cGMP: Generators, Effectors and Therapeutic Implications / Edition 1

cGMP: Generators, Effectors and Therapeutic Implications / Edition 1

by Harald H. H. W. Schmidt
     
 

ISBN-10: 3642088481

ISBN-13: 9783642088483

Pub. Date: 11/23/2010

Publisher: Springer Berlin Heidelberg

After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of

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Overview

After the discovery of endogenous NO formation in the late '80s and the 1998 Nobel Prize in Physiology or Medicine, many researchers and physicians again became interested in the NO/sGC interaction and cGMP-dependent signaling. This book is an enthusiastic celebration of cyclic guanosine monophosphate (cGMP) and amply illustrates the importance of this field of science to patients and the way in which the field has evolved. It is exclusively devoted to this exciting and important signaling molecule, addressing all recent advances in understanding guanylate cyclase regulation, NO/sGC interactions, cGMP effector mechanisms and their pathophysiological and pharmacological implications. Particular attention will also be given to clinical applications of the novel cGMP-elevating drugs which are on the horizon, thus spanning the continuum from basic science to clinic.

Product Details

ISBN-13:
9783642088483
Publisher:
Springer Berlin Heidelberg
Publication date:
11/23/2010
Series:
Handbook of Experimental Pharmacology Series, #191
Edition description:
Softcover reprint of hardcover 1st ed. 2009
Pages:
583
Product dimensions:
6.10(w) x 9.25(h) x 0.05(d)

Related Subjects

Table of Contents

Preface.- Part I: Basic Generators and Effectors.- Part II: Pharmacology of cGMP.- Part III: Clinical Applications.

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