Signals of minimal supersymmetric models with non-universalities in the gaugino sector of the theory are analyzed at the CERN Large Hadron Collider (LHC) and in experiments searching for dark matter. Signals of dark matter including direct and indirect detection are investigated at depth in various supersymmetric frameworks. The parameter space of deflected mirage mediation, in which the soft terms receive contributions from the three main supersymmetry breaking mediation mechanisms, is investigated with emphasis on the neutralino sector and dark matter signals. The potential for non-universal gaugino masses to explain the recent CDMS II data is studied and possible implications for indirect dark matter detection experiments and LHC signatures are considered. Collider implications of non-universalities in the gaugino sector are examined with attention paid to specific signatures which are targeted to track the non-universalities. Further, the complementarity of dark matter and collider measurements is discussed with emphasis on breaking model degeneracies which may arise in LHC data.