols3
2Management of Acute Coronary Syndromes15
3Evolution of Cardiac Markers in Clinical Trials37
4Assessing Reperfusion and Prognostic Infarct Sizing with Biochemical Markers: Practice and Promise59
5The Use of Cardiac Biomarkers to Detect Myocardial Damage Induced by Chemotherapeutic Agents87
6The Use of Biomarkers to Provide Diagnostic and Prognostic Information Following Cardiac Surgery111
7Cardiac Troponins: Exploiting the Diagnostic Potential of Disease-Induced Protein Modifications125
8Cardiac Troponin Testing in Renal Failure and Skeletal Muscle Disease Patients139
9Cardiac-Specific Troponins Beyond Ischemic Heart Disease149
10Antibody Selection Strategies in Cardiac Troponin Assays173
11Interferences in Immunoassays for Cardiac Troponin187
12Cardiac Marker Measurement by Point-of-Care Testing199
13Standardization of Cardiac Markers213
14Analytical Issues and the Evolution of Cutoff Concentrations for Cardiac Markers231
15Rationale for the Early Clinical Application of Markers of Ischemia in Patients with Suspected Acute Coronary Syndromes245
16Ischemia-Modified Albumin, Free Fatty Acids, Whole Blood Choline, B-Type Natriuretic Peptide, Glycogen Phosphorylase BB, and Cardiac Troponin259
17C-Reactive Protein for Primary Risk Assessment279
18Prognostic Role of Plasma High-Sensitivity C-Reactive Protein Levels in Acute Coronary Syndromes291
19Preanalytic and Analytic Sources of Variations in C-Reactive Protein Measurement305
20Fatty Acid Binding Protein as an Early Plasma Marker of Myocardial Ischemia and Risk Stratification319
21Oxidized Low-Density Lipoprotein and Malondialdehyde-Modified Low-Density Lipoprotein in Patients with Coronary Artery Disease339
22Pathophysiology of Heart Failure351
23B-Type Natriuretic Peptide: Biochemistry and Measurement369
24B-Type Natriuretic Peptide in the Diagnoses and Management of Congestive Heart Failure379
25Monitoring Efficacy of Treatment with Brain Natriuretic Peptide397
26N-Terminal Pro-B-Type Natriuretic Peptide411
27Infectious Diseases in the Etiology of Atherosclerosis and Acute Coronary Syndromes: Focus on Chlamydia pneumoniae427
28Polymorphisms Related to Acute Coronary Syndromes and Heart Failure: Potential Targets for Pharmacogenomics439
Index461

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