Clinical Radiation Oncology: Expert Consult - Online and Print / Edition 3

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First Prize winner, Oncology Book Category, British Medical Association 2012 Medical Book Competition

• Deepen your knowledge with a comprehensive, clinical approach to the scientific foundations of radiation oncology and general oncology as well as state-of-the-art techniques and modalities.
• Implement a multidisciplinary, "team care" approach to providing intricate treatment plans for patients, often in conjunction with medical oncologists, and surgeons.
• Broaden your understanding of the basic biology of the disease processes.
• Examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches.
• Quickly and easily find critical information thanks to an easily accessible, full-color design with over 800 color figures that clearly depict treatment techniques.

• Get broad multimodality perspectives and unique insights from a diverse team of respected editors and contributors -many of whom are new to this edition - affiliated with institutions across North America and internationally
• Access the fully searchable text anywhere, anytime at, along with references, additional images and tables, video clips and more!
• Stay current with comprehensive updates throughout that include a new chapter on survivorship issues, and additional video clips on treatments such as prostate and penile cancer brachytherapy.
• Improve outcomes by providing the most effective treatment for each patient with expanded coverage of new modalities and treatment regimens.
• Understand and comply with the latest staging guidelines.

Drs. Gunderson and Tepper give you quick access to all the clinical tools you need to master the newest techniques and modalities in radiation oncology.

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Editorial Reviews

Doody's Review Service
Reviewer: James G Douglas, MD, MS (Memorial Hospital of Sweetwater County)
Description: The previous editions of this comprehensive textbook of radiation oncology have been considered among the definitive resources for practicing and in-training radiation oncologists. It focuses on the scientific principles and specifics of treatment modalities and techniques, as well as disease sites commonly treated by radiation oncologists. Each section in this third edition has been enhanced and expanded with new topics and new chapters.
Purpose: This edition fulfills its goal of serving as a comprehensive textbook of radiation oncology.
Audience: The book targets the radiation community as a whole. It is appropriate not only for students and residents in the specialty, but also for academic and community radiation oncologists. Leaders in the field spearhead each chapter, presenting pertinent, evidence-based guidance on each topic as well as expert opinion on controversial issues. The authors, experts in the field, have assembled an excellent cadre of associate editors and writers.
Features: Although wide-ranging in its topics, this book remains focused, concise, and unambiguous. It is broken down into three main sections: scientific foundations of the specialty including radiobiology and physics; techniques and modalities; and disease sites. Chapters in each section incorporate full-color graphs, figures, diagrams, and pictures that skillfully illustrate key concepts. Each chapter has a clear outline for easy reference. It not only addresses the most up-to-date, evidence-based techniques and modalities, but also points out the future direction the field is taking, important in this rapidly evolving specialty.
Assessment: This updated third edition is one of the definitive books in the field of radiation oncology and should be a part of all radiation oncologists' reference libraries. It incorporates the pertinent scientific principles, technical aspects of treatment planning, and details of the diseases germane to the field of radiation oncology.
From the Publisher
"The previous editions of this comprehensive textbook of radiation oncology have been considered among the definitive resources for practicing and in-training radiation oncologists…This updated third edition should be a part of all radiation oncologists' reference libraries. It incorporates the pertinent scientific principles, technical aspects of treatment planning, and details of the diseases germane to the field of radiation oncology."

- James G. Douglas, MD, MS, Indiana University School of Medicine

5 Star- Doody's Rating, March 2013

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Product Details

  • ISBN-13: 9781437716375
  • Publisher: Elsevier Health Sciences
  • Publication date: 11/10/2011
  • Edition description: New Edition
  • Edition number: 3
  • Pages: 1660
  • Product dimensions: 8.90 (w) x 11.10 (h) x 2.50 (d)

Table of Contents


Chapter 1. Biological Basis of Radiation Oncology
Chapter 2. Molecular and Cellular Biology
Chapter 3. Dose Response Modifiers in Radiation Oncology
Chapter 4. Interaction of Chemotherapy and Radiation
Chapter 5. Biologics and Interactions with Radiation

Chapter 6. Radiation Oncology Physics

Chapter 7. Surgical Principles
Chapter 8. Principles of Chemotherapy
Chapter 9. Imaging in Oncology
Chapter 10. Nuclear Medicine
Chapter 11. Health Services Research in Radiation Oncology: Toward Achieving the Achievable for Patients with Cancer
Chapter 12. Statistics and Clinical Trials


Chapter 13. Brachytherapy
Chapter 14. Conformal Therapy: Treatment Planning, Treatment Delivery, and Clinical Results
Chapter 15. Intraoperative Irradiation
Chapter 16. Stereotactic Irradiation: Linear Accelerator and Gamma Knife
Chapter 17. Total Body Irradiation
Chapter 18. Charged Particle Radiotherapy
Chapter 19. Neutron Radiotherapy
Chapter 20. Hyperthermia
Chapter 21. Targeted Radionuclide Therapy
Chapter 22. Palliation of Metastases: Bone, Spinal Cord, Brain, Liver


Chapter 23. Low-Grade Gliomas
Chapter 24. High-Grade Gliomas
Chapter 25. Meningioma, Ependymoma and Other Adult Brain Tumors
Chapter 26. Pituitary Tumors
Chapter 27. Spinal Tumors
Chapter 28. Orbital, Ocular, and Optic Nerve Tumors

