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Doody's Review ServiceReviewer: David J. Dries, MD (University of Minnesota Medical School)
Description: This monograph describes recent research initiatives guiding strategies for management of injury.
Purpose: Presented is a concise description for clinical or basic science investigators studying organ dysfunction following trauma, toxic, or infectious assaults.
Audience: Clinical and research fellows along with teachers in the realm of injury are an appropriate audience for this work. The authors are from across the United States, with many from the Uniform Services University of the Health Sciences in Bethesda, Maryland.
Features: The book's 15 chapters are divided into two sections. Initial discussions center on basic mechanisms including apoptosis, microcirculatory changes, heat stress, immune dysfunction with injury, and infection considerations. Later chapters discuss concepts with more immediate application to the clinician. Emphasis is given to thermal injury, resuscitation, and pulmonary dysfunction. Chapters are written in a clear style with subheadings dividing the material. An appropriate reference list is provided with citations representing original work dating to within two years of publication. There are a few tables and line drawings and no photographs. The table of contents includes chapter organization and authorship while a subject index of 14 pages concludes.
Assessment: This is an excellent summary of research issues pursued by investigators with significant ties to the United States military. This is not a comprehensive review or a clinical textbook. I am sometimes confused at what is a current concept as opposed to a basic mechanism. For example, infections are discussed under basic mechanisms when the content is closer in immediate clinical relevance to the chapters on clinical application. Nonetheless, the subject presentations are excellent for the teacher and student in this arena.