Crystallography / Edition 1

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Overview

Richly illustrated throughout, this book provides a comprehensive, approachable summary of the field of crystallography, fundamental theory of diffraction and properties of crystals, applications in determining macromolecular structure. Dedicated to providing a complete introduction to the subjectthat does not assume a background in physics or math, book?s contents flow logically from basic principles to methods, such as those for solving phase problems, interpretation of Patterson maps, and the difference Fourier method. This introduction includes practical instruction on interpretation of data and methods for determining phases and also:?
  • Illustrates concepts throughout to clarify difficult ideas
  • Integrates analogies to illuminate the text
  • Equips the reader to employ the range of programs in crystallography
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Editorial Reviews

From the Publisher
"…provides an up-to-date overview of the different phases of drug discovery and preclinical development of experimental cancer principles.” (Drug Discovery & Development, September 2004)

"…benefits source: strong writing and a gifted use of analogy to introduce the abstract issues…perfect for a novice…" (Journal of Chemical Education, Vol. 80, No. 9 September 2003)

"...an excellent introductory text..." (Journal of Proteome Research, Vol. 2, No. 2, March/April 2003)

"...this welcome addition to the introductory crystallographic literature should be well received…recommended..." (Choice, Vol. 40, No. 8, April 2003)

"...an excellent introductory text..." (Journal of Proteome Research, Vol. 2, No. 2, March/April 2003)

"...this welcome addition to the introductory crystallographic literature should be well received...recommended..." (Choice, Vol. 40, No. 8, April 2003)

"...I highly recommend this book...in fact, I foresee it finding its way to the bookshelves of many faculty members, albeit with frequent removal for consultation as an educational tool!" (Clinical Chemistry, Vol. 49, No. 7, 2003)

"...excellent and clear introduction...in an easily readable and conversational style it explains many essential principles and methods very effectively..." (Angewandte Chemie International Edition, Vol 42(37), 2003)

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Product Details

  • ISBN-13: 9780471251224
  • Publisher: Wiley, John & Sons, Incorporated
  • Publication date: 10/11/2002
  • Edition description: Older Edition
  • Edition number: 1
  • Pages: 256
  • Product dimensions: 10.00 (w) x 7.00 (h) x 0.53 (d)

Meet the Author

Alexander Mcpherson, PhD, is Professor in the Department of Molecular Biology and Biochemistry at the University of California, Irvine's School of Biological Sciences. The author of six books and 300 papers or reviews, he is widely considered the nation's foremost authority in the field of macromolecular crystallography. For over a decade, he has served as principal instructor of the Cold Spring Harbor Laboratory course inmacromolecular X-ray crystallography, an intensive course for which much of the material in this text was originally conceived.

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Table of Contents

Preface.

An Overview of Macromolecular Crystallography.

The Nature of Crystals: Symmetry and the Unit Cell.

Waves and Their Properties.

Diffraction from Points, Planes, Molecules, and Crystals.

Examination of Diffraction Patterns.

Solving the Phase Problem.

Interpreting Patterson Maps.

Electron Density Maps and Difference Fourier Maps.

Bibliography.

Index.

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Sort by: Showing 1 Customer Reviews
  • Anonymous

    Posted April 24, 2003

    Masterful

    '...a masterful presentation of the theory and practice of crystallography as applied to large molecules. Any student or professional who wants to deepen his or her understanding of the field should work through this text. The clarity, completeness, and simplicity of [Dr. McPherson's] treatment are impressive.' -Andrew J.Howard, Argonne National Laboratory, Argonne, Illinois, and Illinois Institute of Technology, Chicago, Illinois

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