Concepts in Biochemistry / Edition 2

Concepts in Biochemistry / Edition 2

by Rodney F. Boyer
     
 

ISBN-10: 0534380069

ISBN-13: 9780534380069

Pub. Date: 04/28/2002

Publisher: Wiley, John & Sons, Incorporated

Rodney Boyer's text gives students a modern view of biochemistry. He utilizes a contemporary approach organized around the theme of nucleic acids as central molecules of biochemistry, with other biomolecules and biological processes treated as direct or indirect products of the nucleic acids.
The topical coverage usually provided in current biochemistry courses…  See more details below

Overview

Rodney Boyer's text gives students a modern view of biochemistry. He utilizes a contemporary approach organized around the theme of nucleic acids as central molecules of biochemistry, with other biomolecules and biological processes treated as direct or indirect products of the nucleic acids.
The topical coverage usually provided in current biochemistry courses is all present - only the sense of focus and balance of coverage has been modified. The result is a text of exceptional relevance for students in allied-health fields, agricultural studies, and related disciplines.

Product Details

ISBN-13:
9780534380069
Publisher:
Wiley, John & Sons, Incorporated
Publication date:
04/28/2002
Edition description:
Older Edition
Pages:
652

Table of Contents

Part IMolecules and Life1
Chapter 1Biochemistry: Setting the Stage3
1.1The Roots of Modern Biochemistry5
1.2Living Matter Contains C, H, O, N, P, and S9
1.3Biological Macromolecules11
1.4Organelles, Cells, and Organisms13
Chapter 2The Flow of Biological Information: Cell Communication29
2.1Storage of Biological Information in DNA31
2.2Transfer of Biological Information to RNA34
2.3Protein Synthesis36
2.4Errors in DNA Processing39
2.5Information Flow Through Cell membranes40
2.6Diseases of Cellular Communication and Drug Design43
Chapter 3Biomolecules in Water47
3.1Water, the Biological Solvent49
3.2Hydrogen Bonding and Solubility52
3.3Cellular Reactions of Water55
3.4Buffer Systems61
Chapter 4Amino Acids, Peptides, and Proteins69
4.1The Amino Acids in Proteins70
4.2Polypeptides and Proteins78
4.3Protein Function79
4.4Protein Size, Composition, and Properties82
4.5Four Levels of Protein Structure84
4.6Protein Primary Structure84
Part IIDynamic Function of Biomolecules95
Chapter 5Protein Architecture and Biological Function97
5.1General Principles of Protein Design98
5.2Elements of Secondary Structure102
5.3Protein Tertiary Structure107
5.4Protein Quaternary Structure110
5.5Protein Structure and Biological Function111
Chapter 6Enzymes I: Reactions, Kinetics, and Inhibition125
6.1Enzymes As Biological Catalysts126
6.2The Kinetic Properties of Enzymes130
6.3Substrate Binding and Enzyme Action136
6.4Enzyme Inhibition141
Chapter 7Enzymes II: Coenzymes, Regulation, Abzymes, and Ribozymes155
7.1Enzyme: Coenzyme Partners156
7.2Allosteric Enzymes161
7.3Cellular Regulation of Enzymes167
7.4Site-Directed Mutagenesis and Abzymes170
7.5Ribozymes172
Chapter 8Carbohydrates: Structure and Biological Function179
8.1Monosaccharides180
8.2Carbohydrates in Cyclic Structures182
8.3Reactions of Monosaccharides186
8.4Polysaccharides192
8.5Glycoproteins198
Chapter 9Lipids, Biological Membranes, and Cellular Transport207
9.1Fatty Acids209
9.2Triacylglycerols211
9.3Polar Lipids216
9.4Steroids and Other Lipids219
9.5Biological Membranes225
9.6Membrane Transport229
9.7Examples of Membrane Transport232
Part IIIStorage and Transfer of Biological Information241
Chapter 10DNA and RNA: Structure and Function243
10.1RNA and DNA Chemical Structures244
10.2DNA Structural Elements251
10.3RNA Structural Elements258
10.4Cleavage of DNA and RNA by Nucleases261
10.5Nucleic Acid-Protein Complexes264
Chapter 11DNA Replication and Transcription: Biosynthesis of DNA and RNA271
11.1Replication of DNA272
11.2Action of DNA Polymerases277
11.3DNA Damage and Repair283
11.4Synthesis of RNA287
11.5Post-transcriptional Modification of RNA293
11.6Base Sequences in DNA298
Chapter 12Translation of RNA: The Genetic Code and Protein Metabolism305
12.1The Process of Protein Synthesis306
12.2The Three Stages of Protein Synthesis312
12.3Post-Translational Processing of Proteins320
12.4Regulation of Protein Synthesis and Gene Expression325
Chapter 13Recombinant DNA and Other Topics in Biotechnology337
13.1Recombinant DNA Technology338
13.2Preparing Recombinant DNA342
13.3DNA Amplification by the Polymerase Chain Reaction349
13.4Applications of Recombinant DNA Technology352
Part IVMetabolism and Energy363
Chapter 14Basic Concepts of Cellular Metabolism and Bioenergetics365
14.1Intermediary Metabolism368
14.2The Chemistry of Metabolism372
14.3Concepts of Bioenergetics379
Chapter 15Metabolism of Carbohydrates393
15.1The Energy Metabolism of Glucose395
15.2Entry of Other Carbohydrates into Glycolysis400
15.3Pyruvate Metabolism403
15.4Biosynthesis of Carbohydrates406
15.5Regulation of Carbohydrate Metabolism413
Chapter 16Production of NADH and NADPH: The Citric Acid Cycle, the Glyoxylate Cycle, and the Phosphogluconate Pathway423
16.1The Pyruvate Dehydrogenase Complex425
16.2The Citric Acid Cycle433
16.3The Citric Acid Cycle in Regulation and Biosynthesis438
16.4The Glyoxylate Cycle441
16.5The Phosphogluconate Pathway443
Chapter 17ATP Formation by Electron-Transport Chains449
17.1Mitochondrial Electron Transport450
17.2Components of the Electron-Transport Chain454
17.3Oxidative Phosphorylation459
17.4Recycling of Cytoplasmic NADH463
17.5Photosynthetic Electron Transport465
17.6Synthesis of Carbohydrates by the Calvin Cycle478
Chapter 18Metabolism of Fatty Acids and Lipids487
18.1Metabolism of Dietary Triacylglycerols488
18.2Catabolism of Fatty Acids493
18.3Biosynthesis of Fatty Acids502
18.4Cholesterol507
18.5Transport of Lipids in Blood514
Chapter 19Metabolism of Amino Acids and Other Nitrogenous Compounds523
19.1The Nitrogen Cycle524
19.2Biosynthesis of Amino Acids528
19.3Catabolism of Amino Acids532
19.4Elimination of NH[superscript + subscript 4]538
19.5Amino Acids as Precursors of Other Biomolecules541
Chapter 20Integration, Coordination, and Specialization in Metabolism557
20.1Overall Strategies of Metabolism558
20.2Metabolic Specialization and Integration561
20.3Metabolic Control by Hormones566
20.4Metabolic Responses to Stressful Conditions568
20.5Biochemical Factors in Obesity571
Glossary577
Answers to Study Exercises589
Credits615
Index617

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