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Doody's Review ServiceReviewer: James G Douglas, MD, MS (Memorial Hospital of Sweetwater County)
Description: This second volume in the series, Cancer Survivorship Research and Education, covers the late effects on normal tissues of radiotherapy.
Purpose: The book examines mechanisms of action and causes of both early and late radiotherapy consequences. These concepts are of enormous importance for oncologists and the authors clearly accomplish their objective.
Audience: Written for oncologists, particularly radiation oncologists, the book is appropriate for attendings, residents, and fellows in all oncology specialties. The authors/contributors are world leaders in oncology.
Features: The book covers the basics of radiation-induced damage; the molecular mechanisms of damage and rationales for biointervention; the concept of bioengineering to assist in the repair of radiation damage; the use of bioimaging to discern the evolution of late effects; selected specific organ toxicities (brain, cardiac) and strategies to abrogate the effect of irradiation; toxicity from hypofractionated (SBRT) treatment paradigms; and second malignancies in prostate and stem-cell transplanted patients. The figures and tables are well designed and the print quality is excellent.
Assessment: This is a very well organized and written book, succinct yet strikingly informative. This series should be in every radiation oncologist's personal library and is full of insight for those in other oncology specialties.