Computational Methods for Protein Structure Prediction and Modeling: Volume 2: Structure Prediction / Edition 1

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Overview

Volume 2 of this two-volume sequence focuses on protein Structure prediction and includes protein threading, de novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem. A series of appendices review the biological and chemical basics related to protein structure, computer science for structural informatics, and prerequisite mathematics and statistics. Computational Methods for Protein Structure Prediction and Modeling, Volume 2, provides an essential reference and practical companion for a broad audience ranging from experts in bioinformatics to "consumers" of this information in proteomic research. Written without extensive demands on prior knowledge, this volume is also suitable for use in graduate or advanced.
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Product Details

Meet the Author

Dr. Ying Xu is Regents-GRA Eminent Scholar and Professor at the University of Georgia. Dr. Dong Xu is the Director of the Digital Biology Laboratory at the University of Missouri-Columbia. Dr. Jie Liang is the Director for the Center for Bioinformatics at the University of Illinois at Chicago.

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Table of Contents


Contributors     xvii
Protein Structure Prediction by Protein Threading   Ying Xu   Zhijie Liu   Liming Cai   Dong Xu     1
De Novo Protein Structure Prediction   Ling-Hong Hung   Shing-Chung Ngan   Ram Samudrala     43
Structure Prediction of Membrane Proteins   Xiche Hu     65
Structure Prediction of Protein Complexes   Brian Pierce   Zhiping Weng     109
Structure-Based Drug Design   Kunbin Qu   Natasja Brooijmans     135
Protein Structure Prediction as a Systems Problem   Dong Xu   Ying Xu     177
Resources and Infrastructure for Structural Bioinformatics   Dong Xu   Jie Liang   Ying Xu     207
Biological and Chemical Basics Related to Protein Structures   Hong Guo   Haobo Guo     229
Computer Science for Structural Informatics   Guohui Lin   Dong Xu   Ying Xu     241
Physical and Chemical Basis for Structural Bioinformatics   Hui Lu   Ognjen Perisic   Dong Xu     267
Mathematics and Statistics for Studying Protein Structures   Yang Dai   Ie Liang     299
Index     317
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