Dementia: Presentations, Differential Diagnosis, and Nosology / Edition 2

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Overview

In this new edition of the acclaimed Dementia: Presentations, Differential Diagnosis, and Nosology, V. Olga B. Emery, Ph.D., and Thomas E. Oxman, M.D., bring together a distinguished group of medical authorities—including many who have done seminal research in this field—to discuss the spectrum of dementing disorders and explain their overlap, presentations, and differential diagnosis. The chapters present original data as well as material from the authors' clinical experiences. Current classification systems are evaluated and modified to better account for common presentations of dementia.

Thoroughly revised, updated, and expanded, the second edition includes new material on neuroimaging, genetics, the role of inflammation in Alzheimer disease, retrophylogenesis in Alzheimer memory, and on AIDS dementia. In addition, each chapter includes a new section entitled describing clinical applications.

Johns Hopkins University Press

Incl. construct, nosologic validity/diagnostic procedures/ Alzheimer's, vascular. subcortical, and depressive dementias

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Editorial Reviews

Doody's Review Service
Reviewer: David O. Staats, MD (University of Oklahoma Health Sciences Center)
Description: This is the second edition of a multiauthored textbook on dementing illnesses first published in 1994.
Purpose: The purpose of this book is to show the spectrum of dementing illnesses, how they evolve through time, and what their nature is: contrasting, overlapping, and differentiating.
Audience: This is not a book for beginners; it is not a primer of dementing illnesses. Rather, it is for those who have advanced knowledge about dementing illnesses, who can grasp the challenges of differentiating one from another. I think that this book is aimed at neurologists, psychologists, and psychiatrists and basic science researchers in the areas of dementing illnesses. All the authors are experts in the field.
Features: New in this book are discussions of how HIV-AIDS dementia fits into the spectrum of dementing illnesses and a new model of the unraveling of memory and higher cortical functions that accompanies dementing illnesses. The discussions about what separates normal age-related changes in cognitive function from "mild cognitive impairment" to frank dementing illnesses is thoughtfully portrayed and thorough. The discussions about what the nature of vascular dementias, their antecedent "preinfarction state" is also quite on the mark.
Assessment: This is unlike any other book in the areas that it covers. The clinical synopses at the ends of the chapters are a little superficial. At times the beauty of the conceptualization is like viewing a Turner landscape; at other times the writing borders on the verbose. This book draws together much difficult information together and shows how much work is left to be done. That it emphasizes how dementing illnesses evolve over time is much to its credit.
New England Journal of Medicine
A forward-thinking contribution to the field of dementia and is commendable for its goal of striving beyond overly simplistic, formulaic conventions. It would be well placed on the library shelf of the curious and contemplative cognitive clinician.

— Daniel Kaufer, M.D.

Canadian Journal of Psychiatry
A major contribution to dementia research... An excellent reference text for those exploring both the uncharted areas of research and some of the clinical aspects of dementia.

— Matthew Robillard, MD

American Journal of Psychiatry
A valuable addition to our understanding of the conditions that erode our memory.

— Frances R. Frankenburg, M.D.

International Psychogeriatrics
Timely publication... Stimulating and thorough coverage.

— Mark Walterfang

American Journal of Geriatric Psychiatry
A thorough, current discussion of the various aspects of dementia, possibly the best now available.

— Roy R. Reeves

Contemporary Gerontology
A major contribution to dementia research... Should be read by all scientists and clinicians interested in these important diseases associated with aging.

— Robert M. Schmidt

Journal of the American Geriatrics Society
Emery and Oxman have done a valuable service by documenting the pitfalls in our current understanding of dementia. They are preparing the way for a new synthesis.

— Donald R. Royall

New England Journal of Medicine - Daniel Kaufer

A forward-thinking contribution to the field of dementia and is commendable for its goal of striving beyond overly simplistic, formulaic conventions. It would be well placed on the library shelf of the curious and contemplative cognitive clinician.

