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This is an authoritative and timely account of the two major weapons in the fight against virus disease: immunization and chemotherapy. The first half of the volume covers the development and the use of vaccines as part of an immunization program. The latter half examines the role of chemotherapy in the control and therapy of diseases such as influenza, hepatitis and AIDS. This book will be useful to clinical virologists, immunologists, epidemiologists and research scientists in chemotherapy, drug development and immunization.
Editors' preface; Part I. Immunisation: 1. Conventional viral vaccines and their influence on the epidemiology of disease J. L. Melnick; 2. Presentation of virus antigens for the induction of protective immunity R. E. Randall and B. E. Souberbielli; 3. Recombinant antigen production using baculovirus expression vectors R. D. Possee, U. Weyre and L. A. King; 4. Vaccinia: virus, vector and vaccine G. L. Smith; 5. Problems and prospects for synthetic peptide vaccines D. J. Rowlands; 6. Immunomodulation by adjuvants R. Bomford; 7. Factors influencing uptake of pre-school immunisation C. S. Peckham and H. E. Bedford; Part II. Chemotherapy: The importance of pathogenesis in the treatment of diseases caused by viruses K. McIntosh; 8. Virus replication and strategies for specific inhibition G. Darby; 9. Chemotherapy of influenza and respiratory viruses J. S. Oxford; 10. Management of chronic hepatitis virus infection H. C. Thomas; 11. Therapy - HIV D. D. Richman; 12. Herpes viruses in the immunocompromised host R. J. Whitley; 13. New developments in antiviral therapy J. Cameron.
Overview
This is an authoritative and timely account of the two major weapons in the fight against virus disease: immunization and chemotherapy. The first half of the volume covers the development and the use of vaccines as part of an immunization program. The latter half examines the role of chemotherapy in the control and therapy of diseases such as influenza, hepatitis and AIDS. This book will be useful to clinical virologists, immunologists, epidemiologists and research scientists in chemotherapy, drug development and...