Concise Guide to Drug Interaction Principles for Medical Practice: Cytochrome P450s, UGTs, P-Glycoproteins / Edition 2

Concise Guide to Drug Interaction Principles for Medical Practice: Cytochrome P450s, UGTs, P-Glycoproteins / Edition 2

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by Kelly L. Cozza, Scott C. Armstrong, Jessica R. Oesterheld
     
 

ISBN-10: 1585621110

ISBN-13: 9781585621118

Pub. Date: 01/28/2003

Publisher: American Psychiatric Publishing, Incorporated

The long-awaited Second Edition of this best-selling Concise Guide is here. Like the first edition of this unique pocket reference, the second edition is written expressly for clinicians. With four new contributors, this bestseller includes expanded sections on both phase I and phase II metabolism, updates of existing chapters and tables, new graphics, and

Overview

The long-awaited Second Edition of this best-selling Concise Guide is here. Like the first edition of this unique pocket reference, the second edition is written expressly for clinicians. With four new contributors, this bestseller includes expanded sections on both phase I and phase II metabolism, updates of existing chapters and tables, new graphics, and extensive website references. Brand-new chapters discuss P-glycoproteins, "minor" cytochrome P450 enzymes, pain management with narcotic and nonnarcotic analgesics, drug interaction assessment and prescribing guidelines, and medicolegal issues.

Following Part I, a succinct review of pharmacology, Part II contains pertinent tables, short reviews, and carefully chosen clinical and research illustrations (with case vignettes) for each P450 enzyme. In Part III, unique to this guide, the drugs used commonly in nonpsychiatric medicine that have clinically significant pharmacokinetic phase I, phase II, or P-glycoprotein drug interactions are arranged by specialty and listed in tables. Part IV focuses on practical matters, with chapters on drug interaction assessment and prescribing guidelines, medicolegal issues, and review and retrieval of the literature.

To enhance clinicians' use of this guide as a quick reference, the authors provide a pocket guide to the most common and potent inhibitors and inducers of drug metabolism, by enzyme system and by medical specialty.

Designed to enable psychiatrists to develop individualized tables and references for their own practices, this concise "how-to" guide will prove indispensable for students and practitioners in psychiatric (especially in complicated medical/surgical settings, such asgeriatrics) and nonpsychiatric (primary care, family practice, internal medicine, and obstetrics/gynecology) specialties alike.

Product Details

ISBN-13:
9781585621118
Publisher:
American Psychiatric Publishing, Incorporated
Publication date:
01/28/2003
Edition description:
Second Edition
Pages:
644
Product dimensions:
4.25(w) x 6.50(h) x 1.25(d)

Table of Contents

Introduction and Basic Pharmacology of Metabolic Drug Interactions. Introduction to drug interactions and to this concise guide. Definitions and phase I metabolism. Metabolism in depth: phase II. P-Glycoproteins. P450 Enzymes. 2D6. 3A4. 1A2. 2C9. 2C19. 2E1. P450 enzymes: 2A6, 2B6, 2C8. Drug Interactions by Medical Specialty. Gynecology: oral contraceptives. Internal medicine. Infectious diseases. Neurology. Oncology. Pain management I: nonnarcotic analgesics. Pain management II: narcotic analgesics. Psychiatry. Transplant surgery/rheumatology: immunosuppressants. Practical Matters. Guidelines. Medicolegal implications of drug-drug interactions. How to retrieve and review the literature. Appendix: trade and generic names used in this book. Index. Pull-out guide.

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Concise Guide to Drug Interaction Principles for Medical Practice: Cytochrome P450s, UGTs, P-Glycoproteins 5 out of 5 based on 0 ratings. 1 reviews.
Anonymous More than 1 year ago
I didn't realize that that the Concise Guide was actually the full book - although I should have gathered that from the word "Concise." I can't give it a bad star rating since I didn't end up keeping it. We wanted to order the full book and not the small copy. Just a heads up if you are looking for the same. Still haven't found a good place to order the actual book from. Sellers aren't always dependable on B&N.