Cryopreservation and low temperature biology in blood transfusion: Proceedings of the Fourteenth International Symposium on Blood Transfusion, Groningen 1989, organised by the Red Cross Blood Bank Groningen-Drenthe / Edition 1

Cryopreservation and low temperature biology in blood transfusion: Proceedings of the Fourteenth International Symposium on Blood Transfusion, Groningen 1989, organised by the Red Cross Blood Bank Groningen-Drenthe / Edition 1

by Cees Smit Sibinga
     
 

ISBN-10: 0792309081

ISBN-13: 9780792309086

Pub. Date: 10/31/1990

Publisher: Springer US

Product Details

ISBN-13:
9780792309086
Publisher:
Springer US
Publication date:
10/31/1990
Series:
Developments in Hematology and Immunology (closed) Series, #24
Edition description:
1990
Pages:
291
Product dimensions:
6.14(w) x 9.21(h) x 0.36(d)

Table of Contents

I. Principles and fundamentals.- Metabolism and physiology of cells at low temperatures.- Freezing and thawing plasma.- Cell and cell constituent freeze-drying: fundamentals and principles.- Freezing versus vitrification; basic principles.- Ice nucleation and growth in vitrifiable solutions.- Liposomes as a model system for the cryopreservation of peripheral blood cells.- Discussion.- II. Low temperature biology aspects.- Storage media for red cells.- Prolonged storage of adult and newborn red cells.- Extended storage of (washed) red cells at 4°C.- Storage of platelet concentrates in plasma-free synthetic media.- Separation and purification of cold insoluble globulines.- New solution for organ preservation.- Discussion.- III Cryopreservation aspects.- Platelet freezing.- Platelet freezing: the effect of some additives.- Inexpensive method for cryopreservation of human peripheral blood lymphocytes.- Cryopreservation of human stem cells.- Preservation and storage of human blood plasma proteins.- Residual water content in a lyophilized, heated coagulation factor concentrate.- Discussion.- IV. Advances and clinical applications.- Clinical application of cryopreserved stem cells and platelets in a bone marrow transplant program.- Clinical efficacy of cryopreserved bone.- Vitrification as an approach to organ cryopreservation: past, present, and future.- Transfusion, transplantation and the immunological revolution.- Discussion.

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