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Doody's Review ServiceReviewer: Kara E Warner, BA, MS (Oregon State University)
Description: This book is adapted from Casarett and Doull's Toxicology: The Basic Science of Poisons, 6th edition (McGraw-Hill, 2001), and, as promised, it is highly readable and contains helpful illustrations and tables. The content is clearly organized and flows from mechanisms of toxicity to target organ toxicity, and on to specific toxic agents and applications of the study of toxicology.
Purpose: The goal is to help the reader achieve an understanding of the mechanisms of toxicity in target tissues and the agents involved. The book is to serve as a more concise and readable counterpart to its more text-heavy source. It is definitely more approachable, and does serve as an appropriate introduction to toxicology, thereby meeting the authors' goals.
Audience: The book is written for undergraduate and graduate students (according to the author), and it is appropriate for this level. The editors are highly credible authorities in the field.
Features: This book covers an introduction to mechanisms and target sites of toxic agents, classes of toxic substances, and a review of the applications and careers involved in toxicological studies. It is very readable, and contains an adequate amount of figures (although a bit lacking in some chapters, but great in others) and tables. The chapters dealing with target organ toxicity are especially well organized. The appendix is extremely helpful and essential. The chapters give key points that perhaps should be listed at the end to allow the reader to review that section's content. The review questions at the end of the book are helpful and relevant, but should be placed at the end of each chapter to test the reader's absorption of the pertinent material. Specific case studies (separated from the text) would be an excellent way of providing examples of mechanisms or applications of toxicity, and would help engage the reader.
Assessment: This book serves as a highly useful introduction to toxicology, and I would recommend it to students entering the field before the main textbook.