Canadian Journal of Psychiatry - Matthew Robillard

A major contribution to dementia research... An excellent reference text for those exploring both the uncharted areas of research and some of the clinical aspects of dementia.

American Journal of Psychiatry - Frances R. Frankenburg

A valuable addition to our understanding of the conditions that erode our memory.

International Psychogeriatrics - Mark Walterfang

Timely publication... Stimulating and thorough coverage.

American Journal of Geriatric Psychiatry - Roy R. Reeves

A thorough, current discussion of the various aspects of dementia, possibly the best now available.

Contemporary Gerontology - Robert M. Schmidt

A major contribution to dementia research... Should be read by all scientists and clinicians interested in these important diseases associated with aging.

Journal of the American Geriatrics Society - Donald R. Royall

Emery and Oxman have done a valuable service by documenting the pitfalls in our current understanding of dementia. They are preparing the way for a new synthesis.

Manchester Royal InfirmaryInternational Journal of Peter Ocansey

This book is authoritative on the subject of dementia and every clinician who sees patients with this rather debilitating and progressive illness will find this very resourceful. Once you start reading you feel compelled to continue turning the pages till the very last.

Booknews
An empirical, clinical, and theoretic discussion of the presentations, differential diagnosis, and nosology of dementia. It advances a spectrum approach to the dementias--each dementing illness involving an array of varied but related presentation, that form a continuous series. The contributors present new material, integrate what is known, and point to future work needed to clarify fundamental relationships between the dementias. The volume is divided into five sections: background, concepts, and diagnostics; Alzheimer dementias; vascular dementias and subcortical dementias; depressive dementia; and conclusions and future directions. Annotation c. Book News, Inc., Portland, OR (booknews.com)
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Product Details

Meet the Author

V. Olga B. Emery, Ph.D., is an adjunct associate professor of psychiatry at Dartmouth Medical School and director of the New Hampshire Center on Aging, Health and Society. She also holds an appointment at Harvard Medical School. Thomas E. Oxman, M.D., is a professor of psychiatry and community and family medicine at Dartmouth Medical School.

Johns Hopkins University Press

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Table of Contents

Contents:List of Contributors

Acknowledgments

List of Abbreviations

IntroductionPART ONE: Background, Concepts, and Diagnostics1. Boundaries between Normal Aging and Dementia: Perspectives from Neuropsychological and Neuroimaging Investigations

2. The Spectrum of Dementias: Construct and Nosologic Validity

3. Diagnostic Procedures for Dementia

PART TWO: Alzheimer Dementias4. The Neuropathology of Alzheimer Dementia

5. Neural Inflammatory Mechanisms in Alzheimer Syndrome

6. Clinical Subgroups of Alzheimer Disease

7. Progressive Aphasia, Frontotemporal Dementia and Other "Focal Dementias"

8. "Retrophylogenesis" of Memory in Dementia of the Alzheimer Type: A New Evolutionary Memory FrameworkPART THREE: Vascular Dementias and Subcortical Dementias9. Cortical and Frontosubcortical Dementias: Differential Diagnosis

10. Noninfarct Vascular Dementia: The Spectrum of Vascular Dementia and Alzheimer Syndrome

11. The Relationship of Hypertension to Vascular Dementia

12. Vascular Dementias and Alzheimer Disease: Differential Diagnosis

13. Acquired Immunodeficiency Syndrome Dementia ComplexPART FOUR: Depressive Dementias14. Depressive Dementia: A "Prepermanent Intermediate-stage Dementia" in a Long-term Disease Course of Permanent Dementia?

15. Depressive Dementia: Cognitive and Biological Correlated and Course of Illness

16. The Nondepressive Pseudodementias

17. Neurobiology of Major Depression in Alzheimer Disease

18. Approaches to the Treatment of Dementing Illness

19. The Spectra of the Dementias

Index

Johns Hopkins University Press

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