Clinical Chemistry: Theory, Analysis and Correlation

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A comprehensive textbook covering the principles of clinical chemistry and the methods and procedures used in clinical chemistry. Over 50 chapters examine introductory principles such as lab management and safety as well as methods used in diagnosing diseases of specific body systems and chemicals.

The book contains black-and-white illustrations.

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Overview

A comprehensive textbook covering the principles of clinical chemistry and the methods and procedures used in clinical chemistry. Over 50 chapters examine introductory principles such as lab management and safety as well as methods used in diagnosing diseases of specific body systems and chemicals.

The book contains black-and-white illustrations.

Read More Show Less

Editorial Reviews

Ronald W. McLawhon
This book represents a revised, up-to-date edition of a text recognized as one of the standards in the fields of clinical chemistry and clinical laboratory science. The authors and multiple contributors take a systematic approach to the principles and theory of laboratory techniques and methods used in the practice of clinical chemistry, and provide a comprehensive overview of disease pathophysiology with clinical correlation of laboratory data. This book retains the same familiar format of two earlier editions, permitting educators to use existing teaching plans. However, several new or extensively revised chapters have been added to ensure that the reader is presented with information reflecting the significant changes that have occurred in recent years in clinical chemistry and the general healthcare practice environment. This book is intended primarily as a teaching text for students in medical technology and clinical laboratory science, but is also appropriate for individuals pursuing advanced training in clinical chemistry. It is a valuable, state-of-the-art reference for practicing clinical chemists and pathologists. The authors and various contributors are well known and respected in their subspecialty areas of expertise. The text is divided into two major sections: laboratory techniques and pathophysiology. Analytical method reviews are now incorporated at the end of chapters, where clinical utility of specific diagnostic tests is discussed. Each chapter features an introductory outline, a set of learning objectives, a glossary of key terms, and an extensive, updated list of references. Summary tables and figures are clear, concise, and contribute significantly to thelearning process. This book continues to be an excellent resource for both beginners and established practitioners to find general information and to review current trends and practices in clinical chemistry. It is well organized, complete, and fills the niche between basic introductory texts and advanced, technically complex reference manuals on the market.
From The Critics
Reviewer:Ronald W. McLawhon, MD, PhD (University of Chicago Pritzker School of Medicine)
Description:This book represents a revised, up-to-date edition of a text recognized as one of the standards in the fields of clinical chemistry and clinical laboratory science. The authors and multiple contributors take a systematic approach to the principles and theory of laboratory techniques and methods used in the practice of clinical chemistry, and provide a comprehensive overview of disease pathophysiology with clinical correlation of laboratory data.
Purpose:This book retains the same familiar format of two earlier editions, permitting educators to use existing teaching plans. However, several new or extensively revised chapters have been added to ensure that the reader is presented with information reflecting the significant changes that have occurred in recent years in clinical chemistry and the general healthcare practice environment.
Audience:This book is intended primarily as a teaching text for students in medical technology and clinical laboratory science, but is also appropriate for individuals pursuing advanced training in clinical chemistry. It is a valuable, state-of-the-art reference for practicing clinical chemists and pathologists. The authors and various contributors are well known and respected in their subspecialty areas of expertise.
Features:The text is divided into two major sections: laboratory techniques and pathophysiology. Analytical method reviews are now incorporated at the end of chapters, where clinical utility of specific diagnostic tests is discussed. Each chapter features an introductoryoutline, a set of learning objectives, a glossary of key terms, and an extensive, updated list of references. Summary tables and figures are clear, concise, and contribute significantly to the learning process.
Assessment:This book continues to be an excellent resource for both beginners and established practitioners to find general information and to review current trends and practices in clinical chemistry. It is well organized, complete, and fills the niche between basic introductory texts and advanced, technically complex reference manuals on the market.
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Product Details

  • ISBN-13: 9780801627057
  • Publisher: Mosby, Incorporated
  • Publication date: 3/1/1984
  • Edition description: 1st ed
  • Pages: 1510

Table of Contents

1 Basic Laboratory Principles and Techniques 3
Pt. I Basic Laboratory Principles and Techniques
Pt. II Calculations in Clinical Chemistry
2 Laboratory Management 45
3 Sources and Control of Preanalytical Variation 65
4 Spectral Techniques 83
5 Chromatography: Theory and Practice 106
6 Liquid Chromatography 128
7 Gas Chromatography 151
8 Mass Spectrometry 167
9 Radioisotopes in Clinical Chemistry 185
10 Electrophoresis 199
11 Immunological Reactions 213
12 Immunochemical Techniques 225
13 Principles for Competitive-Binding Assays 250
14 Measurement of Colligative Properties 270
15 Electrochemistry: Principles and Measurements 277
16 Automation 292
17 Point-of-Care (Near-Patient) Testing 313
18 Laboratory Information Systems 323
19 Laboratory Statistics 342
20 Reference Intervals and Clinical Decision Limits 365
21 Quality Control for the Clinical Chemistry Laboratory 382
22 Evaluation of Methods 402
23 Interferences in Chemical Analysis 424
24 Physiology and Pathophysiology of Body Water and Electrolytes 439
25 Acid-Base Control and Acid-Base Disorders 464
26 Renal Function 484
27 Liver Function 505
28 Bone Disease 528
29 The Pancreas: Function and Chemical Pathology 555
30 Gastrointestinal Function and Digestive Disease 571
31 Cardiac and Muscle Disease 593
32 Diabetes Mellitus 613
33 Coronary Artery Disease and Disorders of Lipid Metabolism 642
34 Alcoholism 682
35 Iron, Porphyrin, and Bilirubin Metabolism 696
36 Hemoglobin 716
37 Human Nutrition 736
38 Trace Elements 746
39 Vitamins 760
40 Pregnancy and Fetal Development 793
41 Extravascular Biological Fluids 820
42 Nervous System 828
43 General Endocrinology 849
44 Thyroid 867
45 The Gonads 892
46 Adrenal Hormones and Hypertension 912
47 Diseases of Genetic Origin 939
48 Molecular Biology in the Clinical Laboratory 969
49 Neoplasia 983
50 Laboratory Evaluation of the Transplant Recipient and Donor 1004
51 Toxicology 1017
52 Addiction and Substance Abuse 1034
53 Classifications and Descriptions of Proteins, Lipids, and Carbohydrates 1041
Pt. I Proteins
Pt. II Lipids
Pt. III Carbohydrates
54 Clinical Enzymology 1056
55 Isoenzymes and Isoforms 1077
56 Therapeutic Drug Monitoring (TDM) 1086
Pt. I Basic overview of principles
Pt. II Practical aspects of TDM
57 Examination of Urine 1114
App. A: Buffer Solutions 1140
App. B: Preparation of Buffer Solutions 1142
App. C: Concentrations of Common Acids and Bases 1145
App. D: Gases in Common Laboratory Use-Technical Information 1146
App. E: Major Plasma Proteins 1148
App. F: Conversions Between Conventional and SI Units 1149
App. G: Conversions Between Conventional and SI Units for Specific Analytes 1150
App. H: Body Surface of Children 1152
App. I: Body Surface of Adults 1153
Index 1155
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