Chapter 29. Oral Cavity
Chapter 30. Oropharyngeal Cancer
Chapter 31. Nasopharyngeal Carcinoma
Chapter 32. Larynx and Hypopharnyx Cancer
Chapter 33. Sinonasal Cancer
Chapter 34. Salivary Gland Cancer
Chapter 35. Thyroid Cancer
Chapter 36. Squamous Cell Carcinoma Metastatic to the Neck from an Unknown Head and Neck Primary Site
Chapter 37. Management of the Neck
Chapter 38. Cutaneous Carcinoma
Chapter 39. Melanoma

Chapter 40. Small Cell Lung Cancer
Chapter 41. Non-Small-Cell Lung Cancer
Chapter 42. Cancer of the Esophagus
Chapter 43. Uncommon Thoracic Malignancies

Chapter 44. Stomach Cancer
Chapter 45. Pancreatic Cancer
Chapter 46. Hepatobiliary Tumors
Chapter 47. Colon Cancer
Chapter 48. Rectal Cancer
Chapter 49. Anal Carcinoma

Chapter 50. Prostate Cancer
Chapter 51. Bladder Cancer
Chapter 52. Testicular Cancer
Chapter 53. Kidney and Ureteral Carcinoma
Chapter 54. Penile Cancer

Chapter 55. Cervical Cancer
Chapter 56. Endometrial Cancer
Chapter 57. Vulvar and Vaginal Carcinoma
Chapter 58. Ovarian Cancer

Chapter 59. Noninvasive Breast Cancer
Chapter 60. Breast Cancer: Stages I and II
Chapter 61. Breast Cancer: Stages T3 and T4 Locally Advanced and Inflammatory Breast Cancer and Postmastectomy Radiation Therapy

Chapter 62. Soft Tissue Sarcoma
Chapter 63. Radiotherapy of Non-malignant Diseases

Chapter 64. Central Nervous System Tumors in Childhood
Chapter 65. Pediatric Soft Tissue Sarcomas
Chapter 66. Pediatric Sarcomas of Bone
Chapter 67. Wilm’s Tumor
Chapter 68. Retinoblastoma
Chapter 69. Neuroblastoma
Chapter 70. Leukemias and Lymphomas in Children
Chapter 71. Hodgkins
Chapter 72. Rare Tumors in Children

Chapter 73. Hodgkin’s Disease
Chapter 74. Non-Hodgkin’s Disease
Chapter 75. Multiple Myeloma and other Plasma Cell Neoplasms
Chapter 76. Mycosis Fungoides


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  • Posted March 1, 2012

    use of multimodal deformable solid registration needed!

    There is a new world intellectual champion in the field of deformable solid registration. Our paper (1) solves an intractable computing problem when the minimum energy does not correspond to the solution. When 100 parallel computers are linked, it will only get to the wrong solutions 100x faster - truly a fastlane to failure (sorry NSF I borrowed your idea and post my challenge on your walls). I am inviting Northern Europe to challenge my intellectual global dominance, solving an intractable computing problem, no future by-passes (1). An active global dominance is like your neighborhood pizza guy stick his recipe on the pizza guy down the street and screaming I am better than you and going to tell all my customers that. Can you imaging what the other pizza guy will do?

    This is the daily email sent out counting the days for a month:
    Time = Day 30 of 30 (Feb 23, 2012), for an active global challenge to be #1.
    Hi, how are you?
    Do you have a faster or know of a more accurate program to solve the problem of large deformations in registering multi-modal images. This is until now an intractable computational problem. Our solution is being integrated into prostate cancer radiation treatment to spare potency. Our solution will benefit the fields of medicine, computing and engineering, so I'm opening this challenge to the colleagues in computer science, applied mathematics and engineering.

    My claim = # 1 in solving large deformations in image registration.

    I am gathering the answers to this global challenge from more than a few dozen universities in Asia, Europe, North and South Americas, Australia, Middle East, and the Nordic region. I'll start to write it up for publication in the end of Feb, 2012.
    I welcome anyone to meet this challenge. This rigorous established the singularity of our algorithm (1). It is anticipated that our work will survive this world-wide challenge.

    To demonstrate the big gap between what is commercially available and what is needed in the clinic. Using reference 2 as an example, the MRI information was transferred to the CT scan using fusion. Fair to say, the study was performed using the state of the art fusion algorithms available. Rightly so, the IGRT was done with or with image registration. However, without image registration or simply use fusion (that implies rigid body translations and rotations) are simply subpar and should be wiped out. Your algorithm is by-passable, more computers in parallel will likely bring you down. Please challenge my assertion here. I love to be wrong on this. Anyhow, yours (3) is by-passable, right? Since we have solved deformable solid registration (1) with error estimation. The accuracy of the fusion is judged by eye-balling only. There is no quantification of the additional planning margin required to account for the errors in registration. Our algorithms have extensions in the arena of engineering and applied mathematics. Our implemented algorithms are a part of our Interactive Specialized Prostate Image Registration Ensemble (InSPIRE) available at request, and it is ready for clinical implementation, although it is patent pending. I am wiping clean the treatment planning and multimodal deformable registration. It would get 5 star assuming I were wrong. Publisher, Drs. Cox and Ang, and ASTRO, please do correct me, I would love to hear I were wrong !
    Rex Cheung, MD, Ph.D. P&S
    Associate Professor of Radiology,
    Texas A and M.
    Bryn Mawr, Philadelphia, PA.
    Ref: S

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