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Current Concepts in Drug Metabolism and Toxicology [NOOK Book]

Overview

This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. With a variety of chapters and the best authors in the ...

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Current Concepts in Drug Metabolism and Toxicology

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Overview

This new volume of Advances in Pharmacology explores the current concepts in drug metabolism and toxicology. Chapters cover the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity. With a variety of chapters and the best authors in the field, the volume is an essential resource for pharmacologists, immunologists and biochemists alike.



  • Explores the current concepts in drug metabolism and toxicology
  • Chapters cover such areas as the Keap1-Nrf2 cell defense pathway, animal models of drug-induced idiosyncratic toxicity and the use of human embryonic and induced pluripotent stem cells for modeling metabolism and toxicity
  • An essential resource for pharmacologists, immunologists and biochemists alike
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Product Details

  • ISBN-13: 9780123983596
  • Publisher: Elsevier Science
  • Publication date: 11/27/2012
  • Sold by: Barnes & Noble
  • Format: eBook
  • Pages: 304
  • File size: 5 MB

Table of Contents

  1. Membrane Transporters in Drug Development
  2. The Keap1-Nrf2 Cell Defence Pathway - A Promising Therapeutic Target?
  3. Animal Models of Idiosyncratic Drug Reactions
  4. Genetic Polymorphisms Affecting Drug Metabolism: Recent Advances and Clinical Aspects
  5. Arylamine N-Acetyltransferases - from Drug Metabolism and Pharmacogenetics to Identification of Novel Targets for Pharmacological Intervention
  6. Human Pluripotent Stem Cells for Modelling Toxicity
  7. Disposition of Biologics
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