Cellular and Molecular Regulation of Testicular Cells / Edition 1

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This volume contains the proceedings of the Symposium on Cellular and Molecular Regulation of Testicular Cells, held from March 30 - April 1, 1995 in Raleigh, North Carolina. Written and edited by eminent international experts, the papers herein cover: molecular dissection of the cell cycle, regulation of germ cell differentiation, cell-cell interactions in the seminiferous epithelium, macromolecules and organelles unique to germ cells, regulation of meiotic events in spermatogenesis, androgen action and production, transport mechanisms in spermatogenesis, cell and molecular biology of the leydig cell, regulation of steroidogenesis.

The book contains black-and-white illustrations.

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Product Details

  • ISBN-13: 9780387946481
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 1/28/1996
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 371

Table of Contents

1 Evolution of the Testis Workshop: 1972-1995 1
2 From Start to S Phase: Early Events in the Yeast Cell Cycle 11
3 Oocyte Activation and Passage Through the Meiotic Cell Cycle in Xenopus Laevis 27
4 Establishment of Meiotic Germ-Cell Lines and Their Use to Study Spermatogenesis in Vitro 45
5 Mouse Spermatocyte Chromosome Cores: Protein and DNA Organization 65
6 CREMt Activates the Spermatid-Specific RT7 and Mouse Protamine 1 Promoters 73
7 Role of Vitamin A in Male Germ-Cell Development 83
8 Alternative Forms and Functions of the c-kit Receptor and Its Ligand During Spermatogenesis
9 The IGF-H/Cation-Independent Mannose 6-Phosphate Receptor Mediates Changes in Spermatogenic Cell Gene Expression 111
10 Testis-Specific Gene Transcription 127
11 Molecular and Cellular Biology of Novel Cytoskeletal Proteins in Spermatozoa 135
12 Promoter Analysis of Male Germ-Cell-Specific Genes: Nuclear Transition Protein-1 and Histone H1t 167
13 Androgen Receptor Distribution in the Testis 189
14 Testicular Androgen Receptor Protein: Distribution and Control of Expression 213
15 Role of Carrier Proteins in the Movement and Metabolism of Retinoids in the Seminiferous Tubule 231
16 Transport Mechanisms for Endocrine and Paracrine Factors in the Testis 249
17 Hormonal Regulation of the Differentiation of Leydig Cells from Mesenchymal-Like Progenitors During Puberty 263
18 Developmental and cAMP-Dependent Regulation of CYP17 Gene Expression 277
19 A Cell-Specific Nuclear Receptor Plays Essential Roles in Reproductive Function 289
20 Activating Mutations of the Luteinizing Hormone Receptor Gene in Familial Testotoxicosis 297
21 Characterization of the Protein Responsible for the Acute Regulation of Steroidogenesis in Mouse Leydig Tumor Cells 311
22 Diazepam-Binding Inhibitor and Peripheral Benzodiazepine Receptors: Role in Steroid Biosynthesis 337
Author Index 357
Subject Index 359
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