Clinical Research in Diabetes and Obesity, Volume 2: Diabetes and Obesity / Edition 1

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Overview

An unprecedented compilation of state-of-the-art advances in clinical research by premier clinical scientists around the world. This volume discusses the methods of clinical research and the interpretation of their results in studies of normal individuals, obese subjects, and patients with diabetes mellitus. Along the way, the authoritative contributors writing here illuminate how changes in the hormone action and substrate metabolism of healthy humans may lead to obesity and noninsulin-dependent diabetes mellitus.

The book contains black-and-white illustrations.

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Editorial Reviews

Elisa A. Hofmann
This volume presents information based on clinical research regarding the pathophysiology of insulin-resistant states, primarily type 2 diabetes and obesity. The purpose is to provide a comprehensive overview of the regulation of carbohydrate, protein, and lipid metabolism in patients with type 2 diabetes and nondiabetic obese persons, based on clinical investigation. The book has met the objectives, and it is needed because there are few such compilations of the advances in clinical research devoted to the pathophysiology of insulin-resistant states. This volume was primarily written for endocrinologists specializing in diabetes. It will also be beneficial to general internists/practitioners, medical students, and researchers in the field of diabetes. The contributors are highly credible, consisting of endocrinologists, nutritionists, and physiologists from major universities and medica1 centers in seven countries, including the U.S., Denmark, Germany, and Canada. The book contains a sufficient number of tables and figures to illustrate the contributors' points, but perhaps an overabundance of references. The references are relevant and current, with most dated 1980-1996. Each chapter begins with an introduction and ends with a summary of the research and current theories presented in the chapter. Because the contributors are among the leading clinical researchers in the field of insulin resistance, this volume is high in quality. It will be very useful in understanding the current theories regarding the mechanisms leading to various insulin-resistant states. This book should be obtained by medical bookstores and libraries and by persons interested in this field.
Doody's Review Service
Reviewer: Elisa Ann Hofmann, BS, MD (Fox Valley Endocrinology)
Description: This volume presents information based on clinical research regarding the pathophysiology of insulin-resistant states, primarily type 2 diabetes and obesity.
Purpose: The purpose is to provide a comprehensive overview of the regulation of carbohydrate, protein, and lipid metabolism in patients with type 2 diabetes and nondiabetic obese persons, based on clinical investigation. The book has met the objectives, and it is needed because there are few such compilations of the advances in clinical research devoted to the pathophysiology of insulin-resistant states.
Audience: This volume was primarily written for endocrinologists specializing in diabetes. It will also be beneficial to general internists/practitioners, medical students, and researchers in the field of diabetes. The contributors are highly credible, consisting of endocrinologists, nutritionists, and physiologists from major universities and medica1 centers in seven countries, including the U.S., Denmark, Germany, and Canada.
Features: The book contains a sufficient number of tables and figures to illustrate the contributors' points, but perhaps an overabundance of references. The references are relevant and current, with most dated 1980-1996. Each chapter begins with an introduction and ends with a summary of the research and current theories presented in the chapter.
Assessment: Because the contributors are among the leading clinical researchers in the field of insulin resistance, this volume is high in quality. It will be very useful in understanding the current theories regarding the mechanisms leading to various insulin-resistant states. This book should be obtained by medical bookstores and libraries and by persons interested in this field.

4 Stars! from Doody
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Product Details

  • ISBN-13: 9781617370519
  • Publisher: Springer-Verlag New York, LLC
  • Publication date: 11/9/2010
  • Series: Contemporary Biomedicine Series , #15
  • Edition description: Softcover reprint of hardcover 1st ed. 1997
  • Edition number: 1
  • Pages: 392
  • Product dimensions: 10.00 (w) x 7.00 (h) x 0.83 (d)

Table of Contents

Part I: Obesity. Energy Metabolism and Obesity, James O. Hill. Metabolic Parameters and Energy Expenditure Before and After Weight Loss, John M. Amatruda. Regulation of Food Intake and Body Weight, Michael W. Schwartz, Denis G. Baskin, Karl J. Kaiyala, Steven C. Woods, and Daniel Porte, Jr. Mechanisms of Insulin Resistance in Obesity, David E. Kelley and Jean-Aime Simoneau. Effects of Obesity on Lipid Metabolism, Ahmed H. Kissebah and Glenn R. Krakower. Part II: Noninsulin-Dependent Diabetes Mellitus. Genetics of Noninsulin-Dependent Diabetes Mellitus (NIDDM), Henning Beck-Nielsen, Allan Vaag, and Kirsten Ohm Kyvik. Insulin Secretion in Type II Diabetes Mellitus, Yogish C. Kudva and Peter C. Butler. Insulin Action and Insulin Resistance in Noninsulin-Dependent Diabetes Mellitus, John J. Nolan and Jerrold M. Olefsky. Dyslipidemia in Noninsulin-Dependent Diabetes Mellitus, Lisa A. Kosmiski and Robert H. Eckel. Exercise and Noninsulin-Dependent Diabetes Mellitus (NIDDM), Judith G. Regensteiner, Suzanne L. Brandenberg, and Jane E. B. Reusch. Glucose Toxicity and Insulin Resistance in NIDDM, Hannele Yki-Järvinen. Energy Metabolism and Sympathetic Activity in Patients with Insulin Resistance, Luc Tappy and Nicolas Paquot. Effects of NIDDM on Vascular Tone Regulation, Alain D. Baron and Helmut O. Steinberg. Part III: Insights Gained from Other Insulin-Resistance Syndromes. Insulin Resistance in the Polycystic Ovary Syndrome, Andrea Dunaif and Carol Beth Book. Dietary Management of NIDDM, Frank Q. Nuttall and Mary C. Gannon. Hypertension and Insulin Resistance, Andrea Natali, Stefano Taddei, and Ele Ferrannini. Lessons Learned from Clinical and Basic Research Applied to the Study of Patients with Severe Insulin Resistance, David E. Moller and Heike Benecke. Treatment of Obesity Through Changes in Lifestyle, Rena R. Wing. Syndrome X: Past, Present, and Future, Gerald M. Reaven. Index.

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