Chronic Fatigue Syndrome and the Body's Immune Defense System: What Does the Research Say?

Overview

New evidence on the origins and treatment of chronic fatigue syndrome!

Written by one of the leading experts in the field, Chronic Fatigue Syndrome and the Body?s Immune Defense System presents vital new information on a crippling disorder that has the biomedical community searching for answers. Current research suggests CFS is associated with immune abnormalities that can potentially account for its origin and development. With at least one-third of tested CFS patients showing ...

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Overview

New evidence on the origins and treatment of chronic fatigue syndrome!

Written by one of the leading experts in the field, Chronic Fatigue Syndrome and the Body?s Immune Defense System presents vital new information on a crippling disorder that has the biomedical community searching for answers. Current research suggests CFS is associated with immune abnormalities that can potentially account for its origin and development. With at least one-third of tested CFS patients showing evidence of activation of the body?s “immune army,” this book is crucial reading for all patients with CFS and for the healthcare professionals they trust.

Chronic Fatigue Syndrome and the Body?s Immune Defense System presents a thorough examination of the connection between immunology and this debilitating disorder. The book is essential as a primer on the human immune system (explaining fundamental terms and concepts), an overview of immunopathology, and a review of therapeutic interventions that are immune-based. It also explores the links between immune, endocrine, and nervous system abnormalities and the need for a combined research approach to understanding the different manifestations of CFS.

Chronic Fatigue Syndrome and the Body?s Immune Defense System explains:

  • how infectious viruses, bacteria, and fungi could be direct causes of CFS
  • how therapeutic tools like herbal medicine, vaccines, and cell therapy are being used in CFS research
  • how CFS research applies to related conditions, such as fibromyalgia, Gulf War syndrome, sick building syndrome, and multiple chemical sensitivity

    With a consensus diagnostic tool for CFS still lacking, continued, aggressive research is vital to solving the riddle of its origin. Chronic Fatigue Syndrome and the Body?s Immune Defense System represents a significant step forward in the search, giving new hope to patients and new insight to healthcare professionals.

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Editorial Reviews

Doody's Review Service
Reviewer: Marion C. Cohen, PhD (SUNY Downstate Medical Center)
Description: This book brings together a large amount of information about chronic fatigue syndrome (CFS) in a clear, concise manner. Each chapter synthesizes what is known about CFS with respect to a particular subject. Of particular interest is the chapter that covers the available data on CFS in terms of the cross-talk between the immune, endocrine and nervous systems. The data in all the chapters are well referenced.
Purpose: Although the author does not indicate a particular purpose for writing this book, it is clear that it is an attempt to summarize what is currently known about the abnormalities of the immune system in patients suffering from CFS. Anyone who needs this information could find it by doing a search on one of the services. However, the author has put it all together in one slim volume saving much time and effort for others. The book is one of breadth rather than depth but with the references in hand, the depth can easily be obtained.
Audience: This is a book that is written for anyone who is interested in chronic fatigue syndrome. It will be useful for physicians, researchers, and sophisticated patients who need information on the immune system in CFS patients. The author is an expert in this area and conducts research on the immunotherapy of AIDS and CFS. He has also edited a number of books on CFS.
Features: The book brings together many of the findings relating to CFS that have appeared over the past 20-plus years. It is short enough so that it could easily be read cover to cover. However, the book is divided into chapters that focus on specific areas on which CFS has its greatest impact: the relationship between the nervous, immune and endocrine systems; the role of cytokines; how the cells of the immune system function and whether there is an imbalance among certain cell types; the relationship of CFS and autoimmune diseases; and current therapeutic approaches. Thus it would not be necessary to read it all if one were interested in some topic in particular. On the other hand, the text is only 79 pages while the references comprise an additional 32 pages.
Assessment: This is a small book packed full of information about CFS that would be useful to anyone who needs to learn something about the disease. The lengthy list of references provides a starting point for a search for more details. The author is an expert on this disease, which is reflected in the way the book is clearly written with just enough detail to focus on the areas that are important in research on CFS, as well as its treatment.

4 Stars! from Doody
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Product Details

Table of Contents

  • Chapter 1. Overview of the Human Immune System and Its Relevance to Chronic Fatigue Syndrome
  • Chapter 2. Cross-Talk Between the Immune, Endocrine, and Nervous Systems
  • Neuroendocrinology of Chronic Fatigue Syndrome
  • Chapter 3. The Soldiers of the Immune Army: Immune Cell Phenotypic Distributions
  • T Lymphocytes
  • B Lymphocytes
  • Natural Killer Cells
  • Neutrophils
  • Chapter 4. Immune Cell Function
  • T and B Lymphocytes
  • Natural Killer Cells
  • Monocytes
  • Eosinophils
  • Chapter 5. Cytokines and Other Soluble Immune Mediators
  • Cytokines
  • Immunoglobulins
  • Autoantibodies
  • Circulating Immune Complexes
  • Chapter 6. Potential Infectious and Autoimmune Etiologies for Chronic Fatigue Syndrome
  • Infectious Agents As Possible Direct Causes of CFS
  • Autoimmunity and CFS: Infectious Agents As Possible Indirect Causes of CFS
  • Chapter 7. The Th1/Th2 Imbalance Paradigm in Chronic Fatigue Syndrome
  • Chapter 8. Immunotherapy of Chronic Fatigue Syndrome: Th1/Th2 Balance Modulation
  • Lymph Node Cell-Based Immunotherapy
  • Mycobacterium Vaccae
  • Staphylococcal Vaccine
  • Sizofiran
  • Panax Ginseng
  • Juzen-Taiho-To
  • Chapter 9. Concluding Remarks
  • References
  • Index
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