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Cognition and Cancer
     

Cognition and Cancer

by Christina A. Meyers, James R. Perry
 

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ISBN-10: 0521854822

ISBN-13: 9780521854825

Pub. Date: 12/31/2008

Publisher: Cambridge University Press

Most people afflicted by cancer will experience cognitive impairment, sometimes referred to as 'chemobrain' or' chemofog', due to the various direct and indirect effects of their disease and its treatment. In addition, patients with primary or metastatic tumors of the brain experience direct neurologic symptoms due, for example, to the location of their disease,

Overview

Most people afflicted by cancer will experience cognitive impairment, sometimes referred to as 'chemobrain' or' chemofog', due to the various direct and indirect effects of their disease and its treatment. In addition, patients with primary or metastatic tumors of the brain experience direct neurologic symptoms due, for example, to the location of their disease, surgical intervention, and the late effects of treatment such as radiotherapy. The aim of this book is to serve as a resource for health care professionals working with cancer patients who experience cognitive changes as a result of their cancer and its treatment. It provides practical information to help improve care by reviewing and describing brain-behavior relationships; research-based evidence on cognitive changes that occur with various cancers and cancer treatments; assessment techniques, including neurocognitive assessment and neuroimaging techniques; the future of neurocognitive research in the area, including animal models and clinical trials; and intervention strategies for affected patients. In short, it will explain how to identify, assess, and treat these conditions.

This book is essential reading for anyone involved in the clinical care of cancer patients with neurocognitive problems, or who undertake research in this area.

Product Details

ISBN-13:
9780521854825
Publisher:
Cambridge University Press
Publication date:
12/31/2008
Pages:
353
Product dimensions:
7.30(w) x 9.80(h) x 0.90(d)

Table of Contents

List of contributors vii

Preface xi

Section 1 Cognition and the brain: measurement, tools, and interpretation

1 Introduction Christina A. Meyers James R. Perry 3

2 Clinical neuropsychology Jill B. Rich Angela K. Troyer 6

3 Brain imaging investigation of chemotherapy-induced neurocognitive changes Brenna C. McDonald Andrew J. Saykin Tim A. Ahles 19

4 Role of Neuropsychological assessment in cancer patients Elana Farace 33

5 Neuropsychological assessment of adults with cancer Anne E. Kayl Robert Collins Jeffrey S. Wefel 44

6 Neuropsychological assessment of children with cancer Louise Penkman Fennell Robert W. Butler 56

Section 2 Effects of cancer and cancer treatment on cognition

7 Biological bases of radiation injury to the brain Edward G. Shaw Mike E. Robbins 83

8 Cognitive dysfunction related to chemotherapy and biological response modifiers Jeffrey S. Wefel Robert Collins Anne E. Kayl 97

9 Effect of hormones and hormonal treatment on cognition Christien Schilder Sanne Schagen Frits van Dam 115

10 Low-grade Gliomas Martin J. B. Taphoorn Charles G. Niëet;l 142

11 High-grade Gliomas Michael J. Glantz John W. Conlee 156

12 Brain metastases Deepak Khuntia Beela S. Mathew Christina A. Meyers Sterling Johnson Minesh P. Mehta 170

13 Primary central nervous system lymphoma Denise D. Correa 187

14 Childhood brain tumors H. Stacy Nicholson Louise Penkman Fennell Robert W. Butler 198

15 Neurofibromatosis Bartlett D. Moore, Ill John M. Slopis 211

16 Hematological malignancies Melissa Friedman Mercedes Fernandez 228

17 Paraneoplastic disorders Edward Dropcho 239

18 Symptomatic therapies and supportive care issues Alan Valentine Eduardo Bruera258

19 Animal models and cancer-related symptoms Adrian Dunn 270

Section 3 Interventions and implications for clinical trials

20 Behavioral strategies and rehabilitation Dona E. C. Locke Jane H. Cerhan James F. Malec 281

21 Support services Bebe Guill Renee H. Raynor 295

22 Pharmacological Interventions for the treatment of radiation-induced brain injury Edward G. Shaw Jerome Butler L. Douglas Case Ralph d'Agostino, Jr. John Gleason, Jr. Edward Ip Mike E. Robbins Paul Saconn Stephen R. Rapp 312

23 Neurocognitive testing in clinical trials Jennifer A. Smith Jeffrey S. Wefel 320

Index 329

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