BN.com Gift Guide

Computational Biology from a Statistical Mechanics Perspective

Hardcover (Print)
Buy New
Buy New from BN.com
$86.58
Used and New from Other Sellers
Used and New from Other Sellers
from $108.97
Usually ships in 1-2 business days
Other sellers (Hardcover)
  • All (2) from $108.97   
  • New (1) from $108.97   
  • Used (1) from $127.41   

Overview

Quantitative methods have a particular knack for improving any field they touch. For biology, computational techniques have led to enormous strides in our understanding of biological systems, but there is still vast territory to cover. Statistical physics especially holds great potential for elucidating the structural-functional relationships in biomolecules, as well as their static and dynamic properties.

Breaking New Ground
Computational Biology: A Statistical Mechanics Perspective is the first book dedicated to the interface between statistical physics and bioinformatics. Introducing both equilibrium and nonequilibrium statistical mechanics in a manner tailored to computational biologists, the author applies these methods to understand and model the properties of various biomolecules and biological networks at the systems level.

Unique Vision, Novel Approach
Blossey combines his enthusiasm for uniting the fields of physics and computational biology with his considerable experience, knowledge, and gift for teaching. He uses numerous examples and tasks to illustrate and test understanding of the concepts, and he supplies a detailed keyword list for easy navigation and comprehension. His approach takes full advantage of the latest tools in statistical physics and computer science to build a strong set of tools for confronting new challenges in computational biology.

Making the concepts crystal clear without sacrificing mathematical rigor, Computational Biology: A Statistical Mechanics Perspective is the perfect tool to broaden your skills in computational biology.

Read More Show Less

Product Details

Table of Contents

STATISTICAL MECHANICS
Equilibrium Statistical Mechanics
Z: The Partition Function
Relation to Thermodynamics
Computing Z
Nonequilibrium Statistical Mechanics
Stochastic Processes
The Master Equation
Fluctuation Theorems
The Fokker-Planck and Langevin Equations
Sequence Alignment: A Nonequilibrium Phase Transition
BIOMOLECULES
Molecules, Code and Representation
DNA and RNA: The Building Blocks
Representing RNA Structure
Proteins
DNA
Thermal Stability of DNA: The Melting Transition
The Melting Profiles of Genomic DNA and cDNA
Hybridizing DNA
RNA
Computing RNA Secondary Structure: Combinatorics
The RNA Partition Function
RNA Phase Behavior and Folding Kinetics
Proteins
Proteins: Folding
Proteins: Docking
Electrostatics
Chromatin
Bacterial Chemotaxis: Cooperativity Once More
NETWORKS
Network Dynamics I: Deterministic
Deterministic Dynamics: ?-Repressor Expression
The Turing Insight
The Min System
Network Dynamics II: Fluctuations
Noise in Signaling
Stochastic Cascades
Stochastic Focusing
Fluctuating Gene Network Dynamics
Extrinsic vs. Intrinsic Noise
Networks: Structure
Networks as Graphs
Probability Generating Functions and Network Characteristics
Statistical Mechanics of Networks
Network Growth
INDEX

Read More Show Less

Customer Reviews

Be the first to write a review
( 0 )
Rating Distribution

5 Star

(0)

4 Star

(0)

3 Star

(0)

2 Star

(0)

1 Star

(0)

Your Rating:

Your Name: Create a Pen Name or

Barnes & Noble.com Review Rules

Our reader reviews allow you to share your comments on titles you liked, or didn't, with others. By submitting an online review, you are representing to Barnes & Noble.com that all information contained in your review is original and accurate in all respects, and that the submission of such content by you and the posting of such content by Barnes & Noble.com does not and will not violate the rights of any third party. Please follow the rules below to help ensure that your review can be posted.

Reviews by Our Customers Under the Age of 13

We highly value and respect everyone's opinion concerning the titles we offer. However, we cannot allow persons under the age of 13 to have accounts at BN.com or to post customer reviews. Please see our Terms of Use for more details.

What to exclude from your review:

Please do not write about reviews, commentary, or information posted on the product page. If you see any errors in the information on the product page, please send us an email.

Reviews should not contain any of the following:

  • - HTML tags, profanity, obscenities, vulgarities, or comments that defame anyone
  • - Time-sensitive information such as tour dates, signings, lectures, etc.
  • - Single-word reviews. Other people will read your review to discover why you liked or didn't like the title. Be descriptive.
  • - Comments focusing on the author or that may ruin the ending for others
  • - Phone numbers, addresses, URLs
  • - Pricing and availability information or alternative ordering information
  • - Advertisements or commercial solicitation

Reminder:

  • - By submitting a review, you grant to Barnes & Noble.com and its sublicensees the royalty-free, perpetual, irrevocable right and license to use the review in accordance with the Barnes & Noble.com Terms of Use.
  • - Barnes & Noble.com reserves the right not to post any review -- particularly those that do not follow the terms and conditions of these Rules. Barnes & Noble.com also reserves the right to remove any review at any time without notice.
  • - See Terms of Use for other conditions and disclaimers.
Search for Products You'd Like to Recommend

Recommend other products that relate to your review. Just search for them below and share!

Create a Pen Name

Your Pen Name is your unique identity on BN.com. It will appear on the reviews you write and other website activities. Your Pen Name cannot be edited, changed or deleted once submitted.

 
Your Pen Name can be any combination of alphanumeric characters (plus - and _), and must be at least two characters long.

Continue Anonymously

    If you find inappropriate content, please report it to Barnes & Noble
    Why is this product inappropriate?
    Comments (optional)