Casarett & Doull's Essentials of Toxicology, Second Edition / Edition 2

Paperback (Print)
Rent from
(Save 75%)
Est. Return Date: 07/28/2015
Buy Used
Buy Used from
(Save 41%)
Item is in good condition but packaging may have signs of shelf wear/aging or torn packaging.
Condition: Used – Good details
Used and New from Other Sellers
Used and New from Other Sellers
from $33.40
Usually ships in 1-2 business days
(Save 62%)
Other sellers (Paperback)
  • All (22) from $33.40   
  • New (9) from $50.91   
  • Used (13) from $33.40   


The most concise and authoritative introduction to the principles of toxicology and how poisons affect the human body – now in full color

A Doody's Core Title ESSENTIAL PURCHASE for 2011!

Casarett & Doull’s Essentials of Toxicology is an easy-to-absorb distillation of the field’s gold-standard text Casarett & Doull’s Toxicology: The Basic Science of Poisons. Presented in full color for the first time, the book combines an accessible and engaging approach with coverage of essential introductory concepts to provide you with a solid grounding in basic and medical toxicology. Succinct, yet comprehensive, the text covers essential principles, toxicokinetics, how toxic effects are passed on to succeeding generations, how each body system responds to poisons, and the specific effects of a wide range of toxic agents – from pesticides to radiation.


  • A complete basic overview of poisons and their clinical management
  • Reflects the expertise of more than fifty renowned contributors
  • A summary of important points is included at the beginning of each chapter and multiple-choice review questions appear at the conclusion
  • Important chapters on forefront topics such as Analytic/Forensic Toxicology, Clinical Toxicology, Occupational Toxicology, Air Pollution, and Ecotoxicology

Condensed Table of Contents: General Principles of Toxicology, Disposition of Toxicants, Nonorgan-Directed Toxicity, Target Organ Toxicity, Toxic Agents, Environmental Toxicology, Applications of Toxicology.

Read More Show Less

Product Details

  • ISBN-13: 9780071622400
  • Publisher: McGraw-Hill Professional Publishing
  • Publication date: 7/12/2010
  • Edition description: New Edition
  • Edition number: 2
  • Pages: 472
  • Sales rank: 232,899
  • Product dimensions: 8.78 (w) x 11.08 (h) x 0.66 (d)

Meet the Author

Curtis D. Klaassen, PhD

University Distinguished Professor and Chair

Department of Pharmacology, Toxicology, and Therapeutics

University of Kansas Medical Center

Kansas City, KS

John B. Watkins, III, PhD

Assistant Dean and Director

Professor of Pharmacology and Toxicology

Medical Sciences Program

Indiana University School of Medicine

Bloomington, IN

Read More Show Less

Table of Contents




1 History and Scope of Toxicology Michael A. Gallo Gallo, Michael A. 1

2 Principles of Toxicology Steven G. Gilbert Gilbert, Steven G. 5

3 Mechanisms of Toxicity Zoltan Gregus Gregus, Zoltan 21

4 Risk Assessment Gilbert S. Omenn Omenn, Gilbert S. 47


5 Absorption, Distribution, and Excretion of Toxicants Lois D. Lehman-McKeeman Lehman-McKeeman, Lois D. 57

6 Biotransformation of Xenobiotics Brian W. Ogilvie Ogilvie, Brian W. 71

7 Toxicokinetics Danny D. Shen Shen, Danny D. 99


8 Chemical Carcinogenesis Lisa M. Kamendulis Kamendulis, Lisa M. 109

9 Genetic Toxicology George R. Hoffmann Hoffmann, George R. 123

10 Developmental Toxicology Robert J. Kavlock Kavlock, Robert J. 135


11 Toxic Responses of the Blood John T. Brandt Brandt, John T. 147

12 Toxic Responses of the Immune System Michael P. Holsapple Holsapple, Michael P. 161

13 Toxic Responses of the Liver Hartmut Jaeschke Jaeschke, Hartmut 177

14 Toxic Responses of the Kidney Rick G. Schnellmann Schnellmann, Rick G. 191

15 Toxic Responses of the Respiratory System Jerold A. Last Last, Jerold A. 203

16 Toxic Responses of the Nervous System Martin A. Philbert Philbert, Martin A. 217

17 Toxic Responses of the Ocular and Visual System William K. Boyes Boyes, William K. 233

18 Toxic Responses of the Heart and Vascular System Y. James Kang Kang, Y. James 247

19 Toxic Responses of the Skin Theodora M. Mauro Mauro, Theodora M. 267

20 Toxic Responses of the Reproductive System L. Earl Gray Jr Gray, L. Earl, Jr 279

21 Toxic Responses of the Endocrine System Charles C. Capen Capen, Charles C. 293


22 Toxic Effects of Pesticides Lucio G. Costa Costa, Lucio G. 309

23 Toxic Effects of Metals Michael P. Waalkes Waalkes, Michael P. 323

24 Toxic Effects of Solvents and Vapors D. Alan Warren Warren, D. Alan 335

25 Toxic Effects of Radiation and Radioactive Materials Naomi H. Harley Harley, Naomi H. 347

26 Toxic Effects of Terrestrial Animal Venoms and Poisons John B. Watkins III Watkins, John B., III 359

27 Toxic Effects of Plants, Fungi, and Algae Stata Norton Norton, Stata 369

UNIT 6 Environmental Toxicology 377

28 Air Pollution Daniel L. Costa Costa, Daniel L. 377

29 Ecotoxicology Michael C. Newman Newman, Michael C. 389


30 Food Toxicology George A. Burdock Burdock, George A. 399

31 Analytic/Forensic Toxicology Alphonse Poklis Poklis, Alphonse 409

32 Clinical Toxicology Louis R. Cantilena Jr Cantilena, Louis R., Jr 415

33 Occupational Toxicology Peter S. Thorne Thorne, Peter S. 425

Answers to Chapter Questions 435

Index 439

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)