Deadly Choices: How the Anti-Vaccine Movement Threatens Us All

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Overview

In 2010, California suffered the largest and deadliest outbreak of pertussis, also known as “whooping cough,” in more than fifty years. This tragedy was avoidable. An effective vaccine has been available since the 1940s. In recent years other diseases, like measles and mumps, have also made a comeback. The reason for these epidemics can be traced to a group whose vocal proponents insist, despite evidence to the contrary, that vaccines are poison. As a consequence, parents and caretakers are rejecting vaccines for themselves and their families.

In Deadly Choices, infectious-disease expert Paul Offit takes a look behind the curtain of the anti-vaccine ...

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Overview

In 2010, California suffered the largest and deadliest outbreak of pertussis, also known as “whooping cough,” in more than fifty years. This tragedy was avoidable. An effective vaccine has been available since the 1940s. In recent years other diseases, like measles and mumps, have also made a comeback. The reason for these epidemics can be traced to a group whose vocal proponents insist, despite evidence to the contrary, that vaccines are poison. As a consequence, parents and caretakers are rejecting vaccines for themselves and their families.

In Deadly Choices, infectious-disease expert Paul Offit takes a look behind the curtain of the anti-vaccine movement. What he finds is a reminder of the power of scientific knowledge, and the harm we risk if we ignore it.

Editorial Reviews

Publishers Weekly
In the second book this season (after journalist Seth Mnookin's The Panic Virus) to attack vaccine paranoia, Offit—who drew antivaccinist fire for Autism's False Prophets—presents a smart, hard-hitting exposé of vaccine pseudoscience. Offit brings outstanding credentials to the subject: he's a vaccinologist at Children's Hospital in Philadelphia and an expert in infectious diseases, and he tackles claims that childhood inoculations cause brain damage, autism, diabetes, and cancer, finding a farrago of misinformation, faulty research, and sly deceptions fed to distraught parents by media hype, ax-grinding activists, and personal-injury lawyers. He embellishes his account with a sprightly history of paranoid medical populism—19th-century critics of the cowpox-derived smallpox vaccine insisted it could turn people into cows—and a blistering attack on celebrity antivaccine ideologues Jenny McCarthy, Jim Carrey, and Bill Maher and the medical writers who pander to parental anxieties. Offit dwells less than Mnookin on the sociology of the controversy and more on the science. The result is a thorough dismantling of antivaccine notions and a sober warning about the resurgence of deadly childhood infections stemming from declining vaccination rates. Worried parents, especially, will find this a lucid, compelling riposte to antivaccine fear-mongering. Photos. (Feb.)
Kirkus Reviews

Offit (Vaccinology and Pediatrics/Univ. of Pennsylvania; Autism's False Prophets: Bad Science, Risky Medicine, and the Search for a Cure, 2008, etc.) takes aim at the anti-vaccine movement in America and scores a bull's-eye.

If only people would listen. Unfortunately, it's often a case of irrational behavior fueled by hostility toward doctors, researchers, drug companies and government. The issue comes down to coincidence vs. causality. A baby is vaccinated and thereafter develops seizures, brain damage, autism or other disorders. So powerful is the need to find a cause that vaccines become the target and no amount of clinical or epidemiological evidence will change opinions. Abetting belief are the activists and celebrities who champion the cause on the nightly news or on their own inflammatory blogs. What Offit offers in response is a well-documented history dating back to the first vaccine for smallpox. That, too, occasioned widespread attack once vaccination was made compulsory, with protesters even claiming that children would develop little cows at the inoculation site (because the vaccine is based on the cowpox virus. The author traces recent anti-vaccine activism in America to the 1982 documentaryDPT: Vaccination Roulette, which inveighed against the pertussis part of the DPT regimen (diphtheria, pertussis, tetanus). In spite of exonerating evidence, negative publicity and lawsuits drove drug companies out of the vaccine business and led to the National Childhood Vaccine Injury Act. But the battle was renewed with the association between autism and the measles, mumps and rubella vaccine or its mercury component. Now that vaccine is mercury-free, and countless studies have discounted any association, but the protests mount, with many states allowing parents to opt out of vaccine programs. The danger is that with too many kids unvaccinated, herd immunity is lost and epidemics become a reality. Offit rightly points out that it would be a mistake to go this route to demonstrate why vaccines are essential; what we need is a restoration of trust. He suggests that this could happen if concerned parents and public health workers who have seen the devastation wrought by childhood disease speak out.

A much-needed book with solid evidence—deserves all the publicity it can get.

Product Details

  • ISBN-13: 9780465029624
  • Publisher: Basic Books
  • Publication date: 4/3/2012
  • Edition description: First Trade Paper Edition
  • Pages: 288
  • Sales rank: 264,496
  • Product dimensions: 5.50 (w) x 8.10 (h) x 0.80 (d)

Meet the Author

Paul A. Offit, MD is the Chief of the Division of Infectious Diseases and the Director of the Vaccine Education Center at the Children’s Hospital of Philadelphia. He is the Maurice R. Hilleman Professor of Vaccinology and a Professor of Pediatrics at the University of Pennsylvania School of Medicine. Dr. Offit is a founding advisory board member of the Autism Science Foundation—to which he is donating the royalties from this book—and the author of five books including Autism’s False Prophets and Vaccinated. He lives in Bala Cynwyd, Pennsylvania.

Table of Contents

Prologue ix

Introduction xi

1 The Birth of Fear 1

2 This England 13

3 A Crude Brew 25

4 Roulette Redux 45

5 Make the Angels Weep 57

6 Justice 85

7 Past Is Prologue 105

8 Tragedy of the Commons 127

9 The Mean Season 149

10 Dr. Bob 171

11 Trust 191

Epilogue 207

Notes 215

Selected Bibliography 255

Acknowledgments 257

Index 259

Customer Reviews

Average Rating 4.5
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  • Posted January 1, 2011

    a compelling review of the history of anti-vaccine movements

    The focus of Deadly Choices is on the history of the introduction of new vaccines and the anti-vaccine movements that tend to follow. Offit is a prominent virologist and he doesn't hide his scorn for some in the anti-vaccine movement. His book is unlikely to change the minds of anyone who is firmly within that movement, but I'm not sure what would. The book is a must read for anyone interested in a detailed, well-written, and thoroughly sourced discussion of the scientific basis of vaccines, the real and imagined risks of vaccination, and the consequences of the choices we make about vaccines. The book thoroughly documents some of the unfounded claims that the anti-vaccine movement has made and explains the biological reasons why some of the perceived risks of vaccines either are not a risk or physiologically CAN'T be a risk. The book is not one-sided, though. The first chapters discuss all of the well-documented cases of actual vaccine injury and the real side effects of vaccines (e.g., the live polio vaccine could cause polio, although most vaccines don't use live viruses). Offit makes the case that anti-vaccine movements raise fears of vaccines that are inconsistent with the science. In so doing, he draws parallels between current anti-vaccine claims and those made over a century ago after the introduction of the smallpox vaccine. Many of the fears of that vaccine are laughable by today's standards (e.g., that children would develop cow-like facial features because the vaccine was initially taken from cows infected by cowpox). But Offit argues, fairly convincingly, that the logic and nature of current anti-vaccine scares are largely the same as those raised over a century ago and in each subsequent anti-vaccine movement. The most compelling chapter is the last one, in which Offit describes what happens when someone who could not be vaccinated (because they were too young) comes into contact with an infected child whose parents decided not to vaccinate. The choice not to vaccinate affects people other than your own child--it puts young infants and others whose bodies lack a typical immune response can't be vaccinated at risk. The chapter is reminiscent of the recent PBS Frontline documentary on vaccinations. At times, the book can be a bit heavy handed in its tone-Offit's perspective is clear throughout, and he doesn't hold his punches. Sometimes his parallels between historical anti-vaccine movements and current ones are a little forced, and in a few cases, the book is perhaps a bit more dismissive than is necessary. Overall, though, the book presents the scientific evidence in a compelling, comprehensive, thoroughly documented, and engaging way. For prospective parents whose prior information about vaccines comes from friends, the internet, or even their pediatrician, this book is a must read by one of the top scientific experts in the field. It provides the background and evidence you need to evaluate claims about the dangers and benefits of vaccines and to make the best choice for your children AND your community.

    3 out of 4 people found this review helpful.

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