Cured: The People Who Defeated HIV
“Nathalia Holt presents a thorough account of the research that provides scientists with hope that a cure will one day be achievable... and her empathy shines through in her prose. This is as important a social history as it is a medical document.”—The Daily Beast
 
Two patients—each known in medical history as the Berlin Patient—were cured of the HIV virus. The two patients’ disparate cures came twelve years apart, but Nathalia Holt, an award-winning scientist at the forefront of HIV research, connects the molecular dots of these cases for the first time.
 
Scientists are known to maintain a professional distance from those they study, but sometimes scientists are not just investigators, they are caregivers, too. Cured illustrates that even in the era of high-tech and big pharma, the way doctors and patients communicate remains a critical ingredient in the advance of this science. Holt offers a kind of hope that the thirty-four million people currently infected with HIV need and a story of ingenuity, dedication, and humanity that will inspire the rest of us.
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Cured: The People Who Defeated HIV
“Nathalia Holt presents a thorough account of the research that provides scientists with hope that a cure will one day be achievable... and her empathy shines through in her prose. This is as important a social history as it is a medical document.”—The Daily Beast
 
Two patients—each known in medical history as the Berlin Patient—were cured of the HIV virus. The two patients’ disparate cures came twelve years apart, but Nathalia Holt, an award-winning scientist at the forefront of HIV research, connects the molecular dots of these cases for the first time.
 
Scientists are known to maintain a professional distance from those they study, but sometimes scientists are not just investigators, they are caregivers, too. Cured illustrates that even in the era of high-tech and big pharma, the way doctors and patients communicate remains a critical ingredient in the advance of this science. Holt offers a kind of hope that the thirty-four million people currently infected with HIV need and a story of ingenuity, dedication, and humanity that will inspire the rest of us.
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Cured: The People Who Defeated HIV

Cured: The People Who Defeated HIV

by Nathalia Holt
Cured: The People Who Defeated HIV

Cured: The People Who Defeated HIV

by Nathalia Holt

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Overview

“Nathalia Holt presents a thorough account of the research that provides scientists with hope that a cure will one day be achievable... and her empathy shines through in her prose. This is as important a social history as it is a medical document.”—The Daily Beast
 
Two patients—each known in medical history as the Berlin Patient—were cured of the HIV virus. The two patients’ disparate cures came twelve years apart, but Nathalia Holt, an award-winning scientist at the forefront of HIV research, connects the molecular dots of these cases for the first time.
 
Scientists are known to maintain a professional distance from those they study, but sometimes scientists are not just investigators, they are caregivers, too. Cured illustrates that even in the era of high-tech and big pharma, the way doctors and patients communicate remains a critical ingredient in the advance of this science. Holt offers a kind of hope that the thirty-four million people currently infected with HIV need and a story of ingenuity, dedication, and humanity that will inspire the rest of us.

Product Details

ISBN-13: 9780142181843
Publisher: Penguin Publishing Group
Publication date: 02/24/2015
Pages: 336
Product dimensions: 5.30(w) x 7.80(h) x 0.90(d)
Age Range: 18 Years

About the Author

Nathalia Holt trained at Massachusetts General Hospital, MIT, Harvard University, the University of Southern California, and Tulane University. She lives with her family in Boston.

Table of Contents

Cast of Characters xi

Preface xiii

Part I A Doctor, Two Patients, and Some Tests

Chapter 1 The Good Doctor in Denial 3

Chapter 2 A Visit with the Family Doctor 13

Chapter 3 Death Sentence? 21

Part II The Disease, a Drug, and Its Industry

Chapter 4 Viral Trojan Horse 33

Chapter 5 A Weapon from the War on Cancer 43

Chapter 6 The Days of Acting Up 57

Chapter 7 Recognizing a Global Pandemic 65

Chapter 8 From the One Percent 79

Chapter 9 But, Doctor, 1 Don't Feel Sick 87

Chapter 10 The Delta 32 Mutation 95

Chapter 11 Calling All Elite Controllers 99

Chapter 12 Treatment in Hiding 111

Part III Treating the Berlin Patients

Chapter 13 The Second Diagnosis 119

Chapter 14 The Compassionate Use Exemption 131

Chapter 15 Three Deadly Diseases Move In 135

Chapter 16 The Comfort of family and Strangers 141

Chapter 17 Timing 147

Chapter 18 Transplanting 153

Chapter 19 "Perhaps We Have Eradicated HIV" 163

Chapter 20 An Unexciting Recovery 175

Part IV The Cure

Chapter 21 Trials 185

Chapter 22 Proof of Principle 199

Chapter 23 The Good Doctor in Court 205

Chapter 24 Not Even Surprising 209

Chapter 25 The Promise Kept 221

Chapter 26 A Child Cured-So What? 241

Chapter 27 Zinc Finger Snap 249

Chapter 28 The Abused, the Respected, the Relentless 261

Notes 273

Timeline 297

Acknowledgments 299

Index 303

What People are Saying About This

From the Publisher

Praise for Cured

“It’s one of the most incredible stories in medical science: a cure for HIV.  Nathalia Holt tells the personal stories of the patients, their families, and their doctors.”—National Geographic

“One learns fascinating details about AIDS and shares Holt’s hope…She is among those working to make the promise real”—New York Times Book Review

“Nathalia Holt presents a thorough account of the research that provides scientists with hope that a cure will one day be achievable... and her empathy shines through in her prose. This is as important a social history as it is a medical document.”—The Daily Beast

"In this accessible and fascinating account, Holt, a research scientist trained at MIT and Harvard...brings to light the remarkable early breakthroughs in treating a once fatal condition." - Publishers Weekly

"A fascinating discourse on how medical science is zeroing in on an HIV vaccine after several anomalous triumphs...An astute AIDS retrospective blended with contemporary updates on aggressive medical strategies." - Kirkus Reviews

“In this exquisitely detailed telling of medicine's desperate fight to control the HIV epidemic, author Nathalia Holt reminds us that all the best medical stories are foremost stories of people - their determination, their courage, and their ability, in the best of circumstances, to rewrite history in a way that protects us all.”—Deborah Blum, author of The Poisoner's Handbook

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