Concepts in Clinical Pharmacokinetics / Edition 5

Concepts in Clinical Pharmacokinetics / Edition 5

by Joseph DiPiro
     
 


Short Description:
This popular teaching and self-instructional text makes it easier than ever to acquire a strong foundation in the basic principles of pharmacokinetics.See more details below

Overview


Short Description:
This popular teaching and self-instructional text makes it easier than ever to acquire a strong foundation in the basic principles of pharmacokinetics.

Product Details

ISBN-13:
9781585282418
Publisher:
American Society of Health-Systems Pharmacists
Publication date:
01/01/2010
Pages:
248
Product dimensions:
8.50(w) x 10.70(h) x 0.50(d)

Related Subjects

Table of Contents

Contents
Acknowledgments vii
Preface ix
Abbreviations xi
Lessons and Practice Sets
Lesson 1.
Introduction to Pharmacokinetics and Pharmacodynamics 1
Lesson 2.
Basic Pharmacokinetics 19
Lesson 3.
Half-Life, Elimination Rate, and AUC 29
Practice Set 1
43
Lesson 4.
Intravenous Bolus Administration, Multiple Drug
Administration, and Steady-State Average Concentrations 45
Lesson 5.
Relationships of Pharmacokinetic Parameters and
Intravenous Intermittent and Continuous Infusions 59
Lesson 6.
Two-Compartment Models 73
Practice Set 2
83
Lesson 7.
Biopharmaceutics: Absorption 87
Lesson 8.
Drug Distribution and Protein Binding 103
Lesson 9.
Drug Elimination Processes 113
Lesson 10.
Nonlinear Processes 131
vi Contents
Lesson 11.
Pharmacokinetic Variation and Model-Independent
Relationships 141
Practice Set 3
155
Lesson 12.
Aminoglycosides 159
Lesson 13.
Vancomycin 179
Lesson 14.
Theophylline 195
Lesson 15.
Phenytoin and Digoxin 203
Appendix A.
Basic and Drug-Specific Pharmacokinetic Equations 217
Appendix B.
Supplemental Problems 225
Appendix C.
Glossary 231
Index
233

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