Clinician's Guide to Cocaine Addiction: Theory, Research, and Treatment

Overview

A product of many years' work by researchers at the renowned Yale Substance Abuse Research Center, this volume constitutes a comprehensive resource on cocaine. Unusually coherent for an edited book, the volume's chapters reflect the contributors' long collaboration in making significant contributions to the field. The Clinician's Guide covers the history of cocaine research, the pharmacology and phenomenology of the drug, and current treatment ...
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Overview

A product of many years' work by researchers at the renowned Yale Substance Abuse Research Center, this volume constitutes a comprehensive resource on cocaine. Unusually coherent for an edited book, the volume's chapters reflect the contributors' long collaboration in making significant contributions to the field. The Clinician's Guide covers the history of cocaine research, the pharmacology and phenomenology of the drug, and current treatment approaches for cocaine abuse.

Part I reviews the history of cocaine research with a discussion of America's first cocaine epidemic and the evolution of understanding about the properties of the drug. Part II, on pharmacology and phenomenology, presents the scientific basis of clinical practice, illuminating the linkage between research and practice. Many chapters in this preclinical section feature figures and diagrams that illustrate important principles of neurotransmitter and drug action relevant to the psychology of abuse and treatment. Included are such topics as basic and clinical neurobiology, conditioning and cognitive factors, the role of the clinical laboratory, and reports from family/genetic studies.

Covering treatment approaches, Part III features chapters on epidemiology, medical complications and emergency management, pharmacotherapy, psychotherapy, and inpatient treatment. Specific approaches for special populations are discussed in chapters on comorbid psychopathology, cocaine abuse in methadone programs, and the pregnant cocaine abuser. Throughout, case examples and clinical extracts clearly illustrate key points in the management of these patients. In many examples, the preclinical basis of a clinical intervention is illustrated to help the reader develop his or her own ideas for innovative treatment approaches. A final chapter recaps the treatment approaches and provides a framework for matching clients to the appropriate treatment modality.

A complete compendium on research and treatment, the Clinician's Guide To Cocaine Addiction is a necessary resource for all mental health professionals who work with substance abusers. Providing an excellent introduction to and overview of the field, it will be valued by counselors and health care providers new to the area and by students in advanced undergraduate and graduate-level courses on drug abuse and its treatment.
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Editorial Reviews

From the Publisher

Everything you ever wanted to know about cocaine is contained in this comprehensive, highly readable book. It should be of benefit to scholars and researchers, as well as practicing clinicians.' --Charles R. Schuster, Ph.D., National Institute on Drug Abuse

This is a very good book. It makes a real contribution to the practical literature on cocaine. I found it highly informative...it is written at a level that nonspecialists in the area will also find both entertaining and useful.'
--Charles P. O'Brien, Ph.D., Addiction Treatment Research Center, University of Pennsylvania

"I had forgotten how many outstanding researchers in cocaine either are presently or were recently at the Yale Substance Abuse Center...In addition, I had forgotten the breadth of research on cocaine at Yale; from neurochemistry to history to epidemiology to medication development to psychotherapy to genetics to comorbidity. Finally, I had forgotten how many important findings were first described at Yale...Given this wealth of talent, this edited text is much better than other single-university texts...Most chapters provide a well-referenced and fair summary of prior work, plus a presentation of clinical examples and existing programs at Yale...Offers a good description of the more important areas in cocaine research." --John R. Hughes, M.D., The American Journal on Addictions

Booknews
Twenty contributions from the faculty of the Yale Substance Abuse Research Center coherently integrate preclinical and clinical areas in their coverage of the history of cocaine research, pharmacology & phenomenology, and treatment. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

  • ISBN-13: 9780898621921
  • Publisher: Guilford Publications, Inc.
  • Publication date: 7/3/1992
  • Series: The Guilford Substance Abuse Series Series
  • Edition number: 1
  • Pages: 405
  • Product dimensions: 6.34 (w) x 9.40 (h) x 1.23 (d)

Meet the Author


Thomas R. Kosten, M.D., is Associate Professor of Psychiatry and Director of the Substance Abuse Research Center at Yale University School of Medicine. A Research Scientist Awardee of the National Institute on Drug Abuse since 1987, he is a member of the Committee for Added Qualifications in Addiction Psychiatry on the American Board of Psychiatry and Neurology, and the board of directors of the Committee on the Problems of Drug Dependence. He is a founding member of the American Academy of Psychiatrists in Alcoholism and Addiction, where he has been chairman for scientific programs and research and currently serves as a member at large. In 1990, the Committee on the Problems of Drug Dependence awarded him the Cochin Award for his contributions to the development of medications to treat substance abuse. He is an editorial board member on a number of professional journals and has published over 200 papers, books, and reviews.
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Table of Contents

Pt. I History of Cocaine Research
1 America's First Cocaine Epidemic: What Did We Learn? 3
2 Cocaine Research at Yale 16
3 Evolving Conceptualizations of Cocaine Dependence 33
Pt. II Pharmacology and Phenomenology
4 Basic Neurobiology of Cocaine: Actions within the Mesolimbic Dopamine System 55
5 Animal Models for Cocaine Abuse 84
6 Cue-Reactivity and Cocaine Addiction 109
7 Cognitive Factors Associated with Cocaine Abuse and Its Treatment: An Analysis of Expectancies of Use 128
8 Clinical Neurobiology of Cocaine Administration and Abstinence 151
9 "Craving For and Fear of Cocaine": A Phenomenologic Update on Cocaine Craving and Paranoia 172
10 The Role of Drug Analysis in Cocaine Abuse Treatment and Research 193
11 Family/Genetic Studies of Cocaine Abusers and Opioid Addicts 206
Pt. III Treatment
12 Cocaine Epidemiology 225
13 Medical Complications of Cocaine Use 241
14 Pharmacotherapies 273
15 Psychotherapy for Cocaine Abuse: Approaches, Evidence, and Conceptual Models 290
16 Inpatient Treatment of Cocaine Addiction 314
17 Comorbid Psychopathology and Cocaine Addiction 335
18 Cocaine Abuse within Methadone Maintenance Programs 359
19 Pregnancy and Women's Issues 374
20 Matching Patients to Treatment 389
Index 396
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