Channelopathies of the Nervous System

Channelopathies of the Nervous System

by Michael R. Rose
     
 

ISBN-10: 0750645075

ISBN-13: 9780750645072

Pub. Date: 05/29/2001

Publisher: Elsevier Health Sciences

* A unique reference focusing on the rapidly developing field of channelopathies of common neurological disorders
• Written specifically for the clinical neurologist and neuroscientist
• It reviews the underlying scientific principles of ion channel function and the current research and its clinical applications

Overview

* A unique reference focusing on the rapidly developing field of channelopathies of common neurological disorders
• Written specifically for the clinical neurologist and neuroscientist
• It reviews the underlying scientific principles of ion channel function and the current research and its clinical applications

Product Details

ISBN-13:
9780750645072
Publisher:
Elsevier Health Sciences
Publication date:
05/29/2001
Pages:
347
Product dimensions:
0.88(w) x 7.00(h) x 10.00(d)

Table of Contents

Part 1: Basic science (physiology, molecular biology and pharmacology): Physiology of ion channels; Molecular biology of ion channels; Pharmacology of ion channels; Part 2 Assessment of channel function (in vitro and in vivo): Techniques for assessing ion channel function; in vitro; Neurophysiological investigation of channelopathies in vivo; Part 3: Channel gene expression, and distribution and its relationship to disease and normal development: Plasticity of ion channel gene expression as a substrate for channelopathies; The role and consequences of ion channel distribution and dysfunction in pain; The role of ion channel distribution, dysfunction and gene expression in demyelinating disease; Part 4: Neuromuscular channel gene disorders (genetic): Chloride and sodium channel myotonias; The periodic paralyses: hyperkalaemic and hypokalaemic paralysis; Malignant hyperthermia; Acetylcholine receptor channelopathies and other congenital myasthenic syndromes; Part 5: Neuromuscular channel disorders (acquired): Myasthenia gravis and the Lambert Eaton syndrome; Autoimmune neuromyotonia; Part 6: Central nervous system channel disorders: Periodic and progressive ataxias; Epilepsies; Paroxysmal movement disorders as channelopathies; Hyperekplexia; Migraine: a multifactorial, neurovascular episodic channelopathy?; Part 7: Toxin-induced channel disorders: Ciguatera (fish poisoning); Part 8: Potential channel disorders: Potential channelopathies: selected myotonic disorders - Schwartz Jampel syndrome (SJS), myotonic dystrophy (DM), myotonic dystrophy type-2 (DM-2), proximal myotonic myopathy (PROMM) and proximal myotonic dystrophy (PDM); Andersen's syndrome; Part 9: Conclusion;

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