Cellular and Molecular Immunology, Updated Edition: With STUDENT CONSULT Online Access / Edition 6

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Overview

Cellular and Molecular Immunology, by Abul K. Abbas, MBBS, Andrew H. Lichtman, MD, PhD and Shiv Pillai, MD, offers an exceptionally lucid guide to the latest immunology concepts! Readers worldwide have appreciated the book's in-depth yet straightforward, richly illustrated approach to this complex subject. Now, sweeping updates incorporate the latest discoveries about innate immunity, the organization of lymphoid organs, and many other cutting-edge topics. Plus, online access via Student Consult makes this an even more powerful learning resource!

• Clearly explains the experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels—and the conclusions that can be drawn from those observations.
• Highlights the implications of immunologic science for the management of human disease, emphasizing the clinical relevance of the material.
• Offers access to the complete contents of the book online at www.studentconsult.com to help students prepare for coursework and exams.

• Innate immunity chapter has been increased and moved to the beginning of the book to reflect how this area is newly recognized as a critical part of immunology.
• New material has been added on:

• recognition of microbial products by cytoplasmic and membrane sensors
• intricate organization of lymphoid tissues
• functional heterogeneity of subsets of dendritic cells and lymphocytes
• roles of regulatory cells and inhibitory pathways in immune regulation.

• Provides a wealth of excellent full-color photographs and illustrations that enable you to visualize immunologic processes quickly.
• Includes highlighted "take-home messages" that make it easy to review key information.
• Features instructor resources such including an Image Collection and new 250 question Test Bank on Evolve

The book contains predominantly color illustrations, with some black-and-white illustrations.

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Editorial Reviews

From the Publisher
"Immunology is a hard subject. This book makes it easy! There are many drawings, and this really makes it easier to understand. Also, the authors have made a genius thing by starting the paragraphs with a bolded text giving just the information one need to get an overview. The summaries are good, giving the reader a possibility to get familiar with the chapter before reading it." Medical Student, University of Bergen, Norway

"What we know about the immune system is constantly changing and books are often lacking new details even before they are printed. Dr. Abbas, as senior editor, has made a serious attempt to incorporate this growing body of knowledge in this book. Those who already own the sixth edition might not want to invest in this update, but for those working with the 5th edition or earlier, this may be a good time to upgrade.

Although it is intended for a basic immunology course for medical students, graduate students and dental students could easily make good use of it.

As always Dr. Abbas and his coeditors have provided an excellent source of information about the immune system. The book is readable and the figures illustrate concepts very nicely." - Marion C. Cohen, PhD(University of Medicine and Dentistry of New Jersey-NJMS), Doody’s Review

Doody's Review Service
Reviewer: Marion C. Cohen, PhD (SUNY Downstate Medical Center)
Description: This is an updated version of a well-received basic immunologic textbook. Both text and figures have been significantly refined over the years since the first edition was published. The previous edition was published in 2007.
Purpose: What we know about the immune system is constantly changing and books are often lacking new details even before they are printed. Dr. Abbas, as senior editor, has made a serious attempt to incorporate this growing body of knowledge in this book. Those who already own the sixth edition might not want to invest in this update, but for those working with the 5th edition or earlier, this may be a good time to upgrade.
Audience: Although it is intended for a basic immunology course for medical students, graduate students and dental students could easily make good use of it. Moreover, physicians who are less than familiar with current immunological concepts would find it a helpful resource.
Features: The book covers the subjects that are considered to be part of a basic immunology course. Each section clearly identifies concepts that are considered "take-home messages." Information designated as "in depth" is found in clearly marked boxes. The first-rate illustrations are available to instructors to use in their presentations. Important points are presented in summary form at the end of each chapter. Purchase of the book entitles the buyer to online access to Student Consult. The only area that is lacking depth is the information on the mucosal immune system, which has recently started to receive greater attention. No doubt the next edition will present greater detail on this aspect of immunology.
Assessment: As always Dr. Abbas and his coeditors have provided an excellent source of information about the immune system. The book is readable and the figures illustrate concepts very nicely. Several other textbooks convey the same sort of information and it is not always clear why a course director would choose one over another. Nonetheless, once again, this one is a winner.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9781416031239
  • Publisher: Elsevier Health Sciences
  • Publication date: 5/26/2009
  • Edition description: Older Edition
  • Edition number: 6
  • Pages: 576
  • Product dimensions: 8.60 (w) x 10.80 (h) x 0.90 (d)

Meet the Author

Abul K. Abbas, MBBS, Chairman Department of Pathology, UCSF School of Medicine,San Francisco, CA

Andrew H. Lichtman, MD, PhD, Associate Professor of Pathology, Harvard Medical School and Brigham and Women's Hospital, Boston, MA

Jordan S. Pober, MD, PhD, Professor of Pathology, Immunobiology, and Dermatology, Yale University School of Medicine, New Haven, CT

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Table of Contents

SECTION I INTRODUCTION TO IMMUNOLOGY 1
CHAPTER 1 GENERAL PROPERTIES OF IMMUNE RESPONSES 3
CHAPTER 2 CELLS AND TISSUES OF THE IMMUNE SYSTEM 14
SECTION II LYMPHOCYTE SPECIFICITY AND ACTIVATION 31
CHAPTER 3 ANTIBODIES AND ANTIGENS 33
CHAPTER 4 MATURATION OF B LYMPHOCYTES AND EXPRESSION OF IMMUNOGLOBULIN GENES 65
CHAPTER 5 THE MAJOR HISTOCOMPATIBILITY COMPLEX 96
CHAPTER 6 ANTIGEN PROCESSING AND PRESENTATION TO T LYMPHOCYTES 115
CHAPTER 7 MOLECULAR BASIS OF T CELL ANTIGEN RECOGNITION AND ACTIVATION 136
CHAPTER 8 T CELL MATURATION IN THE THYMUS 166
CHAPTER 9 B CELL ACTIVATION AND ANTIBODY PRODUCTION 187
CHAPTER 10 REGULATION OF IMMUNE RESPONSES 205
CHAPTER 11 FUNCTIONAL ANATOMY OF LOCAL AND SYSTEMIC IMMUNE RESPONSES 222
SECTION III EFFECTOR MECHANISMS OF IMMUNE RESPONSES 237
CHAPTER 12 CYTOKINES 239
CHAPTER 13 EFFECTOR MECHANISMS OF T CELL-MEDIATED IMMUNE REACTIONS 261
CHAPTER 14 EFFECTOR MECHANISMS OF IMMUNOGLOBULIN E-INITIATED IMMUNE REACTIONS 278
CHAPTER 15 THE COMPLEMENT SYSTEM 293
SECTION IV IMMUNITY IN DEFENSE AND DISEASE 317
CHAPTER 16 IMMUNITY TO MICROBES 319
CHAPTER 17 IMMUNE RESPONSES TO TISSUE TRANSPLANTS 337
CHAPTER 18 IMMUNITY TO TUMORS 356
CHAPTER 19 SELF-TOLERANCE AND AUTOIMMUNITY 376
CHAPTER 20 IMMUNE-MEDIATED TISSUE INJURY AND DISEASE 393
CHAPTER 21 CONGENITAL AND ACQUIRED IMMUNODEFICIENCIES 409
APPENDIX PRINCIPAL FEATURES OF KNOWN CD MOLECULES 431
INDEX 437
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