Design and Analysis of Clinical Experiments / Edition 1

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Overview

The Wiley Classics Library consists of selected books that have become recognized classics in their respective fields. With these new unabridged and inexpensive editions, Wiley hopes to extend the life of these important works by making them available to future generations of mathematicians and scientists. Currently available in the Series: T.W. Anderson The Statistical Analysis of Time Series T.S. Arthanari & Yadolah Dodge Mathematical Programming in Statistics Emil Artin Geometric Algebra Norman T. J. Bailey The Elements of Stochastic Processes with Applications to the Natural Sciences Robert G. Bartle The Elements of Integration and Lebesgue Measure George E. P. Box & Norman R. Draper Evolutionary Operation: A Statistical Method for Process Improvement George E. P. Box & George C. Tiao Bayesian Inference in Statistical Analysis R. W. Carter Finite Groups of Lie Type: Conjugacy Classes and Complex Characters R. W. Carter Simple Groups of Lie Type William G. Cochran & Gertrude M. Cox Experimental Designs, Second Edition Richard Courant Differential and Integral Calculus, Volume I Richard Courant Differential and Integral Calculus, Volume II Richard Courant & D. Hilbert Methods of Mathematical Physics, Volume I Richard Courant & D. Hilbert Methods of Mathematical Physics, Volume II D. R. Cox Planning of Experiments Harold S. M. Coxeter Introduction to Geometry, Second Edition Charles W. Curtis & Irving Reiner Representation Theory of Finite Groups and Associative Algebras Charles W. Curtis & Irving Reiner Methods of Representation Theory with Applications to Finite Groups and Orders, Volume I Charles W. Curtis & Irving Reiner Methods of Representation Theory with Applications to Finite Groups and Orders, Volume II Bruno de Finetti Theory of Probability, Volume I Bruno de Finetti Theory of Probability, Volume 2 W. Edwards Deming Sample Design in Business Research Amos de Shalit & Herman Feshbach Theoretical Nuclear Physics, Volume 1—Nuclear Structure Harold F. Dodge & Harry G. Romig Sampling Inspection Tables: Single and Double Sampling J. L. Doob Stochastic Processes Nelson Dunford & Jacob T. Schwartz Linear Operators, Part One, General Theory Nelson Dunford & Jacob T. Schwartz Linear Operators, Part Two, Spectral Theory—Self Adjoint Operators in Hilbert Space Nelson Dunford & Jacob T. Schwartz Linear Operators, Part Three, Spectral Operators Regina C. Elandt-Johnson & Norman L. Johnson Survival Models and Data Analysis Herman Feshbach Theoretical Nuclear Physics: Nuclear Reactions Joseph L. Fleiss Design and Analysis of Clinical Experiments Bernard Friedman Lectures on Applications-Oriented Mathematics Phillip Griffiths & Joseph Harris Principles of Algebraic Geometry Gerald J. Hahn & Samuel S. Shapiro Statistical Models in Engineering Marshall Hall, Jr. Combinatorial Theory, Second Edition Morris H. Hansen, William N. Hurwitz & William G. Madow Sample Survey Methods and Theory, Volume I—Methods and Applications Morris H. Hansen, William N. Hurwitz & William G. Madow Sample Survey Methods and Theory, Volume II—Theory Peter Henrici Applied and Computational Complex Analysis, Volume 1—Power Series—Integration—Conformal Mapping—Location of Zeros Peter Henrici Applied and Computational Complex Analysis, Volume 2—Special Functions—Integral Transforms—Asymptotics—Continued Fractions Peter Henrici Applied and Computational Complex Analysis, Volume 3—Discrete Fourier Analysis— Cauchy Integrals—Construction of Conformal Maps—Univalent Functions Peter Hilton & Yel-Chiang Wu A Course in Modern Algebra Harry Hochstadt Integral Equations Leslie Kish Survey Sampling Shoshichi Kobayashi & Katsumi Nomizu Foundations of Differential Geometry, Volume I Shoshichi Kobayashi & Katsumi Nomizu Foundations of Differential Geometry, Volume 2 Erwin O. Kreyszig Introductory Functional Analysis with Applications William H. Louisell Quantum Statistical Properties of Radiation Rupert G. Miller Jr. Survival Analysis Ali Hasan Nayfeh Introduction to Perturbation Techniques Ali Hasan Nayfeh & Dean T. Mook Nonlinear Oscillations Emanuel Parzen Modern Probability Theory & Its Applications P. M. Prenter Splines and Variational Methods Walter Rudin Fourier Analysis on Groups Lawrence S. Schulman Techniques and Applications of Path Integration Shayle R. Searle Linear Models I. H. Segel Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems C. L. Siegel Topics in Complex Function Theory, Volume I—Elliptic Functions and Uniformization Theory C. L. Siegel Topics in Complex Function Theory, Volume II—Automorphic and Abelian Integrals C. L. Siegel Topics in Complex Function Theory, Volume III—Abelian Functions and Modular Functions of Several Variables L. Spitzer Physical Processes in the Interstellar Medium J. J. Stoker Differential Geometry J. J. Stoker Water Waves: The Mathematical Theory with Applications J. J. Stoker Nonlinear Vibrations in Mechanical and Electrical Systems Richard Zallen The Physics of Amorphous Solids Arnold Zellner Introduction to Bayesian Inference in Econometrics

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Editorial Reviews

Booknews
A guide for clinical investigators and biostatisticians in biomedical research centers and the pharmaceutical industry who are responsible for designing clinical experiments and for analyzing resulting data. Real examples from such specialties as cardiology, dentistry, gerontology, neurology, pediatrics, and psychiatry are used to illustrate designs and their analyses. Includes numerical and algebraic chapter problems. Can be used as a text for a second-year, graduate-level course. First published in 1986 by John Wiley & Sons. Annotation c. by Book News, Inc., Portland, Or.
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Product Details

  • ISBN-13: 9780471349914
  • Publisher: Wiley
  • Publication date: 2/22/1999
  • Series: Wiley Classics Library Series , #73
  • Edition description: New Edition
  • Edition number: 1
  • Pages: 448
  • Sales rank: 1,385,086
  • Product dimensions: 6.06 (w) x 9.04 (h) x 0.81 (d)

Table of Contents

1 Reliability of Measurement 1
2 Simple Linear Regression Analysis 33
3 The Parallel Groups Design 46
4 Special Cases of the Parallel Groups Study 91
5 Blocking to Control for Prognostic Variables 120
6 Stratification to Control for Prognostic Variables 149
7 Analysis of Covariance and the Study of Change 186
8 Repeated Measurements Studies 220
9 Latin and Greco-Latin Squares 241
10 The Crossover Study 263
11 Balanced Incomplete Block Designs 291
12 Factorial Experiments 306
13 Split-Plot Designs and Confounding 348
App Sample-Size Determination 369
Author Index 419
Subject Index 423
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