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Cellular Therapy

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The use of cells for the treatment of a variety of diseases is no longer a dream. Today, blood transfusion, bone marrow transplantation, the use of ex vivo cultured skin in wound healing, and peripheral stem cell transplantation, including the ex vivo expansion of hematopoietic stem cells after high-dose chemo/radiation therapy, are routine. This high standard of knowledge and skills in cell transplantation might also result in tackling hitherto untreatable diseases. Organ transplantation is presently the only ...

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Overview

The use of cells for the treatment of a variety of diseases is no longer a dream. Today, blood transfusion, bone marrow transplantation, the use of ex vivo cultured skin in wound healing, and peripheral stem cell transplantation, including the ex vivo expansion of hematopoietic stem cells after high-dose chemo/radiation therapy, are routine. This high standard of knowledge and skills in cell transplantation might also result in tackling hitherto untreatable diseases. Organ transplantation is presently the only life-saving treatment for a variety of conditions. Important findings in cell and molecular biology could make cellular therapy an alternative to organ transplantation in certain diseases.

The book contains black-and-white illustrations.

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Product Details

Table of Contents

1 Somatic Gene Therapy in Cancer 1
2 Placental Blood: New Options in Hematopoietic Stem Cell Transplantation 25
3 Recent Developments in the Ex Vivo Manipulation of Hematopoietic Cells from Bone Marrow and Blood 37
4 Monocyte-Derived Cells in Adoptive Immunotherapy of Cancer: Facts and Perspectives 55
5 The Immunological Basis for the Development of Tumor Cell and Peptide-Based Vaccines for Treatment of Patients with Renal Cell Carcinoma 75
6 Transplantation of Isolated Islets of Langerhans as Treatment of Diabetes Mellitus 87
7 Potential Use of Marrow Stromal Cells for Therapy of Osteogenesis Imperfecta and Osteoporosis 111
8 Neuronal Modulation of the Immune Response in Nervous Tissue: Implications for Neurodegenerative and Autoimmune Diseases 119
9 Transplantation of Dopamine-Synthesizing Cells in Parkinson's Disease: Experimental Data and Clinical Application 129
10 Repairing CNS Demyelination by Glial Cell Transplantation 145
11 Monitoring of Suicide Gene Therapy with Positron Emission Tomography 159
Subject Index 177
Previous Volumes Published in this Series 179
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