The Chemistry of the Morita-Baylis-Hillman Reaction

Overview

Carbon-carbon bond formations and functional group transformations are the most fundamental reactions for the construction of molecular frameworks and are at the forefront of organic chemistry research. The Morita-Baylis-Hillman (MBH) type reactions possess the two most important requirements - atom economy and generation of multi-functional groups. The last decade has seen exponential growth of the MBH reaction and its applications. In fact, it is already one of the most powerful carbon-carbon bond-forming ...

See more details below
Other sellers (Hardcover)
  • All (10) from $55.75   
  • New (9) from $55.75   
  • Used (1) from $231.54   
Sending request ...

Overview

Carbon-carbon bond formations and functional group transformations are the most fundamental reactions for the construction of molecular frameworks and are at the forefront of organic chemistry research. The Morita-Baylis-Hillman (MBH) type reactions possess the two most important requirements - atom economy and generation of multi-functional groups. The last decade has seen exponential growth of the MBH reaction and its applications. In fact, it is already one of the most powerful carbon-carbon bond-forming methods widely used in organic synthesis. Since the 1990s, more and more research groups have initiated work on different aspects of the MBH reaction. These have focused on the scope of the substrates, novel catalysts (especially chiral catalysts), reaction mechanisms, and synthetic applications. Consequently, there is now a need for a reference detailing the chemistry of this important reaction. This unique book summarizes the MBH reaction, aza-MBH reaction and asymmetric MBH/aza-MBH reaction including the latest research and mechanistic investigations. It provides a complete overview of MBH-type reactions aimed at synthetic organic chemists of all levels within academia and industry. The chapters cover the; origin and growth of the Morita-Baylis-Hillman reaction; reactant classes and reaction conditions; catalytic mechanisms; achiral and chiral catalytic systems; transformations of functional groups; use of Morita-Baylis-Hillman adducts and derivatives as starting materials to construct compounds with carbocyclic or heterocyclic frameworks, and the applications of the MBH reaction in synthesizing natural products.

Read More Show Less

Product Details

  • ISBN-13: 9781849731294
  • Publisher: Royal Society of Chemistry, The
  • Publication date: 4/28/2011
  • Series: RSC Catalysis Series , #8
  • Pages: 563
  • Sales rank: 1,280,782
  • Product dimensions: 6.40 (w) x 9.30 (h) x 1.50 (d)

Meet the Author

Min Shi has been a professor of organic chemistry in the State Key Laboratory of Organometallic Chemistry at the Shanghai University of Organic Chemistry (SIOC) within the Chinese Academy of Science for the past ten years. Professor Shi's research focuses on the organic synthesis, asymmetric catalysis, organocatalysis, and chemical fixation of CO2. With twenty years experience in the field, Min Shi has published over 300 articles in the most prestigious publications in the field and is also regularly invited to review articles submitted for publication in many academic journals. Feijun Wang obtained a BSc and MSc from the China University of Mining and Technology. After receiving his PhD (on the synthesis of novel ozaloline ligands with a biphenyl backbone and their applications in asymmetric catalysis) from the Shanghai Jiao Tong University School of Chemistry and Technology, he joined the group of Professor Min Shi. His research now focuses on the development of novel rotation restricted ligands and their applications in asymmetric catalysis.

Read More Show Less

Table of Contents

Morita-Baylis-Hillman Reaction; Catalytic System for the Morita-Baylis-Hillman Reaction; Transformations of Functional Groups in Morita-Baylis-Hillman Adducts; Morita-Baylis-Hillman Adducts or Derivatives for the Construction of Cyclic Frameworks; The application of Morita-Baylis-Hillman Reaction for the Synthesis of Natural Products

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)