Cytotoxins and Immunotoxins for Cancer Therapy: Clinical Applications by Koji Kawakami | Hardcover | Barnes & Noble
Cytotoxins and Immunotoxins for Cancer Therapy: Clinical Applications

Cytotoxins and Immunotoxins for Cancer Therapy: Clinical Applications

by Koji Kawakami
     
 

ISBN-10: 0415263654

ISBN-13: 9780415263658

Pub. Date: 10/27/2004

Publisher: Taylor & Francis

With the advent of advances in immunotoxicity, the promise of 'smart bomb' cancer therapies has been dawning for some time. Now, the first of these drugs has been approved by the FDA, and it is hoped that this will accelerate our understanding of cancer and lead to further treatments with the same approach. In this state of the art book, Raj Puri brings together

Overview

With the advent of advances in immunotoxicity, the promise of 'smart bomb' cancer therapies has been dawning for some time. Now, the first of these drugs has been approved by the FDA, and it is hoped that this will accelerate our understanding of cancer and lead to further treatments with the same approach. In this state of the art book, Raj Puri brings together leading researchers to discuss clinical trial data concerning some of the most widely studied tumors. Researchers in cancer therapy, oncologists and immunologists have, in this single resource, access to important data and far-sighted thinking.

Product Details

ISBN-13:
9780415263658
Publisher:
Taylor & Francis
Publication date:
10/27/2004
Series:
Pharmaceutical Science Series
Pages:
244
Product dimensions:
6.40(w) x 9.60(h) x 0.72(d)

Table of Contents

Preface: An Overview of Immunotoxins and Cytotoxins in Clinical Trials
PART 1. PSEUDOMONAS EXOTOXIN (PE)-BASED IMMUNOTOXINS/CYTOTOXINS
Targeting of Pseudomonas Exotoxin-based Immunotoxins to Hematologic Malignancies, Robert J. Kreitman
Interleukin-4-targeted Cytotoxin for Recurrent Glioblastoma Therapy, Koji Kawakami, Mariko Kawakami, Robert J. Kreitman, and Raj K. Puri
Interleukin-13 Receptors and Development of IL-13-Pseudomonas Exotoxin for Human Cancer Therapy, Bharat H. Joshi, Syed R. Husain, Pamela Leland, and Raj K. Puri

PART 2. RICIN-BASED IMMUNOTOXINS/CYTOTOXINS
Ricin Immunotoxins in Lymphomas, Ronald Schnell and Andreas Engert

PART 3. DIPHTHERIA TOXIN (DT)-BASED IMMUNOTOXINS/CYTOTOXINS
Diphtheria-based Immunotoxins: Targeting Overexpressed Interleukin-13 Receptor and Urokinase-type Plasminogen Activator Receptor on Glioblastoma Multiforme, Edward Rustamzadeh, Walter A. Hall, Deborah Todhunter, and Daniel Vallera
DAB389IL-2 (Ontak): Development and Therapeutic Applications, Paul J. Shaughnessy, and Charles F. LeMaistre
Transferrin Diphtheria Toxin for Brain Tumor Therapy, Simon Long and Patrick Rossi
GM-CSF Receptor Targeted Therapy of Human Leukemia, Arthur E. Frankel, Philip D. Hall, Dongsun Cao, Tie Fu Liu, Marlena Moors, Kimberley A. Cohen, Andrew M. Thorburn, and Robert J. Kreitman
VEGF-diphtheria toxin for Targeting of Tumor Blood Vessels, Indira V. Subramanian, and Sundaram Ramakrishnan

PART 4. MISCELLANEOUS
cBR-96-doxorubicin (SGN-15) for Metastatic Breast Cancer Therapy, Lisle Nabell, Clay B. Siegall, and Mansoor N. Saleh
Anti-CD33 Calicheamicin Immunoconjugate Therapy of Acute Myeloid Leukemia, Charalambos Andreadis, Selina M. Luger Selina, and Edward A. Stadtmauer

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