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From the Publisher"The book is well written and R code is clearly commented in most cases. The chapters provide very useful material for practical clinical trial data analyses. … The results of the analyses are illustrated with excellent graphical presentations. Bootstrap and simulations are utilized extensively."
—International Statistical Review, 2013
"The book fills its purpose well, successfully covering the majority of the major trial design and analysis techniques. … a good primer to the most commonly used methods and their utilisation in R, as well as extensive lists of references to more detailed considerations. … this book can certainly stand on any biostatisticians’shelf as a useful text. For the seasoned methodologist, it provides a helpful introduction to the R environment. For R proponents, it delivers a simple overview of the established clinical biostatistics methodology."
—Michael Grayling, ISCB News, December 2013
"… the book is very well written and includes up-to-date, comprehensive, and carefully selected topics for the analysis of clinical trials and their step-by-step implementation in R."
—Mizanur Khondoker, Statistical Methods in Medical Research, 22(6), 2013
"The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods. Overall, this book achieves the goal successfully and does a nice job covering most, if not all, major aspects of clinical trial statistics. For those who are well versed in R, this book can serve as a good reference to the established clinical biostatistics methodology; for veteran biostatisticians, this book provides a gentle introduction to the use of R in clinical trial analysis. … a great introductory book for clinical biostatistics with an emphasis on R implementations. I would highly recommend it …The example-based approach is easy to follow and makes the book a very helpful desktop reference for many biostatistics methods."
—Journal of Statistical Software, Vol. 43, July 2011