Clinical Pharmacokinetics: Concepts and Applications / Edition 3

Clinical Pharmacokinetics: Concepts and Applications / Edition 3

by Malcolm Rowland, Thomas Tozer, Tozer
     
 

ISBN-10: 0683074040

ISBN-13: 9780683074048

Pub. Date: 10/28/1995

Publisher: Lippincott Williams & Wilkins

Since pharmacokinetics can greatly affect how different patients respond to the same drug, both students and physicians need a basic clinical understanding of this vital area. The Third Edition of Clinical Pharmacokinetics provides a practical perspective, with these added features considerations of both stereochemistry and the increasing number of

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Overview

Since pharmacokinetics can greatly affect how different patients respond to the same drug, both students and physicians need a basic clinical understanding of this vital area. The Third Edition of Clinical Pharmacokinetics provides a practical perspective, with these added features considerations of both stereochemistry and the increasing number of polypeptide and protein drugs being developed; the range and number of problems at the end of each chapter has been expanded; a second color added to make the text more user friendly; important equations highlighted by shading.

Compatibility:
BlackBerry® OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile™ Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC

Product Details

ISBN-13:
9780683074048
Publisher:
Lippincott Williams & Wilkins
Publication date:
10/28/1995
Edition description:
Third Edition
Pages:
608
Product dimensions:
8.58(w) x 8.80(h) x 1.04(d)

Table of Contents

Definitions of Symbols
1Why Clinical Pharmacokinetics?1
2Basic Considerations11
3Intravenous Dose18
4Extravascular Dose34
5Therapeutic Response and Toxicity53
6Constant-Rate Regimens66
7Multiple-Dose Regimens83
8Movement Through Membranes109
9Absorption119
10Distribution137
11Elimination156
12Integration With Kinetics184
13Variability203
14Genetics220
15Age and Weight230
16Disease248
17Interacting Drugs267
18Concentration Monitoring290
19Distribution Kinetics313
20Pharmacologic Response340
21Metabolite Kinetics367
22Dose and Time Dependencies394
23Turnover Concepts424
24Dialysis443
Selected Reading463
Appendix I. Additional Concepts and Derivations469
Appendix II. Answers to Problems507
Index586

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