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Doody's Review ServiceReviewer: Elisa Ann Hofmann, BS, MD (Fox Valley Endocrinology)
Description: This volume presents information based on clinical research regarding the pathophysiology of insulin-resistant states, primarily type 2 diabetes and obesity.
Purpose: The purpose is to provide a comprehensive overview of the regulation of carbohydrate, protein, and lipid metabolism in patients with type 2 diabetes and nondiabetic obese persons, based on clinical investigation. The book has met the objectives, and it is needed because there are few such compilations of the advances in clinical research devoted to the pathophysiology of insulin-resistant states.
Audience: This volume was primarily written for endocrinologists specializing in diabetes. It will also be beneficial to general internists/practitioners, medical students, and researchers in the field of diabetes. The contributors are highly credible, consisting of endocrinologists, nutritionists, and physiologists from major universities and medica1 centers in seven countries, including the U.S., Denmark, Germany, and Canada.
Features: The book contains a sufficient number of tables and figures to illustrate the contributors' points, but perhaps an overabundance of references. The references are relevant and current, with most dated 1980-1996. Each chapter begins with an introduction and ends with a summary of the research and current theories presented in the chapter.
Assessment: Because the contributors are among the leading clinical researchers in the field of insulin resistance, this volume is high in quality. It will be very useful in understanding the current theories regarding the mechanisms leading to various insulin-resistant states. This book should be obtained by medical bookstores and libraries and by persons interested in this field.