Clinical Mr Neuroimaging: Diffusion, Perfusion and Spectroscopy

Clinical Mr Neuroimaging: Diffusion, Perfusion and Spectroscopy

by Jonathan H. Gillard, Adam D. Waldman, Peter B. Barker
     
 
The physiological magnetic resonance techniques of diffusion imaging, perfusion imaging and spectroscopy offer insights into brain structure, function and metabolism. Until recently, they were mainly applied within the realm of medical research, but with their increasing availability on clinical MRI machines, they are now coming into clinical practice for the

Overview

The physiological magnetic resonance techniques of diffusion imaging, perfusion imaging and spectroscopy offer insights into brain structure, function and metabolism. Until recently, they were mainly applied within the realm of medical research, but with their increasing availability on clinical MRI machines, they are now coming into clinical practice for the evaluation of neuropathology in individual patients. This book provides the reader with a thorough review of the underlying physical principles of each of these methods, as well as comprehensive coverage of their clinical applications. Topics covered include single- and multiple-voxel MRS techniques, MR perfusion based on both arterial spin labelling and dynamic bolus tracking approaches, and diffusion-weighted imaging, including techniques for mapping brain white matter fiber bundles. Clinical applications are reviewed in depth for each technique, with case reports included throughout the book. Attention is also drawn to possible artifacts and pitfalls associated with these techniques.

Editorial Reviews

From the Publisher
"This book is indeed a welcomed addition to the rapidly growing knowledge base of clinical neuroimaging, as it will undoubtedly provide medical professionals with a clear and informative reference to emerging state-of-the-art neuroimaging applications. Clinical MR Neuroimaging: Diffusion, Perfusion and Spectroscopy by J. Gillard et al. is a wonderful reference book for physicians and radiologists looking for comprehensive coverage of clinical applications, as well as for biomedical engineers, MR physicists, and other more interested in the underlying physical principles of these novel MR techniques." Health Physics, Dardo Tomasi

"This is a long overdue text that clarifies and simplifies the application of contemporary MR diffusion imaging (especially diffusion tensor imaging and white matter tractography), MR perfusion imaging and MR spectroscopy. Its greatest value is its comprehensive treatment of the theory of these imaging methods without resorting to advanced mathematical descriptions that would be beyond the level of many practicing physicians. I have not seen a comparable text on the market."--Doody's Review Service®

"The physiologic and functional MR techniques described in this book are here to stay and already used in the field, beyond academic sites. The editors achieve their goal of providing detailed reference tutorials for neuroimagers to understand current uses. This book is worth the cost as a reference for those who do neuroimaging or refer patients for neuroimaging studies." - Radiology, Allan J. Fox, MD

Doody's Review Service
Reviewer: Robert James Bert, M.D., Ph.D.(University of Colorado Health Sciences Center)
Description: This book presents basic physic principals, basic mathematical principals and contemporary clinical applications of diffusion and perfusion MR imaging and MR spectroscopy. Its illustrations are well chosen to instruct the reader not only in the principals of these techniques, but also in their clinical applications.
Purpose: The author's foreword states that the purpose of this book is to create a reference for perfusion MRI, diffusion MRI and MR spectroscopy such that these techniques can be widely applied for routine use in clinical practice. Such a book is long overdue in our profession. In my opinion, this book accomplishes this goal.
Audience: While it was not explicitly stated, I believe it was the intent of the authors that this book was designed, primarily, for the practicing neuroradiologist. In my judgment, this would be the correct audience for this book. It would also be an appropriate text for neuroradiology fellows, especially in their second year. There are multiple true authors, often more than one for a given chapter. The authors are well chosen for most, if not all, chapters.
Features: This book provides an introduction to the mathematics, physics and clinical applications of current commercially-available diffusion MRI, perfusion MRI and MR spectroscopy packages. The book illustrates the application of these techniques in aiding diagnosis of a broad range of pathologic processes. An excellent feature of this book is the appropriate number and quality of illustrating examples. The color figures liven readablity. The number of presented spectrographs illustrating pathology is superior to most other currently available texts.One drawback of this text is the number of typographical and grammatical errors. Careful editing appears to have been sacrificed. These errors are distracting and unnecessarily degrade the quality of the reading experience.
Assessment: This is a long overdue text that clarifies and simplifies the application of contemporary MR diffusion imaging (especially diffusion tensor imaging and white matter tractography), MR perfusion imaging and MR spectroscopy. Its greatest value is its comprehensive treatment of the theory of these imaging methods without resorting to advanced mathematical descriptions that would be beyond the level of many practicing physicians. I have not seen a comparable text on the market. However, the editing of the text is suboptimal with respect to spelling, typographical accuracy and grammar.

Product Details

ISBN-13:
9780521824576
Publisher:
Cambridge University Press
Publication date:
12/28/2004
Pages:
852
Product dimensions:
8.62(w) x 10.87(h) x 1.81(d)

Meet the Author

Jonathan Gillard's research interests have centred on MR angiographic techniques. He is an author of over 50 peer reviewed publications and a journal reviewer for many publications.

Adam Waldman's main research interests are in clinical psychological imaging of neurodegenerative diseases and brain tumours. He has published widely and contributed to several textbooks.

Peter Barker has focussed his research career on the development of magnetic resonance spectroscopy techniques for the study of human brain metabolism and diagnosis of neurological disease. He is an author of over 100 peer reviewed publications, and a frequent journal reviewer.

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