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Doody's Review ServiceReviewer: Kim A Anderson, PhD (Oregon State University)
Description: This 6th edition of a classic toxicology text picks up where the last edition left off, keeping all the fundamental pedagogically important components while adding current research toxicology. The addition of more risk assessment is an excellent enhancement to this edition. The previous edition was published in 1996.
Purpose: The purpose is to serve primarily as a text for graduate courses in toxicology. To this end the book hits the bulls-eye. Pedagogically, the book is a cornerstone to toxicology students. It is "must-have" for all students in toxicology or working in toxicologically related fields. The book meets the authors' objectives.
Audience: The authors have prepared the book for students in toxicology. It is also an excellent desk reference for researchers working in fields related to toxicology. The authors are all highly recognized in their fields.
Features: The book covers the basic components of toxicology, from general principles, modes of action, target organs, and chemical-specific toxicity. It concludes with environmental toxicology and applications of toxicology. The environmental toxicology chapter is composed of two sections covering air pollution and ecotoxicology. In the interest of keeping the book a manageable size, other areas of pollution may have been left out, but many users would not necessarily rank air pollution over other forms of pollution (water, etc.). In the application of toxicology chapter, the regulatory section could use a better description of quality control and quality assurance and how this integrates with good laboratory practices (GLP). Many toxicology students will work at some point on a GLP study. Most notably, the brief discussion is not well referenced so the students are not led to other sources of information.
Assessment: This book is now an established classic in the field of toxicology. In the time between the 5th and 6th edition, there have been significant advances in research that warrant this edition. When it comes to completeness, there really is no comparable book on the market. The down side is that the book now is getting so large than it may soon become impractical for students to carry it around to classes. An option that one might consider is to get the book on CD, since many students bring a computer to class as much or more than their books.