Casarett and Doull's Toxicology: The Basic Science of Poisons / Edition 6

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2001 Hardcover New *****PLEASE NOTE: This item is shipping from an authorized seller in Europe. In the event that a return is necessary, you will be able to return your item ... within the US. To learn more about our European sellers and policies see the BookQuest FAQ section***** Read more Show Less

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Overview

The most complete, trusted reference text covering the full span of medical toxicology

A Doody's Core Title ESSENTIAL PURCHASE!

"This reference stands alone as the basic text in the field of toxicology. This authoritative reference is written by many distinguished professionals in the field, and offers clear, concise descriptions of the key concepts in toxicology. It is extensive and complete, covering a broad range of topics in sufficient detail. Both as a reference and as an educational tool, this book exceeds its goal of serving as a reference for toxicologists, other scientists, and students of the discipline. 3 Stars."—Doody's Review Service

Long established as the gold standard in the field, Casarett & Doull's Toxicology equips you with an unsurpassed understanding of modern toxicology, including the principles, concepts, mechanisms, and modes of thought that are the foundation of the discipline. The new seventh edition features is updated throughout and includes many new contributors and new content on chemical terrorism.

Curtis D. Klaasen, PhD, University Distinguished Professor and Chair, Kansas University School of Medicine; Kansas City, Kansas.

The book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Kim A Anderson, PhD (Oregon State University)
Description: This 6th edition of a classic toxicology text picks up where the last edition left off, keeping all the fundamental pedagogically important components while adding current research toxicology. The addition of more risk assessment is an excellent enhancement to this edition. The previous edition was published in 1996.
Purpose: The purpose is to serve primarily as a text for graduate courses in toxicology. To this end the book hits the bulls-eye. Pedagogically, the book is a cornerstone to toxicology students. It is "must-have" for all students in toxicology or working in toxicologically related fields. The book meets the authors' objectives.
Audience: The authors have prepared the book for students in toxicology. It is also an excellent desk reference for researchers working in fields related to toxicology. The authors are all highly recognized in their fields.
Features: The book covers the basic components of toxicology, from general principles, modes of action, target organs, and chemical-specific toxicity. It concludes with environmental toxicology and applications of toxicology. The environmental toxicology chapter is composed of two sections covering air pollution and ecotoxicology. In the interest of keeping the book a manageable size, other areas of pollution may have been left out, but many users would not necessarily rank air pollution over other forms of pollution (water, etc.). In the application of toxicology chapter, the regulatory section could use a better description of quality control and quality assurance and how this integrates with good laboratory practices (GLP). Many toxicology students will work at some point on a GLP study. Most notably, the brief discussion is not well referenced so the students are not led to other sources of information.
Assessment: This book is now an established classic in the field of toxicology. In the time between the 5th and 6th edition, there have been significant advances in research that warrant this edition. When it comes to completeness, there really is no comparable book on the market. The down side is that the book now is getting so large than it may soon become impractical for students to carry it around to classes. An option that one might consider is to get the book on CD, since many students bring a computer to class as much or more than their books.
Niko Keys
This is a new edition of a major textbook on the basic science of toxicology intended for both students and practitioners. Its emphasis is on mechanisms of toxicity. The last edition was published in 1991. It provides information on the many facets of toxicology, especially on the principles, concepts, and modes of thought that are the foundation of the discipline. This book is written for graduate courses in toxicology. In addition, scientists from other disciplines may find relevant sections. This is an accurate target audience, in my opinion. The illustrations are well done and absolutely necessary. The text is extensively referenced and up-to-date. The book is neat in appearance. This continues to be the premier reference book on the basic science of toxicology. The new edition is a timely update of a very useful book.
Booknews
**** The fourth edition (1991, ed. by Mary O. Amdur et al.) is cited in Brandon-Hill. A text for, or an adjunct to, graduate courses in toxicology, providing information on the principles, concepts, and modes of thought that are the foundation of the discipline. The present edition is revised and updated to reflect the marked progress in toxicology during this decade. It adds three new chapters, on toxicokinetics, mechanisms of toxicity, and toxic responses of the endocrine system, as well as an appendix on recommended limits for exposure to chemicals. Annotation c. Book News, Inc., Portland, OR (booknews.com)

3 Stars from Doody
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Product Details

  • ISBN-13: 9780071347211
  • Publisher: McGraw-Hill Companies, The
  • Publication date: 7/27/2001
  • Edition description: Older Edition
  • Edition number: 6
  • Pages: 1275
  • Product dimensions: 8.92 (w) x 11.22 (h) x 2.03 (d)

Meet the Author

Curtis D. Klaasen, PhD, University Distinguished Professor and Chair, Kansas University School of Medicine; Kansas City, Kansas.

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Table of Contents

Contributors
Preface
Preface to the First Edition
Unit 1 General Principles of Toxicology
1 History and Scope of Toxicology
2 Principles of Toxicology
3 Mechanisms of Toxicity
4 Risk Assessment
Unit 2 Disposition of Toxicants
5 Absorption, Distribution, and Excretion to Toxicants
6 Biotransformation of Xenobiotics
7 Toxicokinetics
Unit 3 Non-Organ-Directed Toxicity
8 Chemical Carcinogenesis
9 Genetic Toxicology
10 Development Toxicology
Unit 4 Target Organ Toxicity
11 Toxic Responses of the Blood
12 Toxic Responses of the Immune System
13 Toxic Responses of the Liver
14 Toxic Responses of the Kidney
15 Toxic Responses of the Respiratory System
16 Toxic Responses of the Nervous System
17 Toxic Responses of the Ocular and Visual System
18 Toxic Responses of the Heart and Vascular Systems
19 Toxic Responses of the Skin
20 Toxic Responses of the Reproductive System
21 Toxic Responses of the Endocrine System
Unit 5 Toxic Agents
22 Toxic Effects of Pesticides
23 Toxic Effects of Metals
24 Toxic Effects of Solvents and Vapors
25 Toxic Effects of Radiation and Radioactive Materials
26 Toxic Effects of Terrestrial Animal Venoms and Poisons
27 Toxic Effects of Plants
Unit 6 Environmental Toxicology
28 Air Pollution
29 Ecotoxicology
Unit 7 Applications of Toxicology
30 Food Toxicology
31 Analytic/Forensic Toxicology
32 Clinical Toxicology
33 Occupational Toxicology
34 Regulatory Toxicology
App Recommended Limits for Occupational Exposure to Chemicals
Index
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