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From The CriticsReviewer:Thomas L. Pazdernik, PhD(University of Kansas Medical Center)
Description:This is a well designed and written tenth edition of a popular British clinical pharmacology textbook.
Purpose:The authors state that they have attempted to "make pharmacology understandable for those whose primary interest lie elsewhere but who recognize that they need some knowledge of pharmacology if they are to meet their moral and legal 'duty of care' to their patients." The authors have done an admirable job of making pharmacology understandable to practitioners.
Audience:The book is written for the teachers, students, and practitioners who are concerned with evidence-based drug therapy.
Features:It is divided into the principles of pharmacology (chapters 1-10) and the application of these principles to the practice of medicine in subsequent specialist chapters. Each chapter starts with a text box synopsis of the chapter followed by bulleted points to be covered and ends with a guide to further reading. A PIN number provides access an electronic version of the book at Elsevier's Student Consult web site. The book focuses on current evidence-base medicine and refers to the many consensus or best practice guidelines that are now available. Section 1 covers general information on drugs including drug discovery and clinical evaluations, whereas section 2 deals with general principles of pharmacology including pharmacokinetics, pharmacodynamics, toxicology, and dug abuse. These general discussions are followed by six specialist sections divided according to a systems approach to the study of pharmacology, covering infection and immunity,nervous system, cardiorespiratory and renal systems, blood and neoplastic disease, gastrointestinal system, and endocrine system and metabolic conditions. The book does an excellent job of focusing on important principles and provides sufficient detail on important drugs for readers to understand the evidence for prescribing drugs, with referral to best practice sites and formularies for many of the specific details on individual drugs. American readers need to recognize the different drugs and different spellings in the British compared to American formularies.
Assessment:I highly recommend that this much needed, updated edition of this clinical pharmacology textbook be added to the evidence-based resource library of every individual prescribing drugs. However, it is more appropriate for European than American prescribers.