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Doody's Review ServiceReviewer: Angela Johnston, PharmD (University of Illinois at Chicago College of Pharmacy)
Description: This is a compilation of information published in the Clin Alert newsletter over a two-year time period. Information presented in Clin Alert involves newly published data in the following areas: adverse drug reactions; drug interactions; and notifications and health advisories from the food and drug administration (FDA).
Purpose: The purpose is to update healthcare professionals on newly published drug interactions, adverse drug reactions, and notifications and health advisories from the FDA.
Audience: The target audience includes pharmacists and all healthcare professionals involved in patient care.
Features: This book is divided into the following chapters: alternative medicines, antihistamines, anti-infectives, anti-neoplastics, autonomic agents, blood, cardiac, central nervous system, eyes/ears/nose/throat, electrolyte, gastrointestinal, hormones, and miscellaneous. Each report has a title that provides a brief explanation of the case followed by a brief summary of the events and references. The indexes, drug, FDA/Manufacturer alert, first published reports, legal action and drug interaction index, provide multiple mechanisms to locate desired information.
Assessment: This book serves as a review of the previously published Clin Alert newsletter over an undefined, two year time period. Advantages of the reference include provision of useful information, well-referenced material, and the inclusion of herbal medications. Disadvantages include: the time period to which the information covers is not clearly defined; information is limited to only that which was published in Clin Alert newsletters; it is not a comprehensive collection of information on adverse drug reactions and interactions; and the indexes are not user friendly. References such as Stockley's Drug Interactions: A Source Book of Adverse Interactions, Their Mechanisms, Clinical Importance and Management, 5th Edition (APhA, 1999), and Davies' Textbook of Adverse Drug Reactions (Oxford University Press, 1991) provide a more comprehensive listing of adverse drug reactions and drug interactions. Medline is another valuable alternative for the identification of case reports.