Table of Contents
List of Contributors, vii
Preface, x
Section 1 Dermatology and Oncology
1 Epidemiology and Burden of Disease, 3Beth N. McLellan, Devika Patel and Mario E. Lacouture
2 The History of Supportive Oncodermatology, 17Yevgeniy Balagula, Steven T. Rosen and Mario E. Lacouture
3 Structure and Function of the Integumentary System and the Dermatology Lexicon, 24Emmy Graber and Amit Garg
4 Types of Dermatologic Reactions, 33Raed O. Alhusayen, Sandra R. Knowles and Neil H. Shear
5 Grading Dermatologic Adverse Events in Clinical Trials Using CTCAE v4.0, 47Alice Chen, Asha Acharya and Ann Setser
6 Psychosocial Issues in Oncology: Clinical Management of Psychosocial Distress, Health-Related Quality of Life, and Special Considerations in Dermatologic Oncology, 60Lynne I. Wagner and David Cella
7 Dermatopathology, 69Molly A. Hinshaw and James L. Troy
Section 2 Cancer-Related Dermatologic Disorders
8 Paraneoplastic, Inherited Cancer Syndrome, and Environmental Carcinogen-Related Dermatoses, 77Cindy England Owen and Jeffrey P. Callen
Section 3 Dermatologic Conditions During Cancer Therapy
9 Oral Mucosal Complications of Cancer Therapy, 89Stephen T. Sonis
10 Hair Disorders Associated with Anticancer Agents, 100Caroline Yeager and Elise A. Olsen
11 Nail Abnormalities in Oncology Practice, 115Robert Baran, Bernard Fouilloux and Caroline Robert
12 Pruritus, 122Tejesh Patel and Gil Yosipovitch
13 Management Options for Hot Flashes in Cancer Patients, 131Amanda R. Moraska and Charles L. Loprinzi
Section 4 Skin Toxicities to Chemotherapy
14 Alkylating Agents, 147Elisabeth Livingstone, Lisa Zimmer, Larissa Leister and Dirk Schadendorf
15 Antimetabolite Reactions, 160Emily Y. Chu and Heidi H. Kong
16 Topoisomerase-Interacting Agents, 170Tomas Skacel, Roger von Moos and Reinhard Dummer
17 Epidermal Growth Factor Receptor Inhibitor Reactions, 184Yevgeniy Balagula and Mario E. Lacouture
18 Small Molecule Multikinase Inhibitors, 196Caroline Robert, Vincent Sibaud and Christine Mateus
19 Antimicrotubule Agents, 208Claus Garbe
20 Histone Deacetylase Inhibitors, Proteasome Inhibitors, Demethylating Agents, Arsenicals, and Retinoids, 215Najla Al-Dawsari, Shannon C. Trotter and Francine Foss
21 Miscellaneous Reactions, 224Katharina C. Kaehler, Christine B. Boers-Doets, Mario E. Lacouture and Axel Hauschild
22 Skin Toxicities due to Biotherapy, 233Kathryn T. Ciccolini, Katharina C. Kaehler, Mario E. Lacouture and Axel Hauschild
23 Monoclonal Antibodies, 241Caroline Robert
24 Endocrine Agents, 248Katherine Szyfelbein Masterpol, Maura Dickler and Mario E. Lacouture
25 Agents for the Management of Hematologic Reactions, 257Mee-young Lee and Caroline C. Kim
26 Radiation-Induced Skin Reactions, 264Rebecca K.S. Wong and Zahra Kassam
27 Hematopoietic Stem Cell Transplantation and Graft Versus Host Disease, 281Stephanie W. Hu and Jonathan Cotliar
28 Extravasation Reactions, 295Seppo W. Langer
29 Topical Anticancer Therapies, 301Patricia L. Myskowski
30 Life-threatening (Serious) Dermatologic Adverse Events, 310Milan J. Anadkat
31 Dermatologic Infections, 319Yevgeniy Balagula, Mario E. Lacouture and James I. Ito
Section 5 Late Cutaneous Events from Cancer Treatment
32 Late Dermatologic Conditions, 339Jennifer Nam Choi
Section 6 Dermatologic Practice in Oncology
33 Management Algorithms for Dermatologic Adverse Events, 367Alyx Rosen, Iris Amitay-Laish and Mario E. Lacouture
34 Dermatologic Therapeutics and Formulations, 384Judy H. Borovicka, Jennifer R.S. Gordon, Ann Cameron Haley, Nicole E. Larsen and Dennis P. West
35 Dermatologic Techniques and Procedures, 401Robert Eilers Jr., Kishwer S. Nehal and Erica H. Lee
36 Appearance-Related Concerns in the Cancer Patient, 410Amy J. Derick
Index, 417