Clinical Pharmacology and Therapeutics Lecture Notes


Clinical Pharmacology and Therapeutics Lecture Notes provides a clear and accessible overview of all the key prescribing topics needed for medical finals and beyond. Detailed coverage and discussion of pharmacology in a clinical context, combined with an easy-to-understand, readable style, helps improve and test understanding of pharmacological principles and reasoning on rotation and into the foundation ...

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Clinical Pharmacology and Therapeutics Lecture Notes provides a clear and accessible overview of all the key prescribing topics needed for medical finals and beyond. Detailed coverage and discussion of pharmacology in a clinical context, combined with an easy-to-understand, readable style, helps improve and test understanding of pharmacological principles and reasoning on rotation and into the foundation years.

Key features for this edition include:
• Clinical scenarios to root each chapter firmly in a real-life setting
• Prescribing points flagging up important issues of clinical relevance
• Expanded sections on drugs you may need in a hurry, prescribing and its pitfalls, and paediatric prescribing
• A self-assessment section to test your knowledge and help prepare for examinations

Clinical Pharmacology and Therapeutics Lecture Notes is an ideal resource for all medical students, junior doctors, and other prescribers, whether learning how pharmacological principles relate to clinical situations, brushing up on the basics while on rotation, or looking for a comprehensive overview of prescribing and therapeutics.

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Editorial Reviews

From The Critics
Reviewer: Thomas L. Pazdernik, PhD (University of Kansas Medical Center)
Description: This book evolved 30 years ago from a series of lecture notes by three young educators at the University of Glasgow, who compiled and edited these notes into an excellent learning resource for young doctors in training. This edition is the first that doesn't have any of the original editors, but it carries on the tradition of providing a concise bridge from the basic sciences to the art of prescribing therapeutic drugs for doctors in training.
Purpose: The goal is to provide a brief, clearly written, and up to-to-date review of clinical pharmacology. The editors have done an outstanding job of achieving this goal.
Audience: Medical students, junior doctors, and other prescribers are the intended audience.
Features: The three parts of the book cover principles, aspects of therapeutics in the treatment of disease, and the practical aspects of prescribing therapeutic agents. The chapters are well organized and written and each includes high yield boxes containing relevant clinical scenarios, prescribing points, and key points. Summary tables and well-constructed, simple figures emphasizing key mechanisms are appropriately used. Doctors in training will definitely cherish the last part that deals with the practical aspects of prescribing drugs and includes topics such as individual dosing, role of hepatic and renal disease in prescribing medications, special considerations for the young and elderly, drugs used during pregnancy and breastfeeding, pharmacoeconomics, overdoses, emergency drugs, and prescribing pitfalls. At the end there is a self-assessment exam followed by answers to the questions. The book is not meant to be comprehensive, but provides a concise summary of concepts and information that doctors must master to safely prescribe drugs.
Assessment: This is an excellent resource for doctors in training who must master the principles of clinical pharmacology in order to prescribe therapeutic agents safely in the diagnosis, prevention, and treatment of diseases.
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Product Details

  • ISBN-13: 9781118344811
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 5/6/2013
  • Series: Lecture Notes Series
  • Edition description: New Edition
  • Edition number: 9
  • Pages: 328
  • Sales rank: 1,447,723
  • Product dimensions: 9.10 (w) x 6.60 (h) x 0.70 (d)

Meet the Author

Gerard A. McKay is Consultant Physician and Honorary Clinical Associate Professor, Glasgow Royal Infirmary and University of Glasgow

Matthew R. Walters is Professor of Clinical Pharmacology and Director, Clinical Pharmacology and Therapeutics, Institute of Cardiovascular and Medical Sciences, University of Glasgow

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Table of Contents

Contributors, vi

Preface, vii

Foreword, ix

Part 1 Principles of clinical pharmacology

1 Pharmacodynamics and pharmacokinetics, 3

2 Clinical trials and drug development, 11

Part 2 Aspects of therapeutics

3 Drugs and gastrointestinal disease, 19

4 Management of coronary artery disease and its complications, 29

5 Primary and secondary prevention of cardiovascular disease, 52

6 Drugs used to treat respiratory disease, 71

7 Drugs used to treat neurological disease, 81

8 Treatment of psychiatric disorders, 97

9 Antimicrobial therapy, 111

10 HIV and antiretroviral treatment, 132

11 Travel medicine and tropical disease, 143

12 Drugs and endocrine disease, 153

13 Drugs and the reproductive system, 169

14 Drugs and the urological system, 178

15 Cancer therapeutics, 185

16 Drugs and infl ammatory joint disease, 197

17 Immunopharmacology, 204

18 Drugs and the blood including anticoagulants and thrombolytic drugs, 215

19 Drugs used for pain relief and anaesthesia, 228

Part 3 Practical aspects of prescribing

20 Clinical pharmacokinetics: dosage individualisation, 241

21 Influence of renal and hepatic disease on pharmacokinetics and pharmacodynamics, 247

22 Prescribing for the young and the elderly, 252

23 Drugs in pregnant and breastfeeding women, 255

24 Pharmacoeconomics: the economic evaluation of new drugs, 262

25 Poisoning and drug overdose, 269

26 Drugs you may need in a hurry, 283

27 Prescribing and its pitfalls, 287

Self assessment questions, 294

Self assessment answers, 299

Index, 302

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