Chemical Carcinogenesis

Paperback (Softcover reprint of the original 1st ed. 1982)
$93.15 price
(Save 5%)$99.00 List Price
Other sellers (Paperback)
  • All (3) from $92.63   
  • New (2) from $92.63   
  • Used (1) from $135.09   
Sending request ...

Product Details

  • ISBN-13: 9781468443363
  • Publisher: Springer US
  • Publication date: 11/28/2012
  • Series: Nato Science Series A: (closed)
  • Edition description: Softcover reprint of the original 1st ed. 1982
  • Pages: 492
  • Product dimensions: 7.00 (w) x 10.00 (h) x 1.04 (d)

Table of Contents

Section I: Chemicals as Carcinogens.- Chemical Carcinogenesis by Polycyclic Aromatic Hydrocarbons.- N-Substituted Aromatic Compounds.- Metabolic Epoxidation of Aflatoxin B1 and Its Metabolites: Patterns of DNA Adduct Formation and Removal in Relation to Biological Effects.- The Problematic Use of Chemical Class Controls in Absence of Information on the Underlying Mechanism.- Discussion.- Section II: DNA Adducts.- DNA Lesions: Nature and Genesis.- DNA Alkaline Elution: Physical Basis of the Elution Process and Validation of this Method as a Screeing Procedure to Identify Chemical Carcinogens.- DNA Fragmentation: Its Predictivity as a Short Term Test.- Measurement of Viscous and Elastic Components of Native DNA Fiber Following Carcinogen Administration.- Initiation of Experimental Liver Carcinogenesis by Chemicals: Are the Carcinogen Altered Hepaytes Stimulated to Grow into Foci by Different Selection Procedures Identical?.- Influence of DNA Conformation on DNA Methylation and the Direct Binding of N-Methyl-N-Nitroso-N1-Nitro-Guanidine.- Genotoxic Effects of Drugs: Experimental Findings Concerning Some Chemical Families of Therapeutic Relevance.- Discussion.- Section III: Chemicals as Promotors.- Phenobarbital and Other Liver Tumor Promotors.- Molecular Mechanisms of Multistage Carcinogenesis.- Alterations of Liver Architecture in Mice Treated with Anabolic Androgens and Diethylnitrosamine.- Discussion.- Section IV: Carcinogenesis as Multistep Process.- Some Critical Consideration Concerning the Sequential Analysis of Carcinogenesis with Chemicals.- Benign and Malignant Tumor Induction in Mouse Skin.- Progress in the Study of In Vitro Neoplastic Transformation.- Pulse-Carcinogenesis by Ethylnitrosourea in the Developing Rat Nervous System: Molecular and Cellular Mechanisms.- Chromatin, Nuclei and Water: Alterations and Mechanisms for Chemically-Induced Carcinogenesic.- The Cytoskeleton: An Intermediate in the Expression of the Transformed Phenotype in Malignant Cells.- Discussion.- List of Participants.- Contributor Index.

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Terms of Use.
  • - Barnes & reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)