Cell and Molecular Biology of the Testis / Edition 1

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Overview

This book is a comprehensive, multi-authored work on the structure and function of the mammalian testis. The approach emphasizes gene expression, translation and production of specific gene products and the cellular and molecular regulation of these fundamental processes. Rather than provide a global survey of all aspects of male reproduction, this book stresses specific mechanisms that underscore the structure and function of the testis. It explains old and new concepts from a cellular and molecular perspective. This novel approach allows the authors to forge links between cell and molecular biology and well-established aspects of spermatogenesis and steroidogenesis. The result is a well-focused, comprehensive, and synthetic analysis of testicular biology.

This book contains black-and-white illustrations.

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Editorial Reviews

Doody's Review Service
Reviewer: Alvin Telser, PhD (Northwestern University Feinberg School of Medicine)
Description: This is a comprehensive and current treatise on the cell and molecular biology of the mammalian testis. It is well written, well edited, and of high quality both from a content and physical point of view.
Purpose: The book is intended to combine cellular, molecular, genetic, physiologic, and developmental facts and concepts about the testes for workers in the field and for those who may need an authoritative reference or who may wish to learn about this aspect of reproductive biology. These objectives are achieved to a significant degree in this monograph.
Audience: The book is written for researchers in this field and for those who may wish to learn more about the field. There is a high probability that the book will become the major reference in the cell and molecular biology of the testes for the next several years.
Features: The book has no special distinctive features. The graphs and line drawings are clear, accurate, and easy to interpret. The smaller number of light and electron micrographs are of a good, but not exceptional, quality. Most chapters have an appropriate number of illustrations; others might benefit from a greater number of diagrams.
Assessment: This is an excellent book that is likely to become the standard reference in its field during the next five years or so. It combines a wide range of contemporary knowledge about and approaches to the biology of the testes. Libraries should find this monograph to be a valuable addition to their collection on modern approaches to and knowledge of traditional areas of human biology.
Alvin Telser
This is a comprehensive and current treatise on the cell and molecular biology of the mammalian testis. It is well written, well edited, and of high quality both from a content and physical point of view. "The book is intended to combine cellular, molecular, genetic, physiologic, and developmental facts and concepts about the testes for workers in the field and for those who may need an authoritative reference or who may wish to learn about this aspect of reproductive biology. These objectives are achieved to a significant degree in this monograph. "The book is written for researchers in this field and for those who may wish to learn more about the field. There is a high probability that the book will become the major reference in the cell and molecular biology of the testes for the next several years. "The book has no special distinctive features. The graphs and line drawings are clear, accurate, and easy to interpret. The smaller number of light and electron micrographs are of a good, but not exceptional, quality. Most chapters have an appropriate number of illustrations; others might benefit from a greater number of diagrams. "This is an excellent book that is likely to become the standard reference in its field during the next five years or so. It combines a wide range of contemporary knowledge about and approaches to the biology of the testes. Libraries should find this monograph to be a valuable addition to their collection on modern approaches to and knowledge of traditional areas of human biology.

5 Stars! from Doody
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Product Details

  • ISBN-13: 9780195062694
  • Publisher: Oxford University Press, USA
  • Publication date: 1/1/1993
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 512
  • Product dimensions: 7.63 (w) x 12.63 (h) x 1.59 (d)

Table of Contents

Contributors
1 Cell Biology of Testicular Development in the Fetus and Neonate 3
2 Molecular Genetics of the Human and Mouse Y-Chromosome 43
3 Development of the Germ Cell 58
4 Genetic Control of Spermatogenesis and Steroidogenesis 90
5 Mullerian Inhibiting Substance 108
6 Design and Function of the Microcirculation 127
7 Leydig Cell: Structure and Function 137
8 Regulation of Spermatogenesis in the Adult Mammal: Gonadotropins and Androgens 166
9 The Cell Biology of the Sertoli Cell 189
10 Inhibin and Inhibin-Related Proteins 220
11 The Seminiferous Tubular Microenvironment 238
12 Spermatogonial Stem Cells 266
13 The Process of Meiosis 296
14 Cell Biology of Mammalian Spermiogenesis 332
15 Cellular Interactions in the Seminiferous Epithelium 377
16 Gene Expression During Male Germ Cell Development 400
17 Patterns of Expression and Potential Functions of Cellular Oncogenes and Heat Shock Protein Genes During Germ Cell Developments 433
18 Sperm Cell Surface Proteins of Testicular Origin: Expression and Localization in the Testis and Beyond 452
19 Regulation of Testicular Autoimmune Disease 474
Index 491
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