Clinicians' Guide to Lipids and Coronary Heart Disease

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ilinicians' Guide to Lipids and Coronary Heart Diseaser provides a clear, comprehensive and up-to-date account of the role of lipid management in the prevention of coronary heart disease. The science underlying lipid metabolism is put into context for the practising physician, including recent developments in inflammation, plaque biology and the transition to serious events. Risk factor modification, including lifestyle change and cholesterol lowering by diet and medication are discussed fully. Landmark clinical ...

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2003 Paperback Brand New Book, Paperback, no spine or cover creases, clean, tight, unmarked, 2nd Edition Text is a comprehensive guide to the relationship of lipids to coronary ... heart disease and to assist in patient management. Discusses the science underlying lipid metabolism and the mechanisms of drug action. Also addresses screening, assessment, and intervention. For clinicians. All orders are shipped by kbooks every business day. Read more Show Less

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Overview

ilinicians' Guide to Lipids and Coronary Heart Diseaser provides a clear, comprehensive and up-to-date account of the role of lipid management in the prevention of coronary heart disease. The science underlying lipid metabolism is put into context for the practising physician, including recent developments in inflammation, plaque biology and the transition to serious events. Risk factor modification, including lifestyle change and cholesterol lowering by diet and medication are discussed fully. Landmark clinical trials, and the messages that can be drawn from them, are highlighted throughout. The practical focus is maintained through the consideration of specific patient groups demonstrating particular clinical importance, management difficulties or areas of current controversy.
Key Features of the Second Edition: *Enhanced world-wide applicability through broader coverage of global risk assessment and international management guidelines

• Sound evidence base
*Increased and omproved use of boxes to highlight key points and sections of special interest

• Plentiful color illustrations

British orientation; incl. lipid-lowering trials, non-lipid risk factor modification, diet, drugs, women, elderly etc.

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Editorial Reviews

Doody's Review Service
Reviewer: John F. Moran, MD (Loyola University Stritch School of Medicine)
Description: This is a book about coronary risk factors with an almost exclusive emphasis on lipids and lipoprotein management. The book is divided into sections, the first on lipoprotein metabolism and epidemiology, the second concerns diagnosis, the third covers intervention, and the fourth is special areas such as the economic aspects of lipid management.
Purpose: The purpose is to help physicians in patient management and especially the relationship of lipids to coronary heart disease. The authors see an insight into lipid management as important as the interpretation of electrocardiograms, x-rays, and blood counts.
Audience: The authors have directed this book at practitioners; but cardiology fellows, medical residents, and endocrinologists would find much interesting material here.
Features: The first chapter is an excellent review of lipoprotein metabolism with all due emphasis on cholesterol and LDL cholesterol metabolism. They review the Seven Countries Study as well as MRFIT and the British Heart Study. Although lipids are emphasized here, there is an attempt to relate these to other coronary risk factors. Rare and very rare hyperlipidemias are covered, such as Tangier's Disease and Fish Eye Disease. The authors are from the United Kingdom and make some interesting comments about the economics of risk factors. The sale of cigarettes to children younger than 16 years old generates a tax revenue of £108 million pounds ($170.6 million) and a total tax revenue of £8,463 million ($13.37 billion). Other risk factors are reviewed: exercise, obesity, homocysteine fibrinogen. and other inflammatory markers such as C reactive protein. The Framingham Coronary Risk Factor is compared to the British Regional Heart Study. They would treat all patients with a greater than 30 percent, 10-year CHD risk. Blood pressure reduction is emphasized. The book is up-to-date with reference to the recent Heart Protection Study. There is a detailed section on cholesterol lowering medications and a good review on lipid lowering trials with special emphasis on the cholesterol controversy of the 1990s. There are many pertinent tables that are color coded for emphasis. There are six pages of abbreviations to help conserve text space, which include abbreviations for clinical trials as well as some that are not so commonly used, such as COC (combined oral contraceptive) and HAART (high active and retroviral therapy).
Assessment: Although the book has a definite British slant, there is good information here. The book finishes up with 20 cases, all with accompanying smiling patient pictures and comments by the authors. One interesting comment is Dr. Morrell's finding that hypothyroidism in patients given statins seems more likely to generate muscular aches and pains. One positive aspect about this is that the authors use milligrams percent for measurements in addition to millimoles per liter. There are tables contrasting the National Cholesterol Education Program and Adult Treatment Panel III Guidelines with the European Atherosclerosis Guidelines. Overall, this is a welcome addition to the medical literature.

3 Stars from Doody
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Product Details

  • ISBN-13: 9780340764084
  • Publisher: Taylor & Francis
  • Publication date: 5/1/2003
  • Series: Clinicians Guide Series, #2
  • Edition description: REV
  • Edition number: 2
  • Pages: 384
  • Product dimensions: 9.70 (w) x 7.40 (h) x 0.80 (d)

Meet the Author

University College, London

Beaconsfield Road Surgery, Hastings, East Sussex

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Table of Contents

Part One: Background

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