The Changing Nervous System: Neurobehavioral Consequences of Early Brain Disorders [NOOK Book]

Overview

This book provides an integrated review of current research on neural plasticity and reorganization after early cerebral insults. Addressing both animal studies and a variety of diverse clinical populations, including children with congenital brain malformations, focal lesions, autism, and pervasive developmental disorders, this book summarizes many of the major advances on neural plasticity made in these areas over the past several years. Characterized by a broad historical perspective including contributions ...

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The Changing Nervous System: Neurobehavioral Consequences of Early Brain Disorders

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Overview

This book provides an integrated review of current research on neural plasticity and reorganization after early cerebral insults. Addressing both animal studies and a variety of diverse clinical populations, including children with congenital brain malformations, focal lesions, autism, and pervasive developmental disorders, this book summarizes many of the major advances on neural plasticity made in these areas over the past several years. Characterized by a broad historical perspective including contributions from some of the earliest researchers on environmental factors and brain organization, the book advances the reader form the laboratory to application in several human populations. Many of the components of the book explicitly address relationships of animal and human models, showing that the laboratory and the clinic are overlapping settings, not isolated chambers as they are often perceived. The understanding of neural plasticity and both biological and environmental factors that influence brain reorganization after early cerebral insult has major implications for treatment. The book outlines many of the potential applications for treatment of early brain disorders. The contributors include basic neuroscientists, cognitive neuroscientists, and clinician-researchers who work together to bridge gaps among disciplines. The book should facilitate collaborative research and applications in the critical areas of neural plasticity and brain reorganization. Advancement of knowledge of factors that prevent and enhance brain reorganization after early cerebral insult is a key to unraveling the mysteries of the developmental disorders characteristic of children and which influence their development through adulthood.

"...an integrated review of current research on neural plasticity and reorganization after early cerebral insults ...outlines many potential applications for treatment of early brain disorders."

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Product Details

  • ISBN-13: 9780198028451
  • Publisher: NetLibrary, Incorporated
  • Publication date: 7/15/1999
  • Sold by: Barnes & Noble
  • Format: eBook
  • File size: 5 MB

Meet the Author

National Institute of Neurological Disorders and Stroke

University of Texas Health Sciences Center, Houston

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Table of Contents

Contributors
Pt. I Shaping the Central Nervous System
1 Wiring the Brain: Activity-Dependent and Activity-Independent Development of Synaptic Circuits 3
2 Effects of Differential Experience on Brain and Cognition Throughout the Life Span 25
3 Experience and Plasticity in Brain Structure: Possible Implications of Basic Research Findings for Developmental Disorders 57
Pt. II Mechanisms of Reorganization
4 Structural Changes Underlying Long-Term Memory 73
5 Role of Intrinsic Circuitry in Motor Cortex Plasticity 97
6 Immature Visual Cortex Lesions: Global Rewiring, Neural Adaptations, and Behavioral Sparing 114
Pt. III Neurodevelopmental Course of Early Brain Disorders
7 Role of the Corpus Callosum in the Cognitive Development of Children with Congenital Brain Malformations 149
8 Functional Consequences of Congenital Cerebellar Dysmorphologies and Acquired Cerebellar Lesions of Childhood 172
9 Recovery from Acquired Reading and Naming Deficits Following Focal Cerebral Lesions 199
10 Plasticity, Localization, and Language Development 214
11 Neuroplasticity: Evidence from Unilateral Brain Lesions in Children 254
12 Continuity and Change in the Development of Children with Autism 274
13 Biological and Behavioral Heterogeneity in Autism: Roles of Pleiotropy and Epigenesis 292
Pt. IV Interventions
14 Issues in Developing Effective Interventions 341
15 Pervasive Developmental Disorders: Listening Training and Language Abilities 365
Pt. V Conclusions
16 Development, Learning, and Neuroplasticity: Where We Are Now 389
Index 399
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