Methods, Processes, and Tools for Collaboration

"The time has come to fundamentally rethink how we handle the building of knowledge in biomedical sciences today. This book describes how the computational sciences have transformed into being a key knowledge broker, able to integrate and operate across divergent data types."—Bryn Williams-Jones, Associate Research Fellow, Pfizer

The pharmaceutical industry utilizes an extended network of partner organizations in order to discover ...

See more details below
Collaborative Computational Technologies for Biomedical Research

Available on NOOK devices and apps  
  • NOOK Devices
  • Samsung Galaxy Tab 4 NOOK 7.0
  • Samsung Galaxy Tab 4 NOOK 10.1
  • NOOK HD Tablet
  • NOOK HD+ Tablet
  • NOOK eReaders
  • NOOK Color
  • NOOK Tablet
  • Tablet/Phone
  • NOOK for Windows 8 Tablet
  • NOOK for iOS
  • NOOK for Android
  • NOOK Kids for iPad
  • PC/Mac
  • NOOK for Windows 8
  • NOOK for PC
  • NOOK for Mac
  • NOOK for Web

Want a NOOK? Explore Now

NOOK Book (eBook)
BN.com price
(Save 42%)$151.00 List Price
Note: This NOOK Book can be purchased in bulk. Please email us for more information.


Methods, Processes, and Tools for Collaboration

"The time has come to fundamentally rethink how we handle the building of knowledge in biomedical sciences today. This book describes how the computational sciences have transformed into being a key knowledge broker, able to integrate and operate across divergent data types."—Bryn Williams-Jones, Associate Research Fellow, Pfizer

The pharmaceutical industry utilizes an extended network of partner organizations in order to discover and develop new drugs, however there is currently little guidance for managing information and resources across collaborations.

Featuring contributions from the leading experts in a range of industries, Collaborative Computational Technologies for Biomedical Research provides information that will help organizations make critical decisions about managing partnerships, including:

  • Serving as a user manual for collaborations

  • Tackling real problems from both human collaborative and data and informatics perspectives

  • Providing case histories of biomedical collaborations and technology-specific chapters that balance technological depth with accessibility for the non-specialist reader

A must-read for anyone working in the pharmaceuticals industry or academia, this book marks a major step towards widespread collaboration facilitated by computational technologies.

Read More Show Less

Editorial Reviews

From the Publisher
"The book is of interest to researchers developing IT systems in the pharmaceutical industry, and for those participating in drug discovery collaborations." (Book News, 1 October 2011)

"What unveiled itself as I turned the pages was ... a truthful, meaningful accounting of an evolving social science, perhaps a hope that the pure thrill of crowdsourcing may accelerate the process of discovery while preserving a free market economy.... The book contains... [contributions from a] multi-national task force if you will of some of the world's finest minds in life and physical science and ‘cloud-native' knowledge-sharing." (Untangled Health, 11 August 2011)

Read More Show Less

Product Details

Meet the Author

SEAN EKINS, MSc, PhD, DSc, is the Principal at Collaborations in Chemistry, and Collaborations Director at Collaborative Drug Discovery, Inc., as well as an Adjunct Associate Professor in the Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy. He has published more than 170 papers and book chapters on computational and in vitro drug discovery approaches and has previously edited or co-edited three books for Wiley.

MAGGIE A. Z. HUPCEY, PhD, is a chemist working within the Life Sciences and Healthcare Practice of PA Consulting Group in Princeton, New Jersey. She has worked on collaborative projects for the design and development of new products and processes in the medical device, drug delivery, and drug discovery fields, including presubmission and post-launch regulatory compliance activities.

ANTONY J. WILLIAMS, PhD, FRSC, is currently Vice President, Strategic Development, at the Royal Society of Chemistry and holds an adjunct position at UNC-Chapel Hill. He has written chapters for many books and published more than 100 peer-reviewed papers and book chapters on NMR, predictive ADME methods, Internet-based tools, crowdsourcing, and database curation. He is an active blogger and participant in the Internet chemistry network.

Read More Show Less

Table of Contents

Alpheus Bingham




1. The Need for Collaborative Technologies in Drug Discovery 3
Chris L. Waller, Ramesh V. Durvasula, and Nick Lynch

2. Collaborative Innovation: The Essential Foundation of Scientific Discovery 19
Robert Porter Lynch

3. Models for Collaborations and Computational Biology 39
Shawnmarie Mayrand-Chung, Gabriela Cohen-Freue, and Zsuzsanna Hollander

4. Precompetitive Collaborations in the Pharmaceutical Industry 55
Jackie Hunter

5. Collaborations in Chemistry 85
Sean Ekins, Antony J. Williams, and Christina K. Pikas

6. Consistent Patterns in Large-Scale Collaboration 99
Robin W. Spencer

7. Collaborations Between Chemists and Biologists 113
Victor J. Hruby

8. Ethics of Collaboration 121
Richard J. McGowan, Matthew K. McGowan, and Garrett J. McGowan

9. Intellectual Property Aspects of Collaboration 133
John Wilbanks


10. Scientific Networking and Collaborations 149
Edward D. Zanders

11. Cancer Commons: Biomedicine in the Internet Age 161
Jeff Shrager, Jay M. Tenenbaum, and Michael Travers

12. Collaborative Development of Large-Scale Biomedical Ontologies 179
Tania Tudorache and Mark A. Musen

13. Standards for Collaborative Computational Technologies for Biomedical Research 201
Sean Ekins, Antony J. Williams, and Maggie A. Z. Hupcey

14. Collaborative Systems Biology: Open Source, Open Data, and Cloud Computing 209
Brian Pratt

15. Eight Years Using Grids for Life Sciences 221
Vincent Breton, Lydia Maigne, David Sarramia, and David Hill

16. Enabling Precompetitive Translational Research: A Case Study 241
Sándor Szalma

17. Collaboration in Cancer Research Community: Cancer Biomedical Informatics Grid (caBIG) 261
George A. Komatsoulis

18. Leveraging Information Technology for Collaboration in Clinical Trials 281
O. K. Baek


19. Evolution of Electronic Laboratory Notebooks 303
Keith T. Taylor

20. Collaborative Tools to Accelerate Neglected Disease Research: Open Source Drug Discovery Model 321
Anshu Bhardwaj, Vinod Scaria, Zakir Thomas, Santhosh Adayikkoth, Open Source Drug Discovery (OSDD) Consortium, and Samir K. Brahmachari

21. Pioneering Use of the Cloud for Development of Collaborative Drug Discovery (CDD) Database 335
Sean Ekins, Moses M. Hohman, and Barry A. Bunin

22. Chemspider: a Platform for Crowdsourced Collaboration to Curate Data Derived From Public Compound Databases 363
Antony J. Williams

23. Collaborative-Based Bioinformatics Applications 387
Brian D. Halligan

24. Collaborative Cheminformatics Applications 399
Rajarshi Guha, Ola Spjuth, and Egon Willighagen


25. Collaboration Using Open Notebook Science in Academia 425
Jean-Claude Bradley, Andrew S. I. D. Lang, Steve Koch, and Cameron Neylon

26. Collaboration and the Semantic Web 453
Christine Chichester and Barend Mons

27. Collaborative Visual Analytics Environment for Imaging Genetics 467
Zhiyu He, Kevin Ponto, and Falko Kuester

28. Current and Future Challenges for Collaborative Computational Technologies for the Life Sciences 491
Antony J. Williams, Renée J. G. Arnold, Cameron Neylon, Robin W. Spencer, Stephan Schürer, and Sean Ekins


Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star


4 Star


3 Star


2 Star


1 Star


Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation


  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)