Coenzyme Q: Molecular Mechanisms in Health and Disease

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Since its discovery in 1957, Coenzyme Q has piqued the interest of sci entists from a wide range of disciplines because of its bioenergetics, vitamin-like behavior, and interactions with antioxidant vitamins E a nd C. Coenzyme Q: Molecular Mechanisms in Health and Disease is a comp rehensive treatise on this often-studied coenzyme. International exper ts cover the research that led to its emergence as an exciting, new di etary supplement.

The book contains black-and-white illustrations.

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Editorial Reviews

Summarizes developments in various areas of Coenzyme Q (CoQ) research and describes research that led to its emergence as a new dietary supplement. An interdisciplinary approach covers everything from biochemical mechanisms to health benefits. Discusses new concepts relating to extramitochondrial functions of CoQ, analyzes recent discoveries in biosynthetic pathways for CoQ, and explores the role of CoQ as an antioxidant. Some specific topics include CoQ for alcoholic liver disease, implication of CoQ depletion in heart transplantation, and genetic analysis of CoQ biosynthesis. Kagan teaches environmental and occupational health and pharmacology at the University of Pittsburgh; Quinn teaches biochemistry at King's College, London. Annotation c. Book News, Inc., Portland, OR (
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Product Details

  • ISBN-13: 9780849387326
  • Publisher: Taylor & Francis
  • Publication date: 8/30/2000
  • Series: Modern Nutrition Series
  • Edition description: New Edition
  • Pages: 408
  • Product dimensions: 7.30 (w) x 10.30 (h) x 1.11 (d)

Table of Contents

Chemical and Biophysical Properties
Biochemical Mechanisms in Electron transport in Mitochondria and Extramitochondrial Locations
Antioxidant Mechanisms
Prooxidant Mechanisms
Biosynthesis and Nutritional Sources
Dietary Supplementation and Plasma/Tissue Concentrations
HEALTH EFFECT OF COENZYME Q. Coenzyme Q Status and Oxidative Stress in Vivo
Cardiovascular Pathology
Liver Injury
Physical Performance/Training